Results 71 to 80 of about 163,677 (304)
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background Approximately one in four first‐time mothers reach the second stage of labor but cannot have a spontaneous vaginal birth, necessitating an intervention such as forceps to facilitate birth. Objective This study synthesizes evidence comparing severe maternal morbidity (SMM) and neonatal morbidity or mortality (SNMM) following forceps ...
Irina I. Oltean +2 more
wiley +1 more source
Cocaine modulates locomotion behavior in C. elegans.
PLoS ONE, 2009 Cocaine, a potent addictive substance, is an inhibitor of monoamine transporters, including DAT (dopamine transporter), SERT (serotonin transporter) and NET (norepinephrine transporter).
Alex Ward +3 more
doaj +1 more source
4141 Molecular Signatures of Cocaine Toxicity in Postmortem Human Brain and Neurons
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: The goal of this project is to identify new therapeutic targets and biomarkers to treat or prevent cocaine toxicity by investigating proteomic, transcriptomic and epigenetic signatures of cocaine exposure in human subjects.
Emily Frances Mendez +6 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate the association between gender‐based violence (GBV) assessed in early pregnancy and adverse perinatal outcomes using relative and absolute effect measures in an urban low‐ and middle‐income setting. Methods We conducted a prospective cohort study including 3890 singleton pregnancies recruited from two public healthcare ...
Elsa Romelia Moreno‐Verduzco +6 more
wiley +1 more source
Critical Role of d -Serine Signaling in Synaptic Plasticity Relevant to Cocaine Addiction
, 2017 The fundamental role of d-serine as coagonist at the n-methyl-. d-aspartate receptor (NMDAR), a major glutamate receptor subtype involved in synaptic plasticity, is well documented and experimental evidence indicates now that this d-amino acid is an ...
Mainardi, M. +8 more
core +2 more sources
Reduced cue-induced reinstatement of cocaine-seeking behavior in Plcb1 +/− mice
Translational Psychiatry, 2021 Cocaine addiction causes serious health problems, and no effective treatment is available yet. We previously identified a genetic risk variant for cocaine addiction in the PLCB1 gene and found this gene upregulated in postmortem brains of cocaine abusers
Judit Cabana-Domínguez +5 more
doaj +1 more source
Cocaine-induced conditioned taste aversions: Investigations of neurochemical mediation
, 2012 Drugs of abuse have both rewarding and aversive effects, and it is the balance of these effects which impact abuse vulnerability. Although research has traditionally focused on the rewarding effects of drugs, their aversive effects have recently gained ...
Katherine M. Serafine (16757310)
core +1 more source
Journal of Addictions &Offender Counseling, EarlyView.ABSTRACT This study reports findings from a community‐based program evaluation examining treatment effectiveness in a real‐world outpatient substance use care setting. Using a within‐program pre–post design, changes in alcohol and drug use were assessed among clients receiving intensive outpatient services.
Jessie A. Brown +3 more
wiley +1 more source
Addictive Behaviors Reports, 2019 Objectives: Cocaine use is increasing and many cocaine users engage in polysubstance use. Within polysubstance use, relationships among use of individual substances are necessarily complex.
Yiyang Liu +4 more
doaj +1 more source
JCPP Advances, EarlyView.Abstract Background Future time perspective dimensions have been linked to various mental illnesses. Given the tendency for mental illnesses to co‐occur, it is necessary to disentangle associations between future‐oriented constructs and shared versus symptom‐domain‐specific psychopathology.
Yi Yang +6 more
wiley +1 more source