Results 1 to 10 of about 72,451 (254)

Mechanisms of sensorineural cell damage, death and survival in the cochlea [PDF]

Frontiers in Aging Neuroscience, 2015
The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ann C Y Wong, Allen F Ryan
exaly   +3 more sources

Development of the cochlea [PDF]

Development, 2020
ABSTRACT The cochlea, a coiled structure located in the ventral region of the inner ear, acts as the primary structure for the perception of sound. Along the length of the cochlear spiral is the organ of Corti, a highly derived and rigorously patterned sensory epithelium that acts to convert auditory stimuli into neural impulses.
Elizabeth Carroll Driver, Matthew W. Kelley   +1 more
openaire   +4 more sources

Clinical Validation of Manual Measurement of Cochlea Length With Post‐Operative Electrode Insertion Depth: A Pilot Study [PDF]

Laryngoscope Investigative Otolaryngology
Objective To clinically validate manual measurement of cochlear length from pre‐operative image of cochlea with post‐operative image of cochlear implant (CI) electrode.
Fei Wang, Dharmikkumar Anaghan, Anandhan Dhanasingh, Lian Hui   +3 more
doaj   +2 more sources

Molecular heterogeneity of the non-human primate cochlea [PDF]

Nature Communications
Unraveling the intricate composition and function of the cochlea is paramount to comprehending the mechanisms underlying sound perception and the pathogenesis of auditory disorders.
Xin Chen, Yuwei Che, Jieyu Qi, Ming Cen, Shan Gao, Bin Zhu, Yiheng Ao, Xiangyu Ma, Cheng Cheng, Rongrong Guo, Xinlin Wang, Tian Shen, Jiheng Wu, Fanliang Kong, Wei Si, Yongchang Chen, Tao Tan, Ling Lu, Renjie Chai   +18 more
doaj   +2 more sources

Application of Curved MPR Algorithm to High Resolution 3 Dimensional T2 Weighted CISS Images for Virtual Uncoiling of Membranous Cochlea as an Aid for Cochlear Morphometry [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: With the use of various surgical techniques, types of implants, the preoperative assessment of cochlear dimensions is becoming increasingly relevant prior to cochlear implantation.
Joish Upendra Kumar, Y Kavitha
doaj   +1 more source

Scanning laser optical tomography for in toto imaging of the murine cochlea. [PDF]

PLoS ONE, 2017
The mammalian cochlea is a complex macroscopic structure due to its helical shape and the microscopic arrangements of the individual layers of cells.
Lena Nolte, Nadine Tinne, Jennifer Schulze, Dag Heinemann, Georgios C Antonopoulos, Heiko Meyer, Hans Gerd Nothwang, Thomas Lenarz, Alexander Heisterkamp, Athanasia Warnecke, Tammo Ripken   +10 more
doaj   +1 more source

Identification and Characterization of TMEM119-Positive Cells in the Postnatal and Adult Murine Cochlea

Brain Sciences, 2023
Transmembrane protein 119 (TMEM119) is expressed in a subset of resident macrophage cells of the brain and was proposed as a marker for native brain microglia. The presence of cells expressing TMEM119 in the cochlea has not yet been described.
Mohamed Bassiouni, Alina Smorodchenko, Heidi Olze, Agnieszka J. Szczepek   +3 more
doaj   +1 more source

Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system. [PDF]

PLoS ONE, 2018
Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model.
Tae Hoon Kong, Sunkon Yu, Byungjo Jung, Jin Sil Choi, Young Joon Seo   +4 more
doaj   +1 more source

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

eLife, 2022
Reprogramming of the cochlea with hair-cell-specific transcription factors such as ATOH1 has been proposed as a potential therapeutic strategy for hearing loss.
Amrita A Iyer, Ishwar Hosamani, John D Nguyen, Tiantian Cai, Sunita Singh, Melissa M McGovern, Lisa Beyer, Hongyuan Zhang, Hsin-I Jen, Rizwan Yousaf, Onur Birol, Jenny J Sun, Russell S Ray, Yehoash Raphael, Neil Segil, Andrew K Groves   +15 more
doaj   +1 more source

The Evolution of Bat Vestibular Systems in the Face of Potential Antagonistic Selection Pressures for Flight and Echolocation [PDF]

, 2013
PMCID: PMC3634842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Herrel, A McVean, AJ Drummond, AJ Drummond, AZ Yang, B Turkewitsch, BP Kotler, C Dietz, CM Miller-Butterworth, D Schluter, DK Riskin, DK Riskin, DK Riskin, DR Ketten, DR Warrick, EC Teeling, EC Teeling, ER Seiffert, F Ramprashad, F Spoor, F Spoor, G Billet, G Jones, G Storch, GM Jones, GN Eick, GP Lohmann, H Nishihara, HT Arita, Ibnu Maryanto, J Gatesy, J Habersetzer, James A. Cotton, JD Hadfield, JH Ten Kate, Kalina T. J. Davies, KD Rose, KL Welker, Kornelius Kupczik, KTJ Davies, L Gustafsson, LM Witmer, M Kirkegaard, M Muller, MA Hopkins, MA Larkin, MB Fenton, MD Malinzak, MJ Benton, MS Springer, N Jeffery, N Jeffery, N Jeffery, N MacLeod, N Veselka, NB Simmons, NB Simmons, NV Jennings, P Chevret, P Gunz, Paul J. J. Bates, PD Gingerich, PG Cox, PG Cox, PW Freeman, R David, R Lebrun, RJ Knell, RW Meredith, S Ducrocq, S Nummela, SC Pedersen, SS Horowitz, Stephen J. Rossiter, T Kingston, T Kingston, T Lindenlaub, T Schmelzle, TE Macrini, UM Norberg, UM Norberg, W Graf, WE Johnson, WJ Murphy, X Zhou, Ø Hammer   +85 more
core   +7 more sources