Results 91 to 100 of about 15,480,873 (292)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Cocaine Production and Trafficking: What do we know? [PDF]

The main purpose of this chapter is to summarize the information currently available on cocaine production and trafficking. The chapter starts by describing the available data on cocaine production and trade, the collection methodologies, (if available ...
Daniel Mejía, Carlos Esteban Posada
core   +2 more sources

The Impact of Maternal Alcohol and Illicit Drug Use on Children's Behavior Problems: Evidence from the Children of the National Longitudinal Survey... [PDF]

This study uses data from the Children of the National Longitudinal Survey of Youth to test for evidence of a causal relationship between maternal alcohol use, marijuana use and cocaine use, and children's behavior problems.
Sara Markowitz, Pinka Chatterji
core  

Opportunities and Alliances: The Relational Dynamics of Criminal Collusion in Latin America

The British Journal of Sociology, EarlyView.
ABSTRACT Based on ethnographic fieldwork in Mexico and judicial wiretap analysis in Argentina, this paper shows that collusion between state actors and violent non‐state actors operates through fluid and competitive relational networks rather than stable hierarchies or fixed institutional arrangements.
Eldad J. Levy, Javier Auyero
wiley   +1 more source

Differences in Risk Factors for Severe Preeclampsia and HELLP Syndrome in Singleton Versus Twin Pregnancies: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine whether the associations between pre‐pregnancy risk factors and severe preeclampsia/eclampsia (SPE) and/or HELLP syndrome differ between singleton and twin pregnancies. Design A population‐based retrospective cohort study. Setting British Columbia (BC), Canada.
Mackenzie Campbell, Johanna Koegl, Jeffrey N. Bone, Sofia Nicolls, Janet Lyons, Chantal Mayer, Kenneth I Lim, Julie Van Schalkwyk, K. S. Joseph, Sarka Lisonkova, the ORQA group, A. Christoffersen‐Deb, S. Derikvand, S. John, L. Richter, M. Rougerie, Y. Sabr, M. Vidler   +17 more
wiley   +1 more source

Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review

Frontiers in Psychiatry, 2018
Background: Despite advances in behavioral and pharmacotherapy interventions, substance use disorders (SUDs) are frequently refractory to treatment.
Jennifer L. Jones, Camilo F. Mateus, Robert J. Malcolm, Kathleen T. Brady, Kathleen T. Brady, Sudie E. Back, Sudie E. Back   +6 more
doaj   +1 more source

Comorbidities in patients with cocaine use disorders

Journal of Substance Use
Since cocaine use is associated with a wide range of mental disorders, early detection of these comorbidities, coupled with a more accurate characterization of these groups, is essential if treatment prognosis is to be improved. A multicenter, prospective cross-sectional study with 337 cocaine or crack users, treated at outpatient addiction units.
Karina Jiménez-Silvestre, Solveig E. Rodríguez-Kuri, Carmen Fernández-Cáceres, Rodrigo Marín-Navarrete   +3 more
openaire   +1 more source

'I'd a wife and two kids. Everything looked perfect to the outside world. It wasn't. I was addicted to cocaine'.

, 2018
A middle-class family brought to the brink by a father’s cocaine use speak about an addiction that cross all demographics......
Murray, Sean
core  

Forensic challenges in a case of suspected filicide, matricide, and post‐mortem dismemberment

Journal of Forensic Sciences, EarlyView.
Abstract Familicide represents one of the most complex forms of domestic violence in forensic practice. Among intrafamilial homicides, filicide and matricide pose major medico‐legal and criminological challenges, particularly when autopsy findings are nonspecific or severely altered by post‐mortem changes.
Isabella Caristo, Rosario Barranco, Giulio Fraternali Orcioni, Domenico Coviello, Francesco Ventura   +4 more
wiley   +1 more source

From Conflicting Outcomes to Mutual Losses: How Punitive Responses to Problematic Substance Use Suppress Help‐Seeking and Cause Harm

Human Resource Management Journal, EarlyView.
ABSTRACT Problematic substance use (PSU) is a significant, inadequately managed people management challenge. Drawing on the conflicting outcomes and mutual losses perspectives on HRM and employee wellbeing, and using Job Demands‐Resources theory to explain underlying strain‐driven loss cycles, we examine factors shaping PSU and help‐seeking among 575 ...
Karen Maher, Aoife M. McDermott, Andrew Clements, Emmert Roberts, Sally Pezaro   +4 more
wiley   +1 more source