Results 61 to 70 of about 15,480,873 (292)
ABSTRACT Background Mental health courts divert individuals with serious mental illness away from imprisonment into community‐based treatment and supervision. Early research indicates that such treatment contracts can reduce recidivism and provide various other benefits. Aspects of eligibility for this diversion option are still under‐researched.
Steven Keener, Audrey Morrison
wiley +1 more source
A novel delta opioid receptor specific peptide reduces craving in an animal model of cocaine seeking
Substance use disorder, and particularly cocaine use disorder, is a complex disease that affects societal, economic, and psychological factors. Endogenous β-endorphin released after prolonged cocaine withdrawal has been reported to activate the accumbal ...
Pnina Shirel Itzhak-Israeli +13 more
doaj +1 more source
Acute health problems due to recreational drug use in patients presenting to an urban emergency department in Switzerland [PDF]
QUESTIONS UNDER STUDY: To describe acute toxicity of recreational drugs including novel psychoactive substances. METHODS: We included all cases presenting at the emergency department (ED) of the University Hospital of Basel, Switzerland, between ...
Dolder, Patrick C. +9 more
core +2 more sources
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen +7 more
wiley +1 more source
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai +12 more
wiley +1 more source
Estimating Illicit Stimulant Drug Consumption in Luxembourg Using Wastewater‐Based Epidemiology
Wastewater‐based epidemiology provided nationwide estimates of illicit stimulant consumption in Luxembourg, revealing higher urban use, weekend increases in cocaine and MDMA, and cocaine as the dominant stimulant. The approach offers an objective complement to conventional drug surveillance for informing public health and policy.
Nadine Berndt +5 more
wiley +1 more source
KOR agonists for the treatment and/or prevention of opioid use disorder and cocaine use disorder. [PDF]
Reports in the 1990s and 2000s showed that kappa opioid receptor (KOR) agonists might be promising for treatment and/or prevention of opioid use disorder (OUD) and cocaine use disorder (CUD). However, the side effects associated with KOR agonists available at the time, such as psychotomimesis, dysphoria and sedation, prevented clinical development ...
Liu-Chen LY, Huang P.
europepmc +3 more sources
Cocaine craving and use during pharmacotherapy trials for cocaine use disorder: A multi-trajectory analysis. [PDF]
There is limited research on the course of drug craving in treatment trials of stimulant use disorders. This study examined trajectories of cocaine craving and use and their associations with other outcomes of cocaine use disorder in pharmacotherapy trials of cocaine use disorder.In 1070 participants from 6 randomized controlled trials testing ...
Mojtabai R +7 more
europepmc +3 more sources
Drug fluency: A potential marker for cocaine use disorders [PDF]
The goal of the current study was to tailor semantic fluency to increase its sensitivity and ecological validity in the study of drug use disorders. On a newly modified "drug" fluency task, individuals with cocaine use disorders who tested positive for cocaine at study day named more drug-related words than control subjects.
R Z, Goldstein +4 more
openaire +2 more sources
Cocaine use by the well-off is fuelling violent crime, say gardaí.
A huge increase in cocaine use in Ireland and Europe is being driven by employed middle and upper class people who believe it is acceptable to use the drug without taking any responsibility for the organised crime associated with it, according to gardaí.
Reynolds, Paul
core

