Results 131 to 140 of about 36,767 (171)

Actigraphy‐based assessment of circadian rhythmicity and sleep in patients with Usher syndrome type 2a: A case–control study

open access: yesJournal of Sleep Research, EarlyView.
Patients with Usher syndrome type 2a experience significant sleep disturbances, including increased sleep latency, reduced sleep quality and increased variability in sleep efficiency, manifesting independently of the progressive visual impairment. These findings highlight the need to recognize sleep disturbances as a comorbidity, which is a critical ...
Jessie M. Hendricks   +5 more
wiley   +1 more source

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

open access: yesNeurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz   +4 more
wiley   +1 more source

A brief historical perspective of otitis externa in dogs

open access: yesVeterinary Dermatology, EarlyView.
Abstract Background The history of otology and otitis externa (OE) goes back to the earliest days of medicine, with notations made in early Egyptian writings and evolving to our modern‐day textbooks and publications. Conclusions and Clinical Relevance The history of OE in dogs is closely tied to the history of otology and veterinary dermatology, and ...
James Owen Noxon
wiley   +1 more source

Two‐tone suppression between the ultrasounds above and within the hearing range in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Hearing range differs among various species. Ultrasound, which is audible to microbats and dolphins, is inaudible to humans through air conduction. However, it can create an auditory sensation when the stimulation is transmitted through the temporal bone.
Noriko Nagase   +7 more
wiley   +1 more source

Long‐Term Outcomes and Quality of Life of Children With Intracranial Ependymoma Treated With Pencil Beam Scanning Proton Therapy

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Ependymoma is a common brain tumor in children and adolescents. Adjuvant radiation therapy improves prognosis but carries potential toxicity risks, particularly for young patients. Proton therapy (PT) offers better conformal treatments and reduces dose exposure compared to traditional photon radiotherapy.
Eymeric Le Reun   +6 more
wiley   +1 more source

Carrier screening for Alport syndrome: The clinical importance of heterozygosity for pathogenic or likely pathogenetic variants

open access: yesJournal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract Reproductive carrier screening aims to identify individuals at an increased chance of having children affected by genetic conditions. However, testing can also reveal health implications for autosomal or X‐chromosome heterozygotes. One such example is screening for Alport syndrome (COL4A3‐5‐related disease) which is one of the most common ...
Vivienne Souter   +6 more
wiley   +1 more source

Long‐Term Auditory and Speech Outcomes of Cochlear Implantation in Children with IP‐I Malformation

open access: yesThe Laryngoscope, Volume 135, Issue 6, Page 2120-2127, June 2025.
This study aimed to investigate the long‐term auditory and speech outcomes in children with Incomplete Partition Type I (IP‐I) who underwent cochlear implantation (CI) and compared their progress to implanted children with normal cochlea. In this long term follow‐up, children with IP‐Ι had shown continuous improvement in auditory and speech ...
Xianqi Liu   +7 more
wiley   +1 more source

Association of Metabolic Dysfunction‐Associated Steatotic Liver Disease With Sudden Sensorineural Hearing Loss Among Older Adults

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 3, June 2025.
This study investigates the association between MASLD and sudden sensorineural hearing loss (SSNHL) among older adults in Korea. Our findings suggest a potential link between MASLD and an increased risk of SSNHL, emphasizing the need for further research and clinical awareness of this association. ABSTRACT Objectives This study examined the association
Eun Seok Kang   +7 more
wiley   +1 more source

Long‐Term Hearing Outcomes Following Cochlear Implantation in Far Advanced Otosclerosis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 172, Issue 6, Page 2065-2071, June 2025.
Abstract Objective This study aims to evaluate the long‐term auditory performance at 5 years in patients with far advanced otosclerosis (FAO) after cochlear implantation compared to controls. Study Design A retrospective cohort study. Setting This study was conducted at a single tertiary medical center.
Raphaële Quatre   +3 more
wiley   +1 more source

The human intelligence evolved from proximal cis‐regulatory saltations

open access: yesQuantitative Biology, Volume 13, Issue 2, June 2025.
Abstract The divergence rate between the alignable genomes of humans and chimpanzees is as little as 1.23%. Their phenotypical difference was hypothesized to be accounted for by gene regulation. We construct the cis‐regulatory element frequency (CREF) matrix to represent the proximal regulatory sequences for each species.
Xiaojie Li, Jianhui Shi, Lei M. Li
wiley   +1 more source

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