Results 11 to 20 of about 67,569 (184)
Forensic Drug Profile: Cocaethylene [PDF]
Journal of Analytical Toxicology, 2019 This article is intended as a brief review or primer about cocaethylene (CE), a pharmacologically active substance formed in the body when a person co-ingests ethanol and cocaine.
Jones, A Wayne,
core +3 more sources
Cocaethylene and suicidality: an exploratory systematic review [PDF]
Journal of Substance UseBackgroundThere is evidence that both cocaine and alcohol lead to an increased risk of suicide. However, cocaethylene (a metabolite created from their co-ingestion) and suicidality are underexamined, and there has yet to be a systematic review of the ...
Lewis, Amy +4 more
core +2 more sources
Factors Associated With Cocaine Use Disorder: Results From the French Nationwide Repeated Cross-Sectional OPPIDUM Study (2019-2023). [PDF]
Fundam Clin PharmacolABSTRACT Cocaine use has increased both globally and nationally. This trend is accompanied by a rise in clinical complications. The objective of our study was to identify factors observed to be associated with cocaine use disorder, using data from the OPPIDUM program, collecting information directly from patients with substance use disorders recruiting
Alhamidi Z +5 more
europepmc +2 more sources
Combined Ethanol, Cocaine, Heroin and Methadone Abuse: a Deadly Mix, Review of the Literature [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Background: Polysubstance use or abuse is defined as the ingestion or use of more than one drug of abuse within a defined time frame, aiming to enhance or modulate psychoactive effects, alleviate unwanted side effects of one substance and free access to ...
Maryam Akhgari +2 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2022 We analyzed the thermodynamics of binding of cocaine and several cocaine metabolites to a humanized anti-cocaine mAb (h2E2), which is under development for the treatment of cocaine use disorders, using isothermal titration calorimetry.
Terence L. Kirley, Andrew B. Norman
doaj +1 more source
Química Nova, 2021 This study aimed to investigate a miniaturized extraction methodology with analysis by GC-MS for simultaneous detection and quantification of cocaine (COC), benzoylecgonine (BZE) and cocaethylene (CE) in hair to monitor drug addicts. The process was done
Deborah Thais Palma Scanferla +11 more
doaj +1 more source
Green Analytical Chemistry, 2023 The purpose of the research was to develop a new method that would allow the determination of selected drugs (mephedrone, MDMA, and cocaine and its metabolites: benzoylecgonine, norcocaine, and cocaethylene) in whole blood, while meeting not only the ...
Alicja Chromiec +2 more
doaj +1 more source
Toxins, 2022 Cocaine is one of the most consumed stimulants throughout the world, as official sources report. It is a naturally occurring sympathomimetic tropane alkaloid derived from the leaves of Erythroxylon coca, which has been used by South American locals for ...
Rita Roque Bravo +7 more
doaj +1 more source