Results 41 to 50 of about 107,745 (350)

Analysis of Pharmacokinetics in the Cochlea of the Inner Ear

Frontiers in Pharmacology, 2021
Hearing loss affects >5% of the global population and therefore, has a great social and clinical impact. Sensorineural hearing loss, which can be caused by different factors, such as acoustic trauma, aging, and administration of certain classes of ...
Seishiro Sawamura, Genki Ogata, Kai Asai, Olga Razvina, Olga Razvina, Takeru Ota, Qi Zhang, Qi Zhang, Qi Zhang, Sasya Madhurantakam, Koei Akiyama, Daisuke Ino, Sho Kanzaki, Takuro Saiki, Yoshifumi Matsumoto, Masato Moriyama, Yasuo Saijo, Arata Horii, Yasuaki Einaga, Hiroshi Hibino, Hiroshi Hibino   +20 more
doaj   +1 more source

Mitochondrial Damage and Necroptosis in Aging Cochlea

International Journal of Molecular Sciences, 2020
Age-related hearing loss (ARHL) is an irreversible, progressive neurodegenerative disorder and is presently untreatable. Previous studies using animal models have suggested mitochondrial damage and programmed cell death to be involved with ARHL. Thus, we
Ah-Ra Lyu, Tae Hwan Kim, Sung Jae Park, Sun-Ae Shin, Seong-Hun Jeong, Yang Yu, Y. Huh, A. Je, M. Park, Yong-Ho Park   +9 more
semanticscholar   +1 more source

The Evolution of Bat Vestibular Systems in the Face of Potential Antagonistic Selection Pressures for Flight and Echolocation [PDF]

, 2013
PMCID: PMC3634842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Herrel, A McVean, AJ Drummond, AJ Drummond, AZ Yang, B Turkewitsch, BP Kotler, C Dietz, CM Miller-Butterworth, D Schluter, DK Riskin, DK Riskin, DK Riskin, DR Ketten, DR Warrick, EC Teeling, EC Teeling, ER Seiffert, F Ramprashad, F Spoor, F Spoor, G Billet, G Jones, G Storch, GM Jones, GN Eick, GP Lohmann, H Nishihara, HT Arita, Ibnu Maryanto, J Gatesy, J Habersetzer, James A. Cotton, JD Hadfield, JH Ten Kate, Kalina T. J. Davies, KD Rose, KL Welker, Kornelius Kupczik, KTJ Davies, L Gustafsson, LM Witmer, M Kirkegaard, M Muller, MA Hopkins, MA Larkin, MB Fenton, MD Malinzak, MJ Benton, MS Springer, N Jeffery, N Jeffery, N Jeffery, N MacLeod, N Veselka, NB Simmons, NB Simmons, NV Jennings, P Chevret, P Gunz, Paul J. J. Bates, PD Gingerich, PG Cox, PG Cox, PW Freeman, R David, R Lebrun, RJ Knell, RW Meredith, S Ducrocq, S Nummela, SC Pedersen, SS Horowitz, Stephen J. Rossiter, T Kingston, T Kingston, T Lindenlaub, T Schmelzle, TE Macrini, UM Norberg, UM Norberg, W Graf, WE Johnson, WJ Murphy, X Zhou, Ø Hammer   +85 more
core   +7 more sources

A Case Study Assessing the Auditory and Speech Development of Four Children Implanted with Cochlear Implants by the Chronological Age of 12 Months

Case Reports in Otolaryngology, 2013
Children with severe hearing loss most likely receive the greatest benefit from a cochlear implant (CI) when implanted at less than 2 years of age. Children with a hearing loss may also benefit greater from binaural sensory stimulation. Four children who
Birgit May-Mederake, Wafaa Shehata-Dieler   +1 more
doaj   +1 more source

Reconstruction of audio waveforms from spike trains of artificial cochlea models

Frontiers in Neuroscience, 2015
Spiking cochlea models describe the analog processing and spike generation process within the biological cochlea. Reconstructing the audio input from the artificial cochlea spikes is therefore useful for understanding the fidelity of the information ...
Anja eZai, Saurabh eBhargava, Nima eMesgarani, Shih-Chii eLiu   +3 more
doaj   +1 more source

The Role of Imaging Investigations in Evaluation of Cochlear Dimensions in Candidates for Cochlear Implantation—Our Experience

Medicina, 2023
Background and Objectives: The Cochlear implant is the first approved cranial nerve stimulator that works by directly stimulating the cochlear nerve.
Cristian Mircea Neagoș, Eugenia Maria Domuța, Anca Gabriela Vlad, Adriana Neagoș   +3 more
doaj   +1 more source

Analysis of a Dynamic Response of the Cochlea Using Fluid-Structure Interaction Model

Engineering Transactions, 2016
A one-dimensional (1D) model of the cochlea of the inner ear has been built and validated against the previously built three-dimensional (3D) fluid-structure interaction (FSI) model of the cochlea.
Konrad KAMIENIECKI, Janusz PIECHNA, Paweł BORKOWSKI   +2 more
doaj   +1 more source

Insertion Guidance Based on Impedance Measurements of a Cochlear Electrode Array

Frontiers in Computational Neuroscience, 2022
The cochlear implantable neuromodulator provides substantial auditory perception to those with severe or profound impaired hearing. Correct electrode array positioning in the cochlea is one of the important factors for quality hearing, and misplacement ...
Enver Salkim, Enver Salkim, Majid Zamani, Dai Jiang, Shakeel R. Saeed, Andreas Demosthenous   +5 more
doaj   +1 more source

The Mechanism of the Cochlea [PDF]

Nature, 1922
IF I understand Dr. Perrett's letter in NATURE of November 11, p. 633, his objection to Yoshii's experiments (which would apply equally to those of Wittmaack and Siebenmann) is based on the assumption that the intensity of the stimulation of every part of the cochlea must be proportional to the amplitude of the vibration set up in that part.
openaire   +1 more source

Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea.

Comprehensive Physiology, 2017
Sound pressure fluctuations striking the ear are conveyed to the cochlea, where they vibrate the basilar membrane on which sit hair cells, the mechanoreceptors of the inner ear.
R. Fettiplace
semanticscholar   +1 more source