Results 21 to 30 of about 107,745 (350)
eLife, 2022 Reprogramming of the cochlea with hair-cell-specific transcription factors such as ATOH1 has been proposed as a potential therapeutic strategy for hearing loss.
Amrita A Iyer +15 more
doaj +1 more source
Monitoring blood-flow in the mouse cochlea using an endoscopic laser speckle contrast imaging system. [PDF]
PLoS ONE, 2018 Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model.
Tae Hoon Kong +4 more
doaj +1 more source
Variations in cochlea shape reveal different evolutionary adaptations in primates and rodents
Scientific Reports, 2023 The presence of a coiled cochlea is a unique feature of the therian inner ear. While some aspects of the cochlea are already known to affect hearing capacities, the full extent of the relationships between the morphology and function of this organ are ...
Joaquin del Rio +3 more
doaj +1 more source
Scientific Reports, 2020 Cells of the immune system are present in the adult cochlea and respond to damage caused by noise exposure. However, the types of immune cells involved and their locations within the cochlea are unclear.
Vikrant Rai +5 more
semanticscholar +1 more source
Modeling cochlear micromechanics: hypotheses and models
Journal of Bio-X Research, 2019 . The cochlea plays an important role in the mammalian auditory system. Sound-induced cell motion in the cochlea is transformed into electrical signals that are then sent to primary auditory neurons.
Guangjian Ni +6 more
doaj +1 more source
Steady streaming as a method for drug delivery to the inner ear
Scientific Reports, 2021 The inner ear, or cochlea, is a fluid-filled organ housing the mechanosensitive hair cells. Sound stimulation is relayed to the hair cells through waves that propagate on the elastic basilar membrane.
Laura Sumner +2 more
doaj +1 more source
Microstructural interactions contribute to the hotspot in the living cochlea
Current Research in Neurobiology, 2022 The mechanism of the active cochlea relies on a complex interaction between microstructures in the organ of Corti. A significant longitudinal vibration “hotspot” was recently observed in the high-frequency region of the living gerbil cochlea between the ...
Junpei Liu +5 more
doaj +1 more source
Design of a silicon cochlea system with biologically faithful response [PDF]
, 2015 This paper presents the design and simulation results of a silicon cochlea system that has closely similar behavior as the real cochlea. A cochlea filter-bank based on the improved three-stage filter cascade structure is used to model the frequency ...
Enemali, Godwin +5 more
core +1 more source
Macrophages in Noise-Exposed Cochlea: Changes, Regulation and the Potential Role
Aging and Disease, 2020 Acoustic trauma is an important physical factor leading to cochlear damage and hearing impairments. Inflammation responds to this kind of cochlear damage stress.
Weiwei He, Jin-tao Yu, Yu Sun, W. Kong
semanticscholar +1 more source
Drug Delivery, 2021 The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when
Samuel M. Flaherty +2 more
doaj +1 more source