La interacción constante del organismo humano con diferentes sustancias, que incluso en muchas ocasiones se consideran inofensivas, tiene un alto impacto sobre todos los sistemas, siendo el cardiovascular uno de los más afectados.
Lukas Salazar +2 more
doaj
Alcohol and cocaine (COC) are commonly co-used drugs that cause addiction and have harmful effects. Their abuse may threaten the health of the abuser and public safety by causing serious accidents or crimes.
Dong Won Shin +3 more
doaj +1 more source
Aislamiento de cocaína y benzoilecgonina en muestras de orina por extracciones líquido-líquido y en fase sólida y confirmación por Cromatografía líquida de alta resolución (HPLC) [PDF]
El consumo ilícito de cocaína se ha incrementado extraordinariamente en los últimos años, por lo que resulta indispensable el desarrollo de metodologías seguras, rápidas y eficientes para su detección. En este trabajo se desarrollo una técnica de HPLC de
Arcay Torres, S. +3 more
core
Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P +11 more
core +1 more source
Current status of keratinized matrices in Toxicology: Comparison of hair and nails
Results of hair, fingernail, and toenail concentrations of drugs of abuse and pharmaceuticals in the literature are reviewed and differences between both matrices are evaluated in order to evaluate the usefulness of nail samples as an alternative to hair.
M. Cobo‐Golpe +2 more
wiley +1 more source
Improving the prediction of in-sewer transformation of illicit drug biomarkers by identifying a new modelling framework [PDF]
In the context of wastewater-based epidemiology, uncertainties associated with in-sewer transformation are often not considered. However, sewer systems are biological reactors in which the concentration of organic pollutants (primary pollutants, e.g. COD,
Brock, Andreas Libonati +4 more
core
Cocaine influences alcohol-seeking behavior and relapse drinking in alcohol-preferring (P) rats [PDF]
BACKGROUND: The results of several studies suggest that there may be common neurocircuits regulating drug-seeking behaviors. Common biological pathways regulating drug-seeking would explain the phenomenon that seeking for 1 drug can be enhanced by ...
Deehan Jr., Gerald A. +4 more
core +1 more source
Substance use in Guyana: Echoes of the colonial past
Abstract The impact of intoxicating substances both licit and illicit has been integral to expressions of colonial power and the control of colonised populations, including in Caribbean societies. Historically, licensing laws and carceral institutions were used to discipline workers, and the ongoing criminalisation of certain drugs illustrates the ...
Tammy C. Ayres +2 more
wiley +1 more source
Comprehensive Review of Cocaethylene and Cocaine Concentrations in Patients [PDF]
Cocaethylene (CE) and cocaine (COC) concentrations were reviewed for 41 patients studied by this laboratory and found to have measurable CE in plasma. In 17 instances, urine concentrations of CE and COC were also measured. In 15 cases other drugs in addition to COC and ethanol (ETOH) were detected. Thirty-three cases involved trauma.
openaire +2 more sources
Ambient ionisation mass spectrometry for drug and toxin analysis: A review of the recent literature
Ambient ionization mass spectrometry enables the rapid, real‐time analysis of samples in their native state. This review highlights recent developments in the use of ambient ionization for drugs analysis across various fields, including forensics, anti‐doping, food safety, pharmaceuticals, environmental sciences, and diagnostic testing.
Alisha Henderson +2 more
wiley +1 more source

