Results 21 to 30 of about 66,419 (330)

Sensory processing at ribbon synapses in the retina and the cochlea.

open access: yesPhysiological Reviews, 2019
In recent years, sensory neuroscientists have made major efforts to dissect the structure and function of ribbon synapses which process sensory information in the eye and ear.
T. Moser, C. Grabner, F. Schmitz
semanticscholar   +1 more source

Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea

open access: yesFrontiers in Cellular Neuroscience, 2020
In the past, most inner ear diseases were thought to start with the impairment of the sensory epithelium of the cochlea before subsequently progressing to secondary neural degeneration.
Yutaka Koizumi   +3 more
doaj   +1 more source

Analysis of Pharmacokinetics in the Cochlea of the Inner Ear

open access: yesFrontiers in Pharmacology, 2021
Hearing loss affects >5% of the global population and therefore, has a great social and clinical impact. Sensorineural hearing loss, which can be caused by different factors, such as acoustic trauma, aging, and administration of certain classes of ...
Seishiro Sawamura   +20 more
doaj   +1 more source

Mitochondrial Damage and Necroptosis in Aging Cochlea

open access: yesInternational Journal of Molecular Sciences, 2020
Age-related hearing loss (ARHL) is an irreversible, progressive neurodegenerative disorder and is presently untreatable. Previous studies using animal models have suggested mitochondrial damage and programmed cell death to be involved with ARHL. Thus, we
Ah-Ra Lyu   +9 more
semanticscholar   +1 more source

Analysis of a Dynamic Response of the Cochlea Using Fluid-Structure Interaction Model

open access: yesEngineering Transactions, 2016
A one-dimensional (1D) model of the cochlea of the inner ear has been built and validated against the previously built three-dimensional (3D) fluid-structure interaction (FSI) model of the cochlea.
Konrad KAMIENIECKI   +2 more
doaj   +1 more source

Expression and function of scleraxis in the developing auditory system. [PDF]

open access: yesPLoS ONE, 2013
A study of genes expressed in the developing inner ear identified the bHLH transcription factor Scleraxis (Scx) in the developing cochlea. Previous work has demonstrated an essential role for Scx in the differentiation and development of tendons ...
Zoe F Mann   +4 more
doaj   +1 more source

The Role of Imaging Investigations in Evaluation of Cochlear Dimensions in Candidates for Cochlear Implantation—Our Experience

open access: yesMedicina, 2023
Background and Objectives: The Cochlear implant is the first approved cranial nerve stimulator that works by directly stimulating the cochlear nerve.
Cristian Mircea Neagoș   +3 more
doaj   +1 more source

Cisplatin is retained in the cochlea indefinitely following chemotherapy

open access: yesNature Communications, 2017
Cisplatin chemotherapy causes permanent hearing loss in 40–80% of treated patients. It is unclear whether the cochlea has unique sensitivity to cisplatin or is exposed to higher levels of the drug. Here we use inductively coupled plasma mass spectrometry
Andrew M. Breglio   +8 more
semanticscholar   +1 more source

An analog electronic cochlea [PDF]

open access: yesIEEE Transactions on Acoustics, Speech, and Signal Processing, 1988
An analog electronic cochlea has been built in CMOS VLSI technology using micropower techniques. The key point of the model and circuit is that a cascade of simple, nearly linear, second-order filter stages with controllable Q parameters suffices to capture the physics of the fluid-dynamic traveling-wave system in the cochlea, including the effects of ...
Lyon, Richard F., Mead, Carver
openaire   +5 more sources

Reconstruction of audio waveforms from spike trains of artificial cochlea models

open access: yesFrontiers in Neuroscience, 2015
Spiking cochlea models describe the analog processing and spike generation process within the biological cochlea. Reconstructing the audio input from the artificial cochlea spikes is therefore useful for understanding the fidelity of the information ...
Anja eZai   +3 more
doaj   +1 more source

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