Results 81 to 90 of about 47,059 (243)

Comorbidities in patients with cocaine use disorders

Journal of Substance Use
Since cocaine use is associated with a wide range of mental disorders, early detection of these comorbidities, coupled with a more accurate characterization of these groups, is essential if treatment prognosis is to be improved. A multicenter, prospective cross-sectional study with 337 cocaine or crack users, treated at outpatient addiction units.
Karina Jiménez-Silvestre, Solveig E. Rodríguez-Kuri, Carmen Fernández-Cáceres, Rodrigo Marín-Navarrete   +3 more
openaire   +1 more source

Impulsiveness as a predictor of topiramate response for cocaine use disorder

The American Journal on Addictions, 2019
Background/ObjectivesTopiramate has been studied in the treatment of substance use disorders and is often used off‐label in the treatment of other disorders with impaired impulse control. We sought to determine whether impulsiveness could predict topiramate treatment response in individuals with cocaine use disorder (CUD).MethodsIn a post‐hoc analysis ...
Derek, Blevins, Xin-Qun, Wang, Sana, Sharma, Nassima, Ait-Daoud   +3 more
openaire   +3 more sources

Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

Addiction, EarlyView.
Abstract Background and aims Evidence regarding the impacts of supervised drug consumption services (SDC) remains mixed, and few evaluations have used individual‐level, linkable health data to examine service withdrawal. In September 2024, the Red Deer overdose prevention site (OPS) in Alberta, Canada, was scheduled for closure, with operations ceasing
Nathaniel Day, Kym Kaufmann, Daniel John Alexander Devoe, Vanja Grubac, Alessia DiMarzo, Haisa Osmanli, Vanessa Norton, Shelly Vik, Nickie Mathew, Robert Lawrence Tanguay, Anees Bahji   +10 more
wiley   +1 more source

Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement

Frontiers in Genetics, 2016
Despite evidence of substantial comorbidity between psychiatric disorders and substance involvement, the extent to which common genetic factors contribute to their co-occurrence remains understudied.
Caitlin E Carey, Arpana Agrawal, Kathleen K Bucholz, Sarah M Hartz, Michael T Lynskey, Elliot C Nelson, Laura J Bierut, Ryan Bogdan   +7 more
doaj   +1 more source

A call for action: Closing the evidence gap in management of stimulant‐induced psychosis

Addiction, EarlyView.
Abstract Background Stimulant‐induced psychosis (StIP) is emerging as one of most pressing health challenges. Over the past two decades, stimulant‐related harms and psychiatric care demands have risen sharply. Individuals with StIP often present with severe agitation and high suicide risk, and up to half progress to chronic psychotic illness within two
Anne Bouthillier, Heidar Sharafi, Adam Bisaga, Didier Jutras‐Aswad   +3 more
wiley   +1 more source

Impact of SMAASH-C, a novel nutritional supplement, on drug-seeking and toxicity in female and male rats

Translational Psychiatry
Relapse to drug use after abstinence is a major challenge in treating substance use disorder. Exposure to drug-associated cues during abstinence can trigger intense craving and precipitate relapse.
Eleanor Blair Towers, Ivy L. Williams, Ariadne S. K. Aristidou, Ajibike O. Salako-Akande, Wendy J. Lynch   +4 more
doaj   +1 more source

The Effects of Excitatory and Inhibitory Social Cues on Cocaine-Seeking Behavior

Frontiers in Behavioral Neuroscience, 2016
Social partners influence the likelihood of using drugs, developing a substance use disorder, and relapse to drug use after a period of abstinence. Preclinical studies report that social cues influence the acquisition of cocaine use, the escalation of ...
Mark Andrew Smith, Huailin Zhang, Andrea Maureen Robinson   +2 more
doaj   +1 more source

The association between sleep disturbance and stimulant use: A cross‐lagged examination

Addiction, EarlyView.
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian, Renae D. Schmidt, Daniel J. Feaster, Rui Duan, Sophia T. Gonzalez, Kathryn Hefner, Dikla Shmueli‐Blumberg, Ashley Vena, Landhing M. Moran, Chloe A. DiCamillo, Shirin Shafazand, Susan Tross, Judith Feinberg   +12 more
wiley   +1 more source

The evolution of Australian cannabis policies, 1967 to 2024

Addiction, EarlyView.
Abstract Aim To describe the outcomes of cannabis policy debates in Australia from 1967 to 2024. Methods We searched popular media, public reports, parliamentary inquiries and policy documents on cannabis in Australia since the 1960s and examined peer reviewed papers, national survey data and police records of cannabis‐related arrests.
Wayne D. Hall, Danielle Dawson, Ben Johnson, Tesfa M. Yimer   +3 more
wiley   +1 more source

Patient‐reported outcomes for monitoring substance use treatment: A systematic review of single‐item measures

Addiction, EarlyView.
Abstract Background and aims Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (
Thomas J. Reese, Hilary A. Tindle, Justin Bachmann, Adam Wright, Jessica S. Ancker, Carolyn M. Audet, Mauli V. Shah, Bryan D. Steitz, Michael H. Levin, Kristopher A. Kast, David Marcovitz, Amanda von Horn, A. Taylor Kelley, John F. P. Bridges   +13 more
wiley   +1 more source