Results 41 to 50 of about 36,767 (171)
Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]
, 2013 Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core +1 more source
The Cochlear Tuning Curve [PDF]
, 2001 The tuning curve of the cochlea measures how large an input is required to elicit a given output level as a function of the frequency. It is a fundamental object of auditory theory, for it summarizes how to infer what a sound was on the basis of the ...
F. Rieke +6 more
core +2 more sources
Advanced Science, EarlyView.Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang +11 more
wiley +1 more source
A Gradient of Single-Channel Conductance in the Cochlea [PDF]
Neuron, 2003 AbstractFrequency tuning in the vertebrate cochlea requires a continuously varying amplifier in auditory hair cells. In this issue of Neuron, Ricci et al. show that the mechanosensitive transduction channel, a possible amplifier component, has a single-channel conductance that increases systematically along the frequency axis of the turtle cochlea.
Eunice L.M. Cheung, David P. Corey
openaire +3 more sources
Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
, 2017 open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
core +2 more sources
Advanced Science, EarlyView.AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang +8 more
wiley +1 more source
Mechanics of the Mammalian Cochlea [PDF]
Physiological Reviews, 2001 In mammals, environmental sounds stimulate the auditory receptor, the cochlea, via vibrations of the stapes, the innermost of the middle ear ossicles. These vibrations produce displacement waves that travel on the elongated and spirally wound basilar membrane (BM). As they travel, waves grow in amplitude, reaching a maximum and then dying out.
Luis Robles, Mario A. Ruggero
openaire +3 more sources
Dosimetric Analysis of Neural and Vascular Structures in Skull Base Tumors Treated with Stereotactic Radiosurgery. [PDF]
, 2017 Objective To examine the relationship between the prescribed target dose and the dose to healthy neurovascular structures in patients with vestibular schwannomas treated with stereotactic radiosurgery (SRS).
Bhatt, Jay M +6 more
core +1 more source
Advanced Science, EarlyView.In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa +6 more
wiley +1 more source
AER Auditory Filtering and CPG for Robot Control [PDF]
, 2007 Address-Event-Representation (AER) is a communication protocol for transferring asynchronous events between VLSI chips, originally developed for bio-inspired processing systems (for example, image processing).
Etienne-Cummings, R. +6 more
core +1 more source