Results 131 to 140 of about 47,347 (285)

An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda   +6 more
wiley   +1 more source

Otoacoustic emission (OAE)-based measurement of the functioning of the human cochlea and the efferent auditory system

open access: yes, 2010
The discovery of otoacoustic emissions (OAE) has advanced our understanding of cochlear mechanics and the efferent auditory system. OAE are sounds generated withinnormal cochlea either spontaneously or in response to stimulation.
Mishra, Srikanta Kumar
core  

Perilymph Gusher in Cochlear Implantation Surgery: An Algorithm for Management

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Perilymph leak is considered a major complication of cochlear implantation (CI) surgery and can lead to surgical difficulties and postoperative morbidities. This study is aimed to formulate an algorithm for better management of perilymph leak in cases of CI. Methods This is a retrospective study conducted in our tertiary institute on
Ahmed Abdelmoneim Teaima   +4 more
wiley   +1 more source

FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea

open access: yes, 2002
Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF   +2 more
core  

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

open access: yesIntegrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu   +3 more
wiley   +1 more source

Bilateral Carotid Artery Occlusion and Cochlear Oxidative Stress and Hearing Loss in Rats

open access: yesBasic and Clinical Neuroscience, 2020
Introduction: This study aimed to evaluate the effects of bilateral carotid artery occlusion on cochlear oxidative stress and hearing status in rats. Methods: The rats were divided into two sets. The first set was used for electrophysiological recording (
Hamed Fanaei   +2 more
doaj  

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Distortion product otoacoustic emissions: challenging existing theory

open access: yes, 2010
Distortion product otoacoustic emissions (DPOAE or DP) are generated using two primary tones at frequencies f1 and f2 at levels L1 and L2; the two most prominent DP are cubic distortion products at the frequencies 2f1f2 and 2f2f1.
Perdue, Richard John
core  

Cochlea

open access: yes
Citation: 'cochlea' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10542 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

open access: yesCancer Science, EarlyView.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng   +9 more
wiley   +1 more source

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