Results 71 to 80 of about 112,229 (260)

Enforcing environmental law in the Amazon

People and Nature, EarlyView.
Abstract This article identifies the underlying obstacles to enforcement of laws against environmental crimes such as illegal logging, mining and ranching. With four departments (provinces) from Colombia as case studies, it assesses enforcement of the country's main environmental law, Law 2111, which is one of Latin America's strongest. The article has
Mark Ungar, Juan Corredor‐Garcia
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats

Scientific Reports
Cocaine dependence is a serious world-wide public health problem without an FDA-approved pharmacotherapy. We recently designed and discovered a highly efficient long-acting cocaine hydrolase CocH5-Fc(M6).
Huimei Wei, Johnathan E. LeSaint, Zhenyu Jin, Chang-Guo Zhan, Fang Zheng   +4 more
doaj   +1 more source

An interdisciplinary review of the interplay of conflict, socio‐economic factors, and land cover and vegetation dynamics in Colombia

PLANTS, PEOPLE, PLANET, EarlyView.
Colombia's forests play a crucial role in preserving biodiversity and mitigating climate change, but they are currently facing severe degradation, particularly after the 2016 Peace Agreement. Our literature review highlights a growing research interest in this topic and demonstrates how interdisciplinary approaches combining diverse methods can enhance
Estefanía Muñoz, Jesús A. Anaya, Nicola Clerici, Lina M. Estupinan‐Suarez, Isabel Lopera, Solveig Richter, Alejandro Salazar, Carlos A. Sierra, Andrés Tangarife‐Escobar, Miguel D. Mahecha, David Montero, Pablo Palacios‐Rodríguez, Pablo Ramos, Santiago Botía   +13 more
wiley   +1 more source

Corticostriatal cocaine-seeking ensembles are defined by differing gene expression from sucrose-seeking ensembles using a within-subject dual self-administration and seeking mouse model

Addiction Neuroscience
Recurrent cocaine seeking is a hallmark of cocaine use disorder. To develop therapeutic targets, it is critical to understand the neurobiological changes specific to cocaine-seeking in context with the seeking of non-drug rewards, e.g., sucrose.
Carl G. Litif, Levi T. Flom, Kathryn L. Sandum, Skylar L. Hodgins, Lucio Vaccaro, Jerry A. Stitzel, Nathan Ungerleider, Maria Constanza Mannino, Jason P. Gigley, Todd A. Schoborg, Ana-Clara Bobadilla   +10 more
doaj   +1 more source

THE DANGERS OF COCAINE. [PDF]

The Lancet, 1885
n ...
openaire   +2 more sources

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Reduced frontal brain volume in non-treatment seeking cocaine dependent individuals: exploring the role of impulsivity, depression and smoking

Frontiers in Human Neuroscience, 2014
In cocaine-dependent patients, grey matter (GM) volume reductions have been observed in the frontal lobes that are associated with duration of cocaine use.
Cleo Lina Crunelle, Cleo Lina Crunelle, Anne Marije eKaag, Guido eVan Wingen, Hanna E. van den Munkhof, Judith eHomberg, Liesbeth eReneman, Wim eVan Den Brink, Wim eVan Den Brink   +8 more
doaj   +1 more source

COCAINE FUNGUS. [PDF]

The Lancet, 1885
n ...
openaire   +1 more source

Catholic Values and Gender Politics in the Colombian Mass Media: Acción Cultural Popular (ACPO) in the 1970s

Gender &History, EarlyView.
ABSTRACT The 1970s were a decade of huge change for women in Colombia, from the legalisation of divorce to increased access to education, labour market participation and contraception. This article examines how the Catholic non‐governmental organisation Acción Cultural Popular (Popular Cultural Action, ACPO) responded to women's changing roles and ...
Anna Cant
wiley   +1 more source