Results 31 to 40 of about 160,082 (298)
Initial d2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats. [PDF]
PLoS ONE, 2013 The activation of dopamine receptors within the mesolimbic dopamine system is known to be involved in the initiation and maintenance of cocaine use. Expression of the D2 dopamine receptor subtype has been implicated as both a predisposing factor and ...
Kathryn E Merritt, Ryan K Bachtell
doaj +1 more source
Silent Cocaine Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2014 Background: Cocaine poisoning is known for causing severe clinical effects such as tachycardia, hypertension, agitation and confusion. Absence of clinical manifestations in cocaine poisoning is unusual.
Rachid El-Jaoudi +5 more
doaj
Carryover effects to addiction-associated stimuli in a group of marijuana and cocaine users [PDF]
, 2010 Addiction has been characterized as an attentional bias towards drug-related cues. In two experiments we investigate the effects of non-words that have been associatively trained to addiction-related images in a group of marijuana and cocaine users ...
Money, Sharon, Sharma, Dinkar
core +1 more source
Addictive Behaviors ReportsBackground: Craving is a core symptom of cocaine use disorders (CUD). Inducing craving in exposure to substance cues is of relevant interest for numerous clinical applications.
Thomas Lehoux +6 more
doaj +1 more source
Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum
Cell Reports, 2020 Summary: Projections from the nucleus accumbens to the ventral pallidum (VP) regulate relapse in animal models of addiction. The VP contains GABAergic (VPGABA) and glutamatergic (VPGlu) neurons, and a subpopulation of GABAergic neurons co-express ...
Jasper A. Heinsbroek +6 more
doaj +1 more source
Associations amongst form of cocaine used (powder vs crack vs both) and HIV-related outcomes
Addictive Behaviors Reports, 2021 Introduction: Cocaine (including powder and crack) use is common among people with HIV (PWH). We identified socio-demographic and behavioral factors associated with cocaine use (overall and various forms) among PWH; we also examined differences in HIV ...
Yiyang Liu +4 more
doaj +1 more source
Butyrylcholinesterase genetic variants: association with cocaine dependence and related phenotypes.
PLoS ONE, 2013 ObjectiveThe search for genetic vulnerability factors in cocaine dependence has focused on the role that neuroplasticity plays in addiction. However, like many other drugs, the ability of an individual to metabolize cocaine can also influence ...
André Brooking Negrão +6 more
doaj +1 more source
Addiction Neuroscience, 2023 The hypocretins/orexins (HCRT) have been demonstrated to influence motivation for cocaine through actions on dopamine (DA) transmission. Pharmacological or genetic disruption of the hypocretin receptor 1 (Hcrtr1) reduces cocaine self-administration ...
Emily M. Black +6 more
doaj +1 more source
The Cerebellum on Cocaine [PDF]
Frontiers in Systems Neuroscience, 2020 The traditional cerebellum's role has been linked to the high computational demands for sensorimotor control. However, several findings have pointed to its involvement in executive and emotional functions in the last decades. First in 2009 and then, in 2016, we raised why we should consider the cerebellum when thinking about drug addiction.
MIQUEL, MARTA +2 more
openaire +4 more sources