Results 11 to 20 of about 160,082 (298)
The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation. [PDF]
Post-mortem blood drug concentrations vary greatly and as a consequence of post-mortem change and redistribution may not reflect the concentration at the time of death.
Rees, Kelly-Ann
core +9 more sources
Smoked cocaine in socially-depressed areas [PDF]
, 2010 Background: The main objectives of this study are to describe the smoked cocaine user's profile in socially-depressed areas and their needs from a harm-reduction perspective, to investigate their use of smoking crack and compare the acute effects between
Pons-Prat, Montserrat +17 more
core +1 more source
Cocaine vaccine dAd5GNE protects against moderate daily and high-dose "binge" cocaine use.
PLoS ONE, 2020 The cocaine vaccine dAd5GNE is comprised of a disrupted serotype 5 adenovirus gene therapy vector covalently conjugated to the cocaine analog GNE. The vaccine evokes a high titer of circulating anti-cocaine antibodies that prevent cocaine from reaching ...
David F Havlicek +6 more
doaj +1 more source
Conditioned Contribution of Peripheral Cocaine Actions to Cocaine Reward and Cocaine-Seeking [PDF]
Neuropsychopharmacology, 2013 Cocaine has actions in the peripheral nervous system that reliably precede--and thus predict--its soon-to-follow central rewarding effects. In cocaine-experienced animals, the peripheral cocaine signal is relayed to the central nervous system, triggering excitatory input to the ventral tegmental origin of the mesocorticolimbic dopamine system, the ...
Bin, Wang +5 more
openaire +2 more sources
Toxicology Reports, 2019 Crack cocaine smokers inhale, alongside with cocaine, its pyrolysis product, anhydroecgonine methyl ester (AEME). We have previously described AEME neurotoxic effect and its additive effect when co-incubated with cocaine.
Raphael Caio Tamborelli Garcia +6 more
doaj +1 more source
Clinical Cardiology, 2010 AbstractThe use of cocaine may be associated with either acute or chronic toxicity, and approximately 5% to 10% of emergency department visits in the United States are believed to be secondary to cocaine usage. Chest pain is the most common cocaine‐related medical problem, leading to the evaluation of approximately 64 000 patients annually for possible
Maraj, Suraj +2 more
openaire +2 more sources
Addiction Neuroscience, 2023 Drug associated cues are a common relapse trigger for individuals recovering from cocaine use disorder. Sex and ovarian hormones influence patterns of cocaine use and relapse vulnerability, with studies indicating that females show increased cue-induced ...
Claire M. Corbett +2 more
doaj +1 more source
Prenatal cocaine exposure uncouples mGluR1 from Homer1 and Gq Proteins. [PDF]
PLoS ONE, 2014 Cocaine exposure during gestation causes protracted neurobehavioral changes consistent with a compromised glutamatergic system. Although cocaine profoundly disrupts glutamatergic neurotransmission and in utero cocaine exposure negatively affects ...
Kalindi Bakshi +5 more
doaj +1 more source