Results 161 to 170 of about 50,225 (239)

Exercise prehabilitation for brain health and sensory–cognitive function: Mechanistic insights into brain–body interactions

open access: yesExperimental Physiology, EarlyView.
Abstract This mini review article presents a novel hypothesis for extending exercise prehabilitation into the domains of brain health and cognition. Whilst prehabilitation has been gaining popularity in cancer treatment, conferring significant positive benefits to numerous physiological indicators, including post‐operative infection and hospital length
Helen E. Nuttall   +2 more
wiley   +1 more source

Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes

open access: yesExperimental Physiology, EarlyView.
Abstract The pre‐hearing mouse cochlea undergoes critical periods of spontaneous Ca2+‐dependent activity that spreads across non‐sensory supporting cells and inner hair cells (IHCs). These signals have been shown to regulate not only the refinement of neural circuits along the auditory pathway towards functional maturity, but also the maturation of the
Francesca De Faveri   +2 more
wiley   +1 more source

Sound offset responses become highly informative in the auditory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe   +3 more
wiley   +1 more source

The what, which, when, why and who of Off responses in the auditory system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley   +1 more source

Adeno‐associated virus‐based rescue of Myo7a expression restores hair‐cell function and improves hearing thresholds in a USH1B mouse strain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Shaker‐1 mice, a murine model of Usher 1B syndrome, carry a mutation in the unconventional myosin MYO7A. This results in the progressive loss of the two shortest rows of stereocilia that house the mechanoelectrical transducer (MET) channels in hair cells, leading to deafness shortly after hearing onset.
Ana E. Amariutei   +12 more
wiley   +1 more source

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