Results 131 to 140 of about 68,534 (265)

Transforming Growth Factor‐β‐Activated Protein 1 (TAK1) Regulates Necroptosis in Age‐Related Hearing Loss

Aging Cell, EarlyView.
TAK1‐mediated necroptotic pathways play an important role in the pathogenesis of ARHL. ABSTRACT Inflammation plays an important role in age‐related hearing loss (ARHL). Transforming growth factor‐β‐activated protein 1 (TAK1), a key factor upstream of inflammatory pathways, mediates various cell death pathways, potentially influencing the survival and ...
Hanjing Wang, Yayun Lv, He Zhao, Zhihong Hao, Xiaoyu Zhai, Yan Wang, Jingjing Qiu, Liang Chen, Jiamin Zhou, Limei Cui, Yan Sun   +10 more
wiley   +1 more source

STUDY ON THE FLECTRICAL RESPONSE OF THE COCHLEA Part. 3

, 1955
M. Toyoshima
openalex   +2 more sources

Intracellular and extracellular dc potentials in the cochlea of the alligator lizard [PDF]

, 1975
Thomas Weiß, D. W. Altmann, Michael J. Mulroy   +2 more
openalex   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, EarlyView.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

BIOCHEMICAL AND HISTOCHEMICAL STUDIES ON ACID MUCOPOLY-SACCHARIDES IN THE COCHLEA OF GUINEA PIGS

, 1967
Hitoshi Saitô
openalex   +2 more sources

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

Cell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai, Kun Huang, Wenrui Li, Tianming Wang, Shen Yue, Zhibin Chen, Guangqian Xing, Qinjun Wei, Jun Yao, Xin Cao   +9 more
wiley   +1 more source

Research progress in modulating the auditory system by the cochlear circadian clock system in response to noise exposure. [PDF]

Front Neurosci
Song X, Cheng M, Gu C, Wang F, Ma K, Wang C, She X, Cui B.   +7 more
europepmc   +1 more source

Receptor synapses without synaptic ribbons in the cochlea of the cat. [PDF]

, 1975
RJ Dunn, D.K. Morest
openalex   +1 more source

Finally, some hope. Communicating systemic aspects of climate‐change mitigation

Curator: The Museum Journal, EarlyView.
Abstract Climate communication, including from museums, often advocates individual lifestyle changes, and while these are necessary, the biggest emissions reductions will come from the systemic transition to renewable energy sources. The importance of this systemic change and its attainability has been under‐communicated in the public discourse ...
Jens Astrup, Zachary B. Massey, Yachao Li, Lucy Popova   +3 more
wiley   +1 more source

Early control of cochlear viral load limits cochlear inflammation and prevents virus-induced sensorineural hearing loss. [PDF]

J Neuroinflammation
Smith MD, Seleme MC, Marquez-Lago T, Chen JW, Mach M, Britt WJ.   +5 more
europepmc   +1 more source