Results 51 to 60 of about 67,569 (184)
Analytical Science Advances, Volume 6, Issue 1, June 2025.ABSTRACT Liquid chromatography–mass spectrometry (LC–MS) is a highly sophisticated analytical technique that has become indispensable for sample analysis across various scientific domains. In recent years, LC–MS has emerged as a cornerstone technology in comparative replicate sample analysis, particularly in the fields of proteomics, lipidomics and ...
Samyah Alanazi
wiley +1 more source
Drug Testing and Analysis, Volume 17, Issue 6, Page 751-760, June 2025.This report describes the potential of vacuum differential mobility spectrometry (DMS) as an additional separation dimension to reduce liquid chromatography (LC‐MS) analysis time while maintaining good quantitative performance. A 1‐min trap/elute LC‐vDMS‐SIM/MS method for quantification of 11 drugs of abuse was developed and applied to the analysis of ...
Maria Fernanda Cifuentes Girard +2 more
wiley +1 more source
Cocaethylene: A neuropharmacologically active metabolite assciated with concurrent cocaine-ethanol ingestion [PDF]
, 1991 High concentrations of cocaethylene (EC), the ethyl ester of benzoylecgonine, were measured in the blood of individuals who had concurrently used cocaine and ethanol.
Winger, Gail D. +6 more
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Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS
Drug Testing and Analysis, Volume 17, Issue 6, Page 903-914, June 2025.A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces +5 more
wiley +1 more source
, 2017 The molecular conformation and supramolecular architecture of cocaethylene [systematic name: ethyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate], C18H23NO4, have been determined for the first time.
Ângelo De Fátima +5 more
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Current status of keratinized matrices in Toxicology: Comparison of hair and nails
Drug Testing and Analysis, Volume 17, Issue 3, Page 436-449, March 2025.Results of hair, fingernail, and toenail concentrations of drugs of abuse and pharmaceuticals in the literature are reviewed and differences between both matrices are evaluated in order to evaluate the usefulness of nail samples as an alternative to hair.
M. Cobo‐Golpe +2 more
wiley +1 more source
Comprehensive Review of Cocaethylene and Cocaine Concentrations in Patients [PDF]
American Journal of Clinical Pathology, 1996 Cocaethylene (CE) and cocaine (COC) concentrations were reviewed for 41 patients studied by this laboratory and found to have measurable CE in plasma. In 17 instances, urine concentrations of CE and COC were also measured. In 15 cases other drugs in addition to COC and ethanol (ETOH) were detected. Thirty-three cases involved trauma.
openaire +2 more sources
Substance use in Guyana: Echoes of the colonial past
The Howard Journal of Crime and Justice, Volume 63, Issue 4, Page 390-417, December 2024.Abstract The impact of intoxicating substances both licit and illicit has been integral to expressions of colonial power and the control of colonised populations, including in Caribbean societies. Historically, licensing laws and carceral institutions were used to discipline workers, and the ongoing criminalisation of certain drugs illustrates the ...
Tammy C. Ayres +2 more
wiley +1 more source
, 2004 When cocaine and ethanol are taken together a cocaine metabolite called cocaethylene is produced. Investigators have determined that cocaine, ethanol, and cocaethylene all produce a conditioned place preference when administered intraperitoneally. On the
White, Sasha L. +2 more
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Ambient ionisation mass spectrometry for drug and toxin analysis: A review of the recent literature
Drug Testing and Analysis, Volume 16, Issue 11, Page 1323-1344, November 2024.Ambient ionization mass spectrometry enables the rapid, real‐time analysis of samples in their native state. This review highlights recent developments in the use of ambient ionization for drugs analysis across various fields, including forensics, anti‐doping, food safety, pharmaceuticals, environmental sciences, and diagnostic testing.
Alisha Henderson +2 more
wiley +1 more source