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The Mechanism of the Cochlea [PDF]

open access: bronzeNature, 1922
IF I understand Dr. Perrett's letter in NATURE of November 11, p. 633, his objection to Yoshii's experiments (which would apply equally to those of Wittmaack and Siebenmann) is based on the assumption that the intensity of the stimulation of every part of the cochlea must be proportional to the amplitude of the vibration set up in that part.
G. Wilkinson
  +11 more sources

Development of the cochlea [PDF]

open access: yesDevelopment, 2020
ABSTRACT The cochlea, a coiled structure located in the ventral region of the inner ear, acts as the primary structure for the perception of sound. Along the length of the cochlear spiral is the organ of Corti, a highly derived and rigorously patterned sensory epithelium that acts to convert auditory stimuli into neural impulses.
Elizabeth Carroll Driver   +1 more
openaire   +4 more sources

Meniere's disease: Structural considerations in early cochlea hydrops [PDF]

open access: yesLaryngoscope Investigative Otolaryngology
Objective Structural features of the human cochlea may control early lesion formation in endolymphatic hydrops. This process may hinge on three structural features: the flattened spiral shape of the human cochlea, the toroidal configuration of the ...
Daniel J. Pender
doaj   +2 more sources

Application of Curved MPR Algorithm to High Resolution 3 Dimensional T2 Weighted CISS Images for Virtual Uncoiling of Membranous Cochlea as an Aid for Cochlear Morphometry [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: With the use of various surgical techniques, types of implants, the preoperative assessment of cochlear dimensions is becoming increasingly relevant prior to cochlear implantation.
Joish Upendra Kumar, Y Kavitha
doaj   +1 more source

Scanning laser optical tomography for in toto imaging of the murine cochlea. [PDF]

open access: yesPLoS ONE, 2017
The mammalian cochlea is a complex macroscopic structure due to its helical shape and the microscopic arrangements of the individual layers of cells.
Lena Nolte   +10 more
doaj   +1 more source

Identification and Characterization of TMEM119-Positive Cells in the Postnatal and Adult Murine Cochlea

open access: yesBrain Sciences, 2023
Transmembrane protein 119 (TMEM119) is expressed in a subset of resident macrophage cells of the brain and was proposed as a marker for native brain microglia. The presence of cells expressing TMEM119 in the cochlea has not yet been described.
Mohamed Bassiouni   +3 more
doaj   +1 more source

Variations in cochlea shape reveal different evolutionary adaptations in primates and rodents

open access: yesScientific Reports, 2023
The presence of a coiled cochlea is a unique feature of the therian inner ear. While some aspects of the cochlea are already known to affect hearing capacities, the full extent of the relationships between the morphology and function of this organ are ...
Joaquin del Rio   +3 more
doaj   +1 more source

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

open access: yeseLife, 2022
Reprogramming of the cochlea with hair-cell-specific transcription factors such as ATOH1 has been proposed as a potential therapeutic strategy for hearing loss.
Amrita A Iyer   +15 more
doaj   +1 more source

Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system. [PDF]

open access: yesPLoS ONE, 2018
Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model.
Tae Hoon Kong   +4 more
doaj   +1 more source

Steady streaming as a method for drug delivery to the inner ear

open access: yesScientific Reports, 2021
The inner ear, or cochlea, is a fluid-filled organ housing the mechanosensitive hair cells. Sound stimulation is relayed to the hair cells through waves that propagate on the elastic basilar membrane.
Laura Sumner   +2 more
doaj   +1 more source

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