Results 31 to 40 of about 67,744 (195)
Cocaine- and Cocaethylene-Creatinine Clearance Ratios in Humans [PDF]
Journal of Analytical Toxicology, 1997 Cocaine (COC)- and cocaethylene (CE)-creatinine clearance ratios (CCR) were determined in five patients. In each case, COC:CCR greatly exceeded CE:CCR, and in four patients the data suggested renal tubular secretion of COC. For all patients, some renal tubular reabsorption of CE was apparent.
D N, Bailey, J B, Bessler, B A, Sawrey
openaire +2 more sources
An exploratory study of information sources and key findings on UK cocaine-related deaths. [PDF]
, 2017 Cocaine-related deaths have increased since the early 1990s in Europe, including the UK. Being multi-factorial, they are difficult to define, detect and record.
Arendt M +11 more
core +3 more sources
, 2010 The use of cocaine may be associated with either acute or chronic toxicity, and approximately 5% to 10% of emergency department visits in the United States are believed to be secondary to cocaine usage.
Figueredo, M.D., Vincent M +2 more
core +2 more sources
Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]
, 1997 Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M. +2 more
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Drug Testing and Analysis, EarlyView.Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão +4 more
wiley +1 more source
Journal of Forensic Sciences, EarlyView.Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort +8 more
wiley +1 more source
Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]
, 1997 Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M. +3 more
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Addiction, EarlyView.Abstract Aim To monitor community‐level consumption of 20 illicit drugs across urban areas of England using wastewater‐based epidemiology (WBE) surveillance at high temporal resolution. Design, setting, cases This study was conducted over a 12‐month period in 2022 sampling 24‐hour composite wastewater samples at 15 wastewater treatment plants (WWTPs ...
Helena Rapp‐Wright +14 more
wiley +1 more source
Fragmentation pathways of drugs of abuse and their metabolites based on QTOF MS/MS and MSE accurate-mass spectra [PDF]
, 2011 A study of the fragmentation pathways of several classes of drugs of abuse (cannabinoids, ketamine, amphetamine and amphetamine-type stimulants (ATS), cocaine and opiates) and their related substances has been made.
Bijlsma, Lubertus +3 more
core +2 more sources
Transcendencia del cocaetileno en el consumo combinado de etanol y cocaína [PDF]
, 2006 Cada vez es más frecuente encontrar a nivel asistencial las repercusiones del consumo abusivo de cocaína y etanol.La interacción metabólica del etanol y la cocaína da lugar a un nuevo metabolito denominado cocaetileno, el cual juega un papel importante ...
Caja Calvo, Marta +5 more
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