Mechanisms of sensorineural cell damage, death and survival in the cochlea [PDF]
Frontiers in Aging Neuroscience, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ann C Y Wong, Allen F Ryan
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Application of Curved MPR Algorithm to High Resolution 3 Dimensional T2 Weighted CISS Images for Virtual Uncoiling of Membranous Cochlea as an Aid for Cochlear Morphometry [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: With the use of various surgical techniques, types of implants, the preoperative assessment of cochlear dimensions is becoming increasingly relevant prior to cochlear implantation.
Joish Upendra Kumar, Y Kavitha
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Scanning laser optical tomography for in toto imaging of the murine cochlea. [PDF]
PLoS ONE, 2017 The mammalian cochlea is a complex macroscopic structure due to its helical shape and the microscopic arrangements of the individual layers of cells.
Lena Nolte +10 more
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Brain Sciences, 2023 Transmembrane protein 119 (TMEM119) is expressed in a subset of resident macrophage cells of the brain and was proposed as a marker for native brain microglia. The presence of cells expressing TMEM119 in the cochlea has not yet been described.
Mohamed Bassiouni +3 more
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eLife, 2022 Reprogramming of the cochlea with hair-cell-specific transcription factors such as ATOH1 has been proposed as a potential therapeutic strategy for hearing loss.
Amrita A Iyer +15 more
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Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system. [PDF]
PLoS ONE, 2018 Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model.
Tae Hoon Kong +4 more
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Variations in cochlea shape reveal different evolutionary adaptations in primates and rodents
Scientific Reports, 2023 The presence of a coiled cochlea is a unique feature of the therian inner ear. While some aspects of the cochlea are already known to affect hearing capacities, the full extent of the relationships between the morphology and function of this organ are ...
Joaquin del Rio +3 more
doaj +1 more source
The Evolution of Bat Vestibular Systems in the Face of Potential Antagonistic Selection Pressures for Flight and Echolocation [PDF]
, 2013 PMCID: PMC3634842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Herrel +85 more
core +7 more sources
Design of a silicon cochlea system with biologically faithful response [PDF]
, 2015 This paper presents the design and simulation results of a silicon cochlea system that has closely similar behavior as the real cochlea. A cochlea filter-bank based on the improved three-stage filter cascade structure is used to model the frequency ...
Enemali, Godwin +5 more
core +1 more source
Modeling cochlear micromechanics: hypotheses and models
Journal of Bio-X Research, 2019 . The cochlea plays an important role in the mammalian auditory system. Sound-induced cell motion in the cochlea is transformed into electrical signals that are then sent to primary auditory neurons.
Guangjian Ni +6 more
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