Results 61 to 70 of about 309,381 (308)

Stress-Induced Cocaine Seeking Requires a Beta-2 Adrenergic Receptor-Regulated Pathway from the Ventral Bed Nucleus of the Stria Terminalis That Regulates CRF Actions in the Ventral Tegmental Area [PDF]

, 2014
The ventral bed nucleus of the stria terminalis (vBNST) has been implicated in stress-induced cocaine use. Here we demonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that innervate the ventral tegmental area (VTA)
Baker, David A., Gasser, Paul J, Gerndt, Clayton H., Mantsch, John R., Vranjkovic, Oliver   +4 more
core   +2 more sources

Cocaine-induced Vasculitis [PDF]

Rambam Maimonides Medical Journal, 2016
The use of cocaine continues to grow worldwide. One of the possible side-effects of cocaine is vasculitis. Two distinct vasculitic syndromes have been described due to cocaine. One is cocaine-induced midline destructive lesion, secondary to a direct vasoconstrictor effect of cocaine, inducing ischemic necrosis of the septal cartilage and perforation of
Mark Berman, Daphna Paran, Ori Elkayam
openaire   +3 more sources

Influence of Different Washing Hair Procedures in the Quantitative Determination of THC and THCCOOH

Drug Testing and Analysis, EarlyView.
Different hair decontamination protocols significantly affect THC quantification, with marked analyte loss—particularly after aqueous‐organic washing—whereas THCCOOH remains stable. These findings highlight the risk of misinterpretation and the need for standardized washing procedures in hair analysis.
Valentina Martini, Alessandro Raffagli, Cristiana Stramesi, Claudia Vignali, Stefania Ortu, Paolo Franceschini, Ilaria Baudone, Paolo Bucchioni, Luca Morini   +8 more
wiley   +1 more source

Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse

Epigenetics, 2022
Despite more than 2 million American cocaine users monthly, there is no approved drug for treating cocaine use disorder. Cocaine use disorder has a multifactorial aetiology, including both genetic and environmental factors.
Aysheh Alrfooh, Ryan M. Smith
doaj   +1 more source

A preliminary longitudinal study of white matter alteration in cocaine use disorder subjects [PDF]

, 2017
Background Previous diffusion tensor imaging (DTI) studies have consistently shown that subjects with cocaine use disorder (CocUD) had altered white matter microstructure in the corpus callosum.
Boone, Edward L., Ma, Liangsuo, Moeller, F. Gerard, Narayana, Ponnada A., Schmitz, Joy M., Steinberg, Joel L., Wang, Qin   +6 more
core   +2 more sources

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source

Melatonin decreases cocaine-induced locomotor activity in pinealectomized rats

Brazilian Journal of Psychiatry
Objective: Several studies have shown that the time of day regulates the reinforcing effects of cocaine. Additionally, melatonin and its MT1 and MT2 receptors have been found to participate in modulation of the reinforcing effects of such addictive drugs
Susana Barbosa-Méndez, Alberto Salazar-Juárez   +1 more
doaj   +1 more source

Cocaine hallucinations

American Journal of Psychiatry, 1978
The author reviews the literature on hallucinations that occur as a result of acute and chronic administration of cocaine. He examined the phenomenology of cocaine hallucinations in a group of 85 recreational cocaine users, 15 of whom reported hallucinatory experiences in visual, tactile, olfactory, auditory, and gustatory modalities.
openaire   +2 more sources

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Cocaine modulates locomotion behavior in C. elegans.

PLoS ONE, 2009
Cocaine, a potent addictive substance, is an inhibitor of monoamine transporters, including DAT (dopamine transporter), SERT (serotonin transporter) and NET (norepinephrine transporter).
Alex Ward, Vyvyca J Walker, Zhaoyang Feng, X Z Shawn Xu   +3 more
doaj   +1 more source