Results 61 to 70 of about 105,708 (356)

The Distribution and Prevalence of Macrophages in the Cochlea Following Cochlear Implantation in the Human: An Immunohistochemical Study Using Anti-Iba1 Antibody.

Otology and Neurotology, 2019
HYPOTHESIS Cochlear implantation may cause an increase in the number of macrophages in the human cochlea similar to previous findings in the vestibular endorgans.
T. Okayasu, A. Quesnel, J. O'malley, Takefumi Kamakura, J. Nadol   +4 more
semanticscholar   +1 more source

The Cochlea and the Carotid Canal [PDF]

Acta Radiologica, 1990
The carotid canal conveys a large artery and lies in close topographic relationship to the basal turn of the cochlea. The bony wall between them consists in some cases only of the petrous bone of the otic capsule. It can be as thin as 0.2 mm. In other cases the distance can be more than 6 mm.
H. F. Wilbrand, C. Muren, K. Wadin
openaire   +3 more sources

The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]

, 2009
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen, Fuchs, Paul A., Katz, Eleonora   +2 more
core   +1 more source

Distribution of macrophages in the developing cochlea of the common marmoset, a primate model animal

Frontiers in Immunology, 2023
IntroductionMacrophages are essential immune cells in the cochlea that contribute to inflammation, tissue repair, and homeostasis. They also play an important role in local cochlear immunity. The developmental immigration and maturation of macrophages in
Makoto Hosoya, Tsubasa Kitama, Marie N. Shimanuki, Takanori Nishiyama, Naoki Oishi, Hideyuki Okano, Hideyuki Okano, Hiroyuki Ozawa   +7 more
doaj   +1 more source

Organ of Corti vibration within the intact gerbil cochlea measured by volumetric optical coherence tomography and vibrometry.

Journal of Neurophysiology, 2018
There is indirect evidence that the mammalian cochlea in the low-frequency apical and the more commonly studied high-frequency basal regions function in fundamentally different ways.
W. Dong, A. Xia, Patrick D. Raphael, S. Puria, B. Applegate, J. Oghalai   +5 more
semanticscholar   +1 more source

Spiral Ganglion Cells and Macrophages Initiate Neuro-inflammation and Scarring Following Cochlear Implantation

Frontiers in Cellular Neuroscience, 2015
Conservation of a patient’s residual hearing and prevention of fibrous tissue/new bone formation around an electrode array are some of the major challenges in cochlear implant (CI) surgery.
Esperanza eBas, Stefania eGoncalves, Michelle eAdams, Christine eDinh, Jose Manuel Bas, Thomas Roger Van De Water, Adrien A Eshraghi   +6 more
doaj   +1 more source

Relationship of glucocorticoid receptor expression in peripheral blood mononuclear cells and the cochlea of guinea pigs and effects of dexamethasone administration. [PDF]

PLoS ONE, 2013
BACKGROUND: Glucocorticoids (GCs) are widely used to treat sudden sensorineural hearing loss (SSNHL) and significantly improve hearing. However, GC insensitivity has been observed in some patients of SSNHL.
Ling Lu, Yanhong Dai, Xiaoping Du, Wandong She, Xiuling Zhang, Qin Wu, Wenjie Yuan, Feng Chen   +7 more
doaj   +1 more source

A ratchet mechanism for amplification in low-frequency mammalian hearing

, 2010
The sensitivity and frequency selectivity of hearing result from tuned amplification by an active process in the mechanoreceptive hair cells. In most vertebrates the active process stems from the active motility of hair bundles.
A. J. Hudspeth, Ashmore, Chan, Cooper, Cooper, Dallos, Dong, Evans, Gummer, Housley, Kennedy, Khanna, Kiang, Mammano, Martin, Mellado Lagarde, Naidu, Nuttall, Robles, Ruggero, Santos-Sacchi, Sziklai, T. Reichenbach, Ulfendahl, Zheng, Zinn, Zwislocki   +26 more
core   +2 more sources

Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity [PDF]

, 2017
Cisplatin-induced ototoxicity is one of the major factors limiting cisplatin chemotherapy. Ototoxicity results from damage to outer hair cells (OHCs) and other regions of the cochlea.
Bhatta, Puspanjali, Borse, Vikrant, Dhukhwa, Asmita, FH Al Aameri, Raheem, Ghosh, Sumana, Kaur, Tejbeer, Lowy, Michelle, Mukherjea, Debashree, Ramkumar, Vickram, Rybak, Leonard P, Sheehan, Kelly, Sheth, Sandeep, Tupal, Srinivasan   +12 more
core   +2 more sources

Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea

Development, 2018
Lack of sensory hair cell (HC) regeneration in mammalian adults is a major contributor to hearing loss. In contrast, the neonatal mouse cochlea retains a transient capacity for regeneration, and forced Wnt activation in neonatal stages promotes ...
A. Samarajeewa, Danielle R. Lenz, Lihong Xie, Chiang Hao, Rory D. Kirchner, J. Mulvaney, A. Edge, A. Dabdoub   +7 more
semanticscholar   +1 more source