Results 211 to 220 of about 265,487 (267)

Baclofen Modulates Neural Intrinsic Functional Connectivity in Treatment‐Seeking Individuals With Alcohol Use Disorder

Alcohol, Clinical and Experimental Research, Volume 50, Issue 6, June 2026.
In a randomized, double‐blind study of individuals with alcohol use disorder, high‐dose baclofen (75 mg/day) compared with placebo was associated with differences in resting‐state functional connectivity, with higher connectivity in reward and stress‐related regions and lower connectivity in attentional and salience networks.
Warren B. Logge, Tristan P. Hurzeler, Paul S. Haber, Laurence Mealing, Andrew J. Baillie, Kirsten C. Morley   +5 more
wiley   +1 more source

Glucagon-like peptide 1 receptor agonists in substance use disorders: A systematic review of ClinicalTrials.Gov. [PDF]

Addict Behav Rep
Patil S, Jha N, Jha MK.
europepmc   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, Volume 121, Issue 6, Page 1580-1593, June 2026.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

An evaluation of N-acetylcysteine in a sequential oxycodone and cocaine rat self-administration model. [PDF]

Exp Clin Psychopharmacol
Corley C, McNealy KR, White AM, McManus H, Khatri SN, Stoops WW, Gipson CD.   +6 more
europepmc   +1 more source

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Placental Pathophysiology in Maternal Psychoactive Substance Use: Biological, Clinical, and Forensic Perspectives. [PDF]

Cells
Fraile-Martinez O, Rubio-Bedoya N, García-Montero C, Boaru DL, de Castro-Martinez P, Bujan J, López-González L, Díaz-Pedrero R, García-Honduvilla N, Álvarez-Mon M, Saez MA, De León-Luis JA, Bravo C, Ortega MA.   +13 more
europepmc   +1 more source

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias

Addiction, Volume 121, Issue 6, Page 1616-1621, June 2026.
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley   +1 more source

Cocaine disrupts hidden states in the brain. [PDF]

Elife
Le M, Keiflin R.
europepmc   +1 more source

The Polysubstance Assessment Tool: Reliability, acceptability and feasibility of a novel measure of polysubstance use

Addiction, Volume 121, Issue 6, Page 1410-1420, June 2026.
Abstract Background and aims There are currently no brief quantitative assessments that capture the drug patterns of people who engage in use of more than one drug on the same day or simultaneously. The current study examined the retest reliability, acceptability and feasibility of a new quantitative assessment to measure polysubstance use.
Amanda M. Bunting, Charles M. Cleland, S. Michaela Barratt, Brittany Griffin, Jaimee Williams, Carrie B. Oser, Joshua D. Lee, Jennifer McNeely   +7 more
wiley   +1 more source

Exploring the intersection of heavy alcohol use and masculine norms as risk factors for male‐to‐female intimate partner violence: Evidence from an Australian national survey

Addiction, Volume 121, Issue 6, Page 1445-1457, June 2026.
Abstract Background and aims Endorsement of traditional masculine norms and male alcohol use are identified risk factors for male‐to‐female intimate partner violence (MFIPV) perpetration, yet their interaction remains unexplored in Australia. This study aimed to estimate the associations between heavy male alcohol use, endorsement of traditional ...
Bree Willoughby, Koen Smit, Ingrid M. Wilson, Gail Gilchrist, Anne‐Marie Laslett   +4 more
wiley   +1 more source