Results 91 to 100 of about 40,355 (156)
Synthesis and Pharmacology of Ester Modified (+/-)-threo-Methylphenidate Analogs [PDF]
As part of a program to develop compounds with potential to treat cocaine abuse, eleven (+/-)-threo-methylphenidate (TMP; Ritalin) derivatives were synthesized and tested in rat striatal tissue preparations for inhibitory potency against [3H]WIN 35,428 binding (WIN) to the dopamine (DA) transporter, [3H]citalopram binding (CIT) to the serotonin ...
arxiv
Site of inhibitory action of cocaine on cellular respiration [PDF]
Brenda E. Ryman, E.O'F. Walsh
openalex +1 more source
EASI Drugs in the Streets of Colombia: Modeling Heterogeneous and Endogenous Drug Preferences [PDF]
The response of illicit drug consumers to large-scale policy changes, such as legalization, is heavily mediated by their demand behavior. Since individual drug use is driven by many unobservable factors, accounting for unobserved heterogeneity is crucial for modeling demand and designing targeted public policies. This paper introduces a finite Gaussian
arxiv
CXXIII.—The relation between the absorption spectra and constitution of piperine, nicotine, cocaine, atropine, hyoscyamine, and hyoscine [PDF]
James J. Dobbie, John Jacob Fox
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The hypocretins/orexins (HCRT) have been demonstrated to influence motivation for cocaine through actions on dopamine (DA) transmission. Pharmacological or genetic disruption of the hypocretin receptor 1 (Hcrtr1) reduces cocaine self-administration ...
Emily M. Black+6 more
doaj
Muon Imaging for Illicit Cargo Detection: A Simulation-Based Study [PDF]
This study evaluates the potential of muon tomography as a non-invasive technique for detecting concealed illicit drugs in cargo, based on detailed simulations performed using the GEANT4 toolkit. A combined analysis of muon scattering and absorption data was employed to enhance material discrimination, with a focus on realistic smuggling scenarios ...
arxiv
ON THE EFFECT OF COCAINE UPON SODIUM-DEFICIENT FROG NERVE [PDF]
R. Lorente de Nó
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ON THE USE OF COCAINE FOR PRODUCING ANÆSTHESIA ON THE EYE. [PDF]
Carl Koller
openalex +1 more source
Mirtazapine decreased cocaine-induced c-fos expression and dopamine release in rats
IntroductionChronic cocaine exposure induces an increase in dopamine release and an increase in the expression of the Fos protein in the rat striatum.
Susana Barbosa-Méndez+1 more
doaj +1 more source