Results 81 to 90 of about 424,865 (327)

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

Advanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini, Andrea Ciamarone, Sheila Dakhel Plaza, Tony Georgiev, Marta Mascellani, Emanuela Sabato, Giulio Vistoli, Ilaria Biancofiore, Nicholas Favalli, Emanuele Puca, Sebastian Oehler, Dario Neri, Samuele Cazzamalli   +12 more
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

Advanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan, Xin‐Ning Li, Zhong‐Liang Peng, Wei Wu, Zeng Wang, Zhao‐Ran Zhu, Jia‐Chang Liu, Yao Wang, Jin‐Long Ren, Zhi‐Yi Zhang, Jia‐Tang Li   +10 more
wiley   +1 more source

Solving the G-problems in less than 500 iterations: Improved efficient constrained optimization by surrogate modeling and adaptive parameter control [PDF]

, 2015
Constrained optimization of high-dimensional numerical problems plays an important role in many scientific and industrial applications. Function evaluations in many industrial applications are severely limited and no analytical information about ...
Bagheri, Samineh, Bäck, Thomas, Emmerich, Michael, Konen, Wolfgang   +3 more
core   +2 more sources

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Maintaining Health Insurance During a Recession: Likely COBRA Eligibility [PDF]

, 2009
Assesses laid-off workers' eligibility and financial ability to extend employer-sponsored insurance through COBRA. Recommends extending COBRA and providing premium assistance, as well as expanding Medicaid and State Children's Health Insurance ...
Cathy Schoen, Michelle M. Doty, Sara R. Collins, Sheila D. Rustgi   +3 more
core  

Scale‐Down Analysis of Fouling in Cell Retention Devices for the Continuous Production of Monoclonal Antibodies

Journal of Advanced Manufacturing and Processing, EarlyView.
ABSTRACT The use of perfusion bioreactor systems is increasing in biomanufacturing due to their potential for productivity gains, increased facility utilization, and process intensification. Systematic studies on cell retention devices are limited even if these devices are often described as process‐limiting during perfusion.
Delphine Tavernier, Timothy Erlandson, Andrea C. M. E. Rayat   +2 more
wiley   +1 more source

Consecutive bites on two persons by the same cobra: a case report

Journal of Venomous Animals and Toxins including Tropical Diseases, 2008
In tropical countries like Bangladesh, persons are bitten by snakes every day and a considerable number of patients die en route to the hospital. An event of consecutive neurotoxic bites on two men by a single snake was observed in the Snake Bite Study ...
MR Amin, SMH Mamun, NH Chowdhury, M Rahman, A Ghose, A Al Hasan, MA Faiz   +6 more
doaj   +1 more source

Enhancing the decision-making process of project managers in the built environment: An integrated approach [PDF]

, 2008
A study of the project manager’s (PM) function must be to examine: what their role is, their skills, and training needed. The project manager needs wide perspective regarding the classic management functions of control, coordination, communication, and ...
Fairhurst, D, John, G A, RICS - COBRA, Wardle, I   +3 more
core  

Culturally Modified Trees and Bark and Wooden Material Culture From Yagara Country, Southeast Queensland, Australia: A Preliminary Overview of Indigenous Biocultural Knowledge

Archaeology in Oceania, EarlyView.
ABSTRACT This paper outlines preliminary results from our multimethod research about Culturally Modified Trees (CMTs) and associated bark and wooden material culture in Yagara Country in southeast Queensland. Methods employed include historical source and modern database analysis, archaeological field surveys, semi‐structured interviews with Yagara ...
Kate Greenwood, Amy Roberts, Madonna Thomson, James Bonner   +3 more
wiley   +1 more source

Delivered cost of switchgrass pellets transported from depots to a biorefinery in the Piedmont, USA

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The southeast region of the USA has the potential to be a significant producer of biobased products; however, research is needed to demonstrate the most cost‐effective feedstock delivery system. This study considers a distributed network of five pellet depots to supply feedstock (i.e., switchgrass pellets) for the operation of a hypothetical ...
Jonathan P. Resop, John S. Cundiff, Shahabaddine Sokhansanj   +2 more
wiley   +1 more source