Results 81 to 90 of about 160,082 (298)

A latent class analysis of the past-30-day substance use patterns among lifetime cocaine users: Findings from a community sample in North Central Florida

Addictive Behaviors Reports, 2019
Objectives: Cocaine use is increasing and many cocaine users engage in polysubstance use. Within polysubstance use, relationships among use of individual substances are necessarily complex.
Yiyang Liu, Amy L. Elliott, Mirsada Serdarevic, Robert F. Leeman, Linda B. Cottler   +4 more
doaj   +1 more source

Cocaine-induced conditioned taste aversions: Investigations of neurochemical mediation

, 2012
Drugs of abuse have both rewarding and aversive effects, and it is the balance of these effects which impact abuse vulnerability. Although research has traditionally focused on the rewarding effects of drugs, their aversive effects have recently gained ...
Katherine M. Serafine (16757310)
core   +1 more source

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević, Luka Horvat, Vito Papić, Andrija Štajduhar   +3 more
wiley   +1 more source

Transdiagnostic and symptom‐domain associations between mental illnesses and future self‐connectedness versus future self‐valence

JCPP Advances, EarlyView.
Abstract Background Future time perspective dimensions have been linked to various mental illnesses. Given the tendency for mental illnesses to co‐occur, it is necessary to disentangle associations between future‐oriented constructs and shared versus symptom‐domain‐specific psychopathology.
Yi Yang, Ingrid Obsuth, Jean‐Louis van Gelder, Denis Ribeaud, Manuel Eisner, Xinxin Zhu, Aja Louise Murray   +6 more
wiley   +1 more source

Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats

Scientific Reports
Cocaine dependence is a serious world-wide public health problem without an FDA-approved pharmacotherapy. We recently designed and discovered a highly efficient long-acting cocaine hydrolase CocH5-Fc(M6).
Huimei Wei, Johnathan E. LeSaint, Zhenyu Jin, Chang-Guo Zhan, Fang Zheng   +4 more
doaj   +1 more source

Corticostriatal cocaine-seeking ensembles are defined by differing gene expression from sucrose-seeking ensembles using a within-subject dual self-administration and seeking mouse model

Addiction Neuroscience
Recurrent cocaine seeking is a hallmark of cocaine use disorder. To develop therapeutic targets, it is critical to understand the neurobiological changes specific to cocaine-seeking in context with the seeking of non-drug rewards, e.g., sucrose.
Carl G. Litif, Levi T. Flom, Kathryn L. Sandum, Skylar L. Hodgins, Lucio Vaccaro, Jerry A. Stitzel, Nathan Ungerleider, Maria Constanza Mannino, Jason P. Gigley, Todd A. Schoborg, Ana-Clara Bobadilla   +10 more
doaj   +1 more source

Cocaine abuse : behavior, pharmacology, and clinical applications /

, 1998
Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of
Higgins, Stephen T., Katz, Jonathan L.
core  

Healing together: Results from a pilot trial of 3,4‐Methylenedioxymethamphetamine‐enhanced cognitive‐behavioral conjoint therapy for posttraumatic stress disorder

Journal of Traumatic Stress, EarlyView.
Abstract Posttraumatic stress disorder (PTSD) disrupts individual well‐being and relationship health, particularly among veteran/military couples with heightened risks due to deployment, family reintegration, and traumatic stress. Although cognitive‐behavioral conjoint therapy (CBCT) and brief CBCT (bCBCT) have demonstrated strong efficacy in reducing ...
Leslie A. Morland, Chandra E. Khalifian, Dimitri Perivoliotis, Bettye Chargin, Al Alam, Tamara R. Wachsman, Dhakshin Ramanathan, Andrew W. Bismark, Christopher Stauffer, Anne C. Wagner, Abigail C. Angkaw, Kayla C. Knopp   +11 more
wiley   +1 more source

Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres, Jessi M. Larrinaga, Katherine Bodiford, Olayemi Sokumbi, Leila Tolaymat   +4 more
wiley   +1 more source

Functional Neurogenomics of Cocaine

, 2002
Dissertation prepared under the direction of Kent E. Vrana, Ph.D., Associate Professor of Physiology and Pharmacology and Director of Graduate Studies Chronic cocaine abuse causes altered neuronal gene expression, morphology, and physiology.
Freeman, Willard Morgan
core