Results 81 to 90 of about 43,390 (337)

Complications of cochlear implantation surgery in Zagazig University Hospitals

The Egyptian Journal of Otolaryngology, 2021
Background Cochlear implantation (CI) has been established worldwide as the surgical treatment for individuals with bilateral severe to profound hearing loss.
Alaa Eldin M. Elfeky, Adly A. Tantawy, Asmaa M. Ibrahim, Ibrahim M. Saber, Said Abdel-Monem   +4 more
doaj   +1 more source

The Therapeutic Dilemma of Cochlear Nerve Deficiency: Cochlear or Brainstem Implantation?

Otolaryngology–Head and Neck Surgery, 2014
ObjectiveTo compare the outcomes between 2 age‐matched cohorts of children with cochlear nerve deficiency: those receiving auditory brainstem implants (group A) or cochlear implants (group B).Study DesignRetrospective cohort study.SettingTertiary referral center.Subjects and MethodsSubjects were selected from a pool of 537 children fitted with cochlear
L. Colletti, G. Colletti, M. Mandalà, V. Colletti   +3 more
openaire   +5 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Electrically evoked auditory brainstem response in cochlear implantation: what you need to know (short review)

The Egyptian Journal of Otolaryngology, 2022
Background Electrically evoked auditory brainstem response (E-ABR) is an evoked potential recorded from the auditory nerve in response to electric stimulation. It is considered a short latency evoked potential. It plays a vital role, especially after the
Nashwa Nada, Enaas Kolkaila, Philipp Schendzielorz, Trandil El Mahallawi   +3 more
doaj   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura, Chicca, Milvia, DANTI, SERENA, Franceschini, Valeria, Martini, Alessandro, Simoni, Edi, Valente, Filippo   +6 more
core   +2 more sources

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic cultures. [PDF]

PLoS ONE, 2013
Mefloquine is widely used for the treatment of malaria. However, this drug is known to induce neurological side effects including depression, anxiety, balance disorder, and sensorineural hearing loss.
Dalian Ding, Weidong Qi, Dongzhen Yu, Haiyan Jiang, Chul Han, Mi-Jung Kim, Kana Katsuno, Yun Hua Hsieh, Takuya Miyakawa, Richard Salvi, Masaru Tanokura, Shinichi Someya   +11 more
doaj   +1 more source

Dosimetric Analysis of Neural and Vascular Structures in Skull Base Tumors Treated with Stereotactic Radiosurgery. [PDF]

, 2017
Objective To examine the relationship between the prescribed target dose and the dose to healthy neurovascular structures in patients with vestibular schwannomas treated with stereotactic radiosurgery (SRS).
Bhatt, Jay M, Chenery, Stafford, Djalilian, Hamid R, Ghavami, Yaser, Haidar, Yarah M, Moshtaghi, Omid, Schwer, Amanda   +6 more
core   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Cochlear Implantation in Patient with Cochlear Nerve Deficiency: A Case Report

The Journal of International Advanced Otology, 2016
Diagnostic imaging methods are very important for patients with bilateral sensourinoural hearing loss. Magnetic resonance imaging (MRI) is able to demonstrate the vestibulocochlear nerve and facial nerve in the internal acoustic canal. Also computed tomography can be helpful to determination of the deficiency of the cochlear nerve.
Sürmelioğlu Ö., Tarkan Ö., Özdemir S., Tuncer Ü., Kıroğlu M., Atik F.A.   +5 more
openaire   +3 more sources