Development of the cochlea [PDF]
ABSTRACT The cochlea, a coiled structure located in the ventral region of the inner ear, acts as the primary structure for the perception of sound. Along the length of the cochlear spiral is the organ of Corti, a highly derived and rigorously patterned sensory epithelium that acts to convert auditory stimuli into neural impulses.
Elizabeth Carroll Driver+1 more
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RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors [PDF]
Background: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution.
Hortensia Sanchez-Calderon+6 more
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The Mechanism of the Cochlea [PDF]
IF I understand Dr. Perrett's letter in NATURE of November 11, p. 633, his objection to Yoshii's experiments (which would apply equally to those of Wittmaack and Siebenmann) is based on the assumption that the intensity of the stimulation of every part of the cochlea must be proportional to the amplitude of the vibration set up in that part.
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Design of a silicon cochlea system with biologically faithful response [PDF]
This paper presents the design and simulation results of a silicon cochlea system that has closely similar behavior as the real cochlea. A cochlea filter-bank based on the improved three-stage filter cascade structure is used to model the frequency ...
Enemali, Godwin+5 more
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Development of the stria vascularis and potassium regulation in the human fetal cochlea : insights into hereditary sensorineural hearing loss [PDF]
Sensorineural hearing loss (SNHL) is one of the most common congenital disorders in humans, afflicting one in every thousand newborns. The majority is of heritable origin and can be divided in syndromic and nonsyndromic forms. Knowledge of the expression
Chuva de Sousa Lopes, Susana Marina+5 more
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An analog electronic cochlea [PDF]
An analog electronic cochlea has been built in CMOS VLSI technology using micropower techniques. The key point of the model and circuit is that a cascade of simple, nearly linear, second-order filter stages with controllable Q parameters suffices to capture the physics of the fluid-dynamic traveling-wave system in the cochlea, including the effects of ...
Lyon, Richard F., Mead, Carver
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E-ABR in patients with cochlear implant: A comparison between patients with malformed cochlea and normal cochlea [PDF]
OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to ...
de Lucia A.+7 more
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Synchronization of a Nonlinear Oscillator: Processing the Cf Component of the Echo-Response Signal in the Cochlea of the Mustached Bat [PDF]
Cochlear microphonic potential (CM) was recorded from the CF2 region and the sparsely innervated zone (the mustached bat's cochlea fovea) that is specialized for analyzing the Doppler-shifted echoes of the first-harmonic (~61 kHz) of the constant ...
,+5 more
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Patterning of the mammalian cochlea [PDF]
The mammalian cochlea is sophisticated in its function and highly organized in its structure. Although the anatomy of this sense organ has been well documented, the molecular mechanisms underlying its development have remained elusive. Information generated from mutant and knockout mice in recent years has increased our understanding ...
Raquel Cantos+4 more
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Peter Dallas Auditory Physiology Laboratory (The Hugh Knowles Center) and Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois 60208 The cochlea is a hydromechanical frequency analyzer located in the inner ear (Fig. 1 a).
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