Results 41 to 50 of about 163,677 (304)
The Cerebellum on Cocaine [PDF]
Frontiers in Systems Neuroscience, 2020 The traditional cerebellum's role has been linked to the high computational demands for sensorimotor control. However, several findings have pointed to its involvement in executive and emotional functions in the last decades. First in 2009 and then, in 2016, we raised why we should consider the cerebellum when thinking about drug addiction.
MIQUEL, MARTA +2 more
openaire +4 more sources
British Journal of Clinical Pharmacology, EarlyView.Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen +7 more
wiley +1 more source
Exploring new avenues: Psychedelic‐assisted therapy for young people
British Journal of Clinical Pharmacology, EarlyView.Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou +3 more
wiley +1 more source
A mechanism for the inhibition of neural progenitor cell proliferation by cocaine.
PLoS Medicine, 2008 BackgroundPrenatal exposure of the developing brain to cocaine causes morphological and behavioral abnormalities. Recent studies indicate that cocaine-induced proliferation inhibition and/or apoptosis in neural progenitor cells may play a pivotal role in
Chun-Ting Lee +13 more
doaj +1 more source
Postgraduate Medical Journal, 2005 Abstract Cocaine is the second commonest illicit drug used and the most frequent cause of drug related deaths. Its use is associated with both acute and chronic complications that may involve any system, the most common being the cardiovascular system.
M, Egred, G K, Davis
openaire +2 more sources
Basic Pharmacological Mechanisms of Cocaine
, 1998 The chapter discusses the increasing dopaminergic activity of cocaine, by binding to the dopamine transporter and inhibiting dopamine uptake. The primary method by which dopamine is deactivated after its release into the synapse is also presented.
Sari Izenwasser, Izenwasser, Sari
core +1 more source
An ETH‐LAD trip with unfavourable consequences: A case report
British Journal of Clinical Pharmacology, EarlyView.Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler +6 more
wiley +1 more source
Breaking point: Identifying the factors that predict suspension from school
British Educational Research Journal, EarlyView.Abstract School suspensions are associated with adverse educational and psychosocial outcomes, yet little is known about how structural disadvantage, relational factors, health behaviours, well‐being indicators and school‐level factors jointly predict suspension risk in England.
Stephanie Cahill +5 more
wiley +1 more source
Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse
Epigenetics, 2022 Despite more than 2 million American cocaine users monthly, there is no approved drug for treating cocaine use disorder. Cocaine use disorder has a multifactorial aetiology, including both genetic and environmental factors.
Aysheh Alrfooh, Ryan M. Smith
doaj +1 more source
Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study [PDF]
, 2008 Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin^1^. This increase of synaptic dopamine may cause neurotoxicity^2,3^.
Theodore Lidsky +5 more
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