Results 201 to 210 of about 47,059 (243)

Cocaine Use Disorders and Serum Magnesium Profile

Neuropsychobiology, 2009
<i>Introduction:</i> Magnesium influences the nervous system via its actions on the release and metabolism of neurotransmitters, and abnormal magnesium metabolism has been implicated in several neuropsychiatric disorders with prominent mood symptoms.
Tonioni, Federico, Martinotti, Giovanni, Barra, Andrea, Martinelli, David, Autullo, Gianna, Rinaldi, Federica, Tedeschi, Daniela, Janiri, Luigi, Bria, Pietro   +8 more
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Medications to treat cocaine use disorders

Current Opinion in Psychiatry, 2019
Cocaine is a highly addictive substance with serious medical and mental health consequences. Despite these concerns, there are no Food and Drug Administration-approved medications for the treatment of cocaine use disorder (CUD). Although many medication-assisted treatments (MATs) have been investigated, no clear guidelines exist for clinicians treating
Jonathan, Buchholz, Andrew J, Saxon
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Peripheral toxicity in crack cocaine use disorders

Neuroscience Letters, 2013
A growing body of evidence suggests that crack cocaine misuse has widespread systemic and cognitive consequences, but little attention has been given to its systemic pathophysiology. We report here changes in inflammation markers, oxidative damage and brain derived neurotrophic factor in a sample of outpatients with crack cocaine use disorders.
Joana C M, Narvaez, Pedro V, Magalhães, Gabriel R, Fries, Gabriela D, Colpo, Letícia S, Czepielewski, Priscila, Vianna, José Artur Bogo, Chies, Adriane R, Rosa, Lisia, Von Diemen, Eduard, Vieta, Flávio, Pechansky, Flávio, Kapczinski   +11 more
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Electrocardiographic characteristics in individuals with cocaine use disorder

The American Journal on Addictions, 2017
Background and ObjectivesChronic cocaine use has been linked to several abnormalities in cardiac functioning. The objective of this study was to further characterize baseline heart rate and electrocardiograph (ECG) profiles of individuals with cocaine use disorder (CUD) by evaluating demographic and drug use variables that may impact cardiovascular ...
James J. Mahoney, Colin N. Haile, Richard De La Garza, Harsh Thakkar, Thomas F. Newton   +4 more
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Reinforcer pathology in cocaine use disorder: Temporal window determines cocaine valuation

Drug and Alcohol Dependence, 2021
The Experimental Medicine Approach offers a unique perspective to determine clinical behavior change by engaging a target underlying the cause of a disorder. The present work engaged a novel target of addiction, Reinforcer Pathology, in two studies to test changes in behavior among individuals with cocaine use disorder.In Study 1, n = 44 participants ...
Sarah E, Snider, Jamie K, Turner, Samuel M, McClure, Warren K, Bickel   +3 more
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Lifetime Severity Index for Cocaine Use Disorder (LSI-Cocaine)

The Journal of Nervous & Mental Disease, 1999
We developed a lifetime severity index for cocaine use disorder and examined its predictive validity of posttreatment outcome using data from the national Drug Abuse Treatment Outcome Study. The index, based on 28 items, considered frequency of use, recency, dependency, and attempt to quit.
Y, Hser, H, Shen, C, Grella, M D, Anglin
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Experimental Medications for Cocaine Use Disorder

2021
Many medication studies for cocaine use disorder have not been found efficacious. Disulfiram has demonstrated effectiveness for cocaine use disorder in several studies. Before starting disulfiram, patients must be alcohol free and monitored for the risk of liver injury.
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The limited impact that cocaine use patterns have on neurocognitive functioning in individuals with cocaine use disorder

Journal of Psychopharmacology, 2017
It is well-documented in the literature that cocaine use is associated with neurocognitive impairment. The manner in which patterns of cocaine use, such as years of use, recent use over the past month, and daily amount of cocaine use, moderate neurocognition has been studied in a relatively piecemeal manner.
James J, Mahoney, Ari D, Kalechstein, Thomas F, Newton, Richard, De La Garza   +3 more
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Assessing cognitive functioning in individuals with cocaine use disorder

Journal of Clinical and Experimental Neuropsychology, 2017
There have been mixed findings assessing the impact of regular cocaine use on cognitive functioning. This study employed a comprehensive cognitive battery to compare the performance of individuals diagnosed with a cocaine use disorder (N = 3 abusers, N = 17 dependent) against the performance of two control groups: (a) non-drug-users, and (b) marijuana ...
Kirsten M, Frazer, Jennifer J, Manly, Geraldine, Downey, Carl L, Hart   +3 more
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Disorders relating to the use of amphetamine and cocaine

2012
Abstract Amphetamine and cocaine are classed as stimulant drugs, although the distinction between stimulants and depressants can be criticized on the grounds that the same drug may have both actions in turn. This does indeed occur with amphetamine and cocaine, but the initial desired effects are increased energy and activity, and ...
Nicholas Seivewright, Robert Fung
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