Results 111 to 120 of about 47,059 (243)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

The Influence of Oral Health Related Knowledge, Attitudes and Practices on Oral Health Risk‐Related Behaviours of People in Custodial Settings: An Integrative Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the influence of oral health‐related knowledge, attitudes and practices on oral health risk‐related behaviours of people in custodial settings. Design Integrative review. Data Sources Scopus, ProQuest Central, Web of Science, Medline, CINAHL, Academic Search Complete, PsycINFO and Education Research Complete were searched in ...
Izabella Barak, Brandon W. Smith, Ajesh George, Rebecca Bosworth, Della Maneze, Kate Inderwisch, Yenna Salamonson   +6 more
wiley   +1 more source

Type and developmental timing of childhood adversity predicts psychopathology symptoms in a South African birth cohort

Journal of Child Psychology and Psychiatry, EarlyView.
Background Childhood adversity is widespread globally and is one of the strongest predictors of later psychopathology. However, the differential effects of type and timing of childhood adversities on childhood psychopathology remain unclear, highlighting the need to explore which life‐course hypotheses (sensitive periods, accumulation of exposure, and ...
Sherief Y. Eldeeb, Brooke G. McKenna, Marilyn T. Lake, Nadia Hoffman, Alexandre A. Lussier, Esther Walton, Andrew J. Simpkin, Andrew D.A.C. Smith, Heather J. Zar, Dan J. Stein, Erin C. Dunn   +10 more
wiley   +1 more source

Associations between prenatal alcohol exposure and parent‐reported sleep disturbances in 10,336 adolescents: an Adolescent Brain Cognitive Development study

Journal of Child Psychology and Psychiatry, EarlyView.
Background This study investigated the associations between prenatal alcohol exposure (PAE), including low and moderate levels of exposure, and parent‐reported sleep disturbances during adolescence. This is an area that remains understudied despite evidence linking PAE, particularly heavy PAE, to poor sleep in younger children and the growing ...
Emma K. Devine, ReJoyce Green, Rachel Visontay, Hollie Byrne, Julia Riches, Elizabeth J. Elliott, Nicola C. Newton, Lindsay M. Squeglia, Louise Mewton, Lexine A. Stapinski   +9 more
wiley   +1 more source

Commentary on Zacher et al.: How cocaine memories may drive craving and drug instrumentalization

Addiction, EarlyView.
Christian P. Müller
wiley   +1 more source

3D transparent technology displays the developmental patterns of ductus arteriosus morphology in chicken embryos before and after birth

Journal of Anatomy, EarlyView.
At the eighth week of human embryonic development, 3D transparent imaging enables clear visualization of the outflow tract's morphological features, revealing its anatomical components in detail. Abstract The ductus arteriosus (DA) is a critical fetal vascular structure that shunts blood from the pulmonary artery to the aorta, bypassing the non ...
Conghong Xu, Lidi Li, Xiu Wu, Yanli Zhang, Chuanye Wu, Juan Chen, Haihua Gao, Zhenglai Ma   +7 more
wiley   +1 more source

The Role of Religious Belief and Sentencing Decisions in a UK Sample

Journal of Personality, EarlyView.
ABSTRACT Objective This is a stage 1 registered report submission that seeks to examine whether religious belief and a range of other individual differences variables are associated with youth justice preferences. Method As this is a stage 1 registered report, these are liable to change.
Isaac Halstead, Alex Lloyd
wiley   +1 more source

Veterinary Pharmaceutical Safety Competencies for New Graduates: Description of an Interprofessional Simulated Learning Activity

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The misuse and abuse of veterinary anesthetic and analgesic agents pose significant public health risks, particularly with the growing presence of ultrapotent opioids and other anesthetics in the illicit drug trade. In response, there is increasing emphasis on incorporating medication safety training into veterinary curricula.
Margene Anderson, Carrie Schroeder, Kristopher M. Schroeder   +2 more
wiley   +1 more source