Results 141 to 150 of about 73,190 (256)

Cochlea [PDF]

, 2020
openaire   +1 more source

Dietary Ergothioneine as a Novel Anti‐Aging Nutraceutical: Mechanisms, Bioavailability, and Future Perspectives

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian, Liang Chen, Zhen‐Zhen Dong, Chao Yang   +3 more
wiley   +1 more source

Conservation of Neuron‐Astrocyte Correlated Activity in Developing Sensory Pathways

Glia, Volume 74, Issue 5, May 2026.
Astrocytes and neurons in the superior colliculus exhibit spatiotemporal correlated activity before eye opening. Each neuronal wave is followed by a calcium wave in astrocytes. Spillover of glutamate activates mGluR5 and mGluR3 in astrocytes. ABSTRACT Neurons in developing sensory organs exhibit prolonged burst firing before the onset of sensory ...
Vered Kellner, Patrick Parker, Dongeun Heo, Xuelong Mi, Mikhail Coen, Guoqiang Yu, Gesine Saher, Loyal A. Goff, Dwight E. Bergles   +8 more
wiley   +1 more source

Hypofractionated Spot Scanning Proton Therapy for Head and Neck Mucosal Melanoma: A Retrospective Analysis With Quality‐of‐Life Outcome

Head &Neck, Volume 48, Issue 5, Page 1208-1217, May 2026.
ABSTRACT Objective To evaluate clinical outcomes and quality of life (QOL) following hypofractionated spot‐scanning proton therapy (SSPT) for head and neck malignant mucosal melanoma (HNMM). Methods This retrospective study included 39 patients treated with SSPT (60–64 Gy[RBE] in 15–16 fractions) between 2013 and 2023.
Koichiro Nakajima, Hiromitsu Iwata, Gaku Takano, Daiki Kojima, Yukiko Hattori, Yusuke Tsuzuki, Shuou Sudo, Kensuke Hayashi, Toshiyuki Toshito, Hideo Fukano, Hiroyuki Ogino, Akio Hiwatashi   +11 more
wiley   +1 more source

Investigation Into the Dynamics of the Cupula in the Vestibular Organ of Adult Zebrafish Using Metabolic Glycoengineering

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer, Andrea Jüngst, Verena F. Schöwe, Anne‐Katrin Gronewald, Valentin Wittmann   +4 more
wiley   +2 more sources

Rate of Hearing Loss in Platinum‐Naïve Patients Receiving Immune Checkpoint Inhibitors

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1289-1297, May 2026.
Abstract Objective Hearing loss from immune checkpoint inhibitors (ICIs) has been documented in case reports and case series. We present the largest retrospective study investigating the rate of ICI‐related ototoxicity in a monitored cohort of platinum‐naïve patients. Study Design Retrospective cohort study. Setting Tertiary‐care center.
Kaitlyn A. Brooks, Christopher G. Gidley, Olivia Grimley, Catherine Wang, Shirin Jivani, Dianna Roberts, Aung Naing, Jack Phan, Katherine Hutcheson, Xin Wang, Paul W. Gidley, Marc‐Elie Nader   +11 more
wiley   +1 more source

Migraine Features in Patients With Sudden Sensorineural Hearing Loss

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1263-1269, May 2026.
Abstract Objective To investigate the prevalence of migraine features among patients with sudden sensorineural hearing loss (SSNHL) and evaluate potential clinical associations. Study Design Retrospective survey‐based study. Setting Single institution tertiary care center. Methods 168 adult patients with SSNHL were recruited.
Yalda Yazdani, Ella J. Lee, Amanda Francis, Saharnaz Nedjat, Mehdi Abouzari, Hamid R. Djalilian   +5 more
wiley   +1 more source

From transporter to motor: Evolutionary and structural insights into the emergence of prestin's area‐motor activity in mammals

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Prestin, a member of the SLC26A family, is essential for the electromotility of mammalian outer hair cells, converting voltage changes into mechanical work. In contrast, nonmammalian orthologues function as anion transporters. To investigate the molecular and structural basis of this functional divergence, we performed ancestral sequence ...
Nicolás Fuentes‐Ugarte, Tiaren Ruiz‐Rojas, Felipe Garcia‐Olave, Alvaro Ruiz‐Fernandez, Jose Antonio Garate, Victor Castro‐Fernandez, Raul Araya‐Secchi   +6 more
wiley   +1 more source

Dual mechanisms of supporting cell regeneration in the neonatal mouse cochlea. [PDF]

iScience
Abitbol JM, Matern MS, Billings SE, Yao J, Choi SW, Wang T, Heller S, Cheng AG.   +7 more
europepmc   +1 more source

Congenital CMV and Hearing Loss—How Does it Happen and How to Prevent it

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Congenital cytomegalovirus (cCMV) is found worldwide and significantly contributes to permanent childhood hearing loss. CMV has been known to cause sensorineural hearing loss (SNHL) for more than half a century, and CMV‐related hearing loss has consistently been present in all childhood populations where infants with cCMV have been identified ...
Karen B. Fowler
wiley   +1 more source