Results 41 to 50 of about 50,225 (239)

Spiral Ganglion Cells and Macrophages Initiate Neuro-inflammation and Scarring Following Cochlear Implantation

Frontiers in Cellular Neuroscience, 2015
Conservation of a patient’s residual hearing and prevention of fibrous tissue/new bone formation around an electrode array are some of the major challenges in cochlear implant (CI) surgery.
Esperanza eBas, Stefania eGoncalves, Michelle eAdams, Christine eDinh, Jose Manuel Bas, Thomas Roger Van De Water, Adrien A Eshraghi   +6 more
doaj   +1 more source

Auditory power-law activation-avalanches exhibit a fundamental computational ground-state [PDF]

, 2016
The cochlea provides a biological information-processing paradigm that we only begin to under- stand in its full complexity. Our work reveals an interacting network of strongly nonlinear dynami- cal nodes, on which even simple sound input triggers ...
Gomez, Florian, Stoop, Ruedi
core   +1 more source

Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance

Advanced Healthcare Materials, EarlyView.
Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su, Mert Ergin, Diana Horkavcová, Victoria Horbert, Georg Matziolis, Delia S. Brauer   +5 more
wiley   +1 more source

Evolutionary origins of ultrasonic hearing and laryngeal echolocation in bats inferred from morphological analyses of the inner ear [PDF]

, 2013
PMCID: PMC3598973This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Davies, KTJ, Maryanto, I, Rossiter, SJ
core   +1 more source

Meniere's disease: Structural considerations in early cochlea hydrops

Laryngoscope Investigative Otolaryngology
Objective Structural features of the human cochlea may control early lesion formation in endolymphatic hydrops. This process may hinge on three structural features: the flattened spiral shape of the human cochlea, the toroidal configuration of the ...
Daniel J. Pender
doaj   +1 more source

Culturing Neurons on MEMS Fabricated P(VDF-TrFE) Films for Implantable Artificial Cochlea

Journal of Biomechanical Science and Engineering, 2010
In this paper, we report an in vitro study on the biocompatibility of poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) films for the implantable artificial cochlea.
Hirofumi SHINTAKU, Takashi TATENO, Nobuyoshi TSUCHIOKA, Harto TANUJAYA, Takayuki NAKAGAWA, Juichi ITO, Satoyuki KAWANO   +6 more
doaj   +1 more source

Biophysical parameters modification could overcome essential hearing gaps. [PDF]

PLoS Computational Biology, 2008
A majority of hearing defects are due to malfunction of the outer hair cells (OHCs), those cells within the mammalian hearing sensor (the cochlea) that provide an active amplification of the incoming signal.
A Kern, C Heid, W-H Steeb, N Stoop, R Stoop   +4 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Feasibility study of a hand guided robotic drill for cochleostomy [PDF]

, 2014
The concept of a hand guided robotic drill has been inspired by an automated, arm supported robotic drill recently applied in clinical practice to produce cochleostomies without penetrating the endosteum ready for inserting cochlear electrodes. The smart
Brett, P, Coulson, C, Du, X, Proops, D, Reid, A, Zoka-Assadi, M   +5 more
core   +6 more sources

Possibilities of Inner Ear Barrier Models for Otologic Drug Development

Advanced Therapeutics, EarlyView.
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn, Seonmin Choi, Minju Kim, Zachary Estlack, Daniel Brown, Jaehong Key, Young Joon Seo, Jungkyu Kim   +7 more
wiley   +1 more source