ABSTRACT Introduction Gabapentin is widely prescribed off‐label to treat pain. However, there are concerns about the proliferation of medical and non‐medical use, and the potential increased risk of overdose death associated with concurrent opioid use.
Evelyne Marie Piret +7 more
wiley +1 more source
Pregnenolone reduces provoked craving and cocaine use in men and women with cocaine use disorder: A pilot trial. [PDF]
Sakmar E +5 more
europepmc +1 more source
The Detection of Novel Nitazene‐Class Opioids in Unregulated Drug Markets in Canada
ABSTRACT Introduction Nitazenes, a highly potent class of synthetic opioids, have emerged in Canadian unregulated drug markets. We report on their presence and composition, along with overdose trends. Methods Samples were obtained from January 2019 to July 2024 from two drug checking services (Toronto's Drug Checking Service (TDCS) and drug checking ...
Emily A. Gelgoot +12 more
wiley +1 more source
Exploring the Role of Reward Functioning in the Overlap of Post-Traumatic Stress and Cocaine Use Disorder. [PDF]
Hull K +7 more
europepmc +1 more source
ABSTRACT Introduction In addition to their use as opioid agonist therapy (OAT), methadone and buprenorphine/naloxone also have analgesic properties. However, there is limited information on the relative effectiveness of these medications for analgesia in the context of treatment for non‐heroin opioid use disorder (OUD).
Katie Lyman +5 more
wiley +1 more source
Independence of Peripheral Brain-Derived Neurotrophic Factor from Depression and Anxiety Symptoms in Cocaine Use Disorder: An Initial Description. [PDF]
Islas-Preciado DM +8 more
europepmc +1 more source
Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta‐Analysis
ABSTRACT Issues Alcohol use disorder (AUD) shows sex‐related differences in prevalence, harm and treatment response. Despite growing interest in sex differences, evidence synthesis evaluating pharmacotherapy effectiveness by sex remains limited. Approach Web of Science, PubMed, Scopus, PsycINFO and Cochrane were searched twice.
Juliette Allen +11 more
wiley +1 more source
Brain connectomics markers for response prediction to transcranial magnetic stimulation in cocaine use disorder. [PDF]
Ghazi N +2 more
europepmc +1 more source
ABSTRACT Introduction This study examined the prevalence and associations of personality dysfunction and antisociality among youth accessing residential substance use disorder (SUD) withdrawal. Methods Participants were 100 youth (57% female) aged 18–25 scheduled or admitted to residential SUD withdrawal in Victoria, Australia.
Nathan Akoka +12 more
wiley +1 more source
The role of Iowa gambling task performance in response to citalopram treatment for cocaine use disorder. [PDF]
de Dios C +6 more
europepmc +1 more source

