Results 131 to 140 of about 23,789 (261)
Crystals, 2018 The synthesis and single crystal structure of a new cocrystal, which is composed of OHphenolic∙∙∙OHphenolic∙∙∙Naminalic supramolecular heterosynthons assembled from 4-tert-butylphenol and the macrocyclic aminal TATU, is presented.
Augusto Rivera +3 more
doaj +1 more source
Solvates, salts, and cocrystals : a proposal for a feasible classification system [PDF]
, 2016 The design of pharmaceutical cocrystals has initiated widespread debate on the classification of cocrystals. Current attempts to classify multicomponent crystals suffer from ambiguity, which has led to inconsistent definitions for cocrystals and for ...
De Gelder, R. +4 more
core +2 more sources
Studies on Cocrystal Formation of Metaxalone with Short-chain Dicarboxylic Acids [PDF]
, 2014 Hong-Liang Lin +3 more
openalex +1 more source
PharmaceuticsReflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam +6 more
doaj +1 more source
4-Acetylpyridine–fumaric acid (2/1)
Acta Crystallographica Section E, 2009 In the crystal structure of the title cocrystal, 2C7H7NO·C4H4O4, the complete fumaric acid molecule is generated by a crystallographic inversion centre. The two components of the cocrystal are linked by an O—H...N hydrogen bond.
Kan Xu +3 more
doaj +1 more source
Vibrational assignments of two polymorphic forms of metaxolone by using DFT calculations and the SQM methodology [PDF]
, 2018 A theoretical study has been performed on the musclerelaxant 5-[(3, 5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one, of generic name metaxolone (MTX), by using the hybridB3LYP/6-31G calculations in the gas phase and theexperimental available infrared and ...
Brandan, Silvia Antonia +3 more
core
Ionic Cocrystals of Etiracetam and Levetiracetam: The Importance of Chirality for Ionic Cocrystals
Crystal Growth & Design, 2019 A striking variety of anhydrous and hydrated ionic cocrystals (ICCs) of the enantiopure antiepileptic drug (AED) levetiracetam and of its racemic intermediate etiracetam with the pharmaceutically acceptable salts CaCl2 and MgCl2 was synthesized and structurally characterized.
Lixing Song +5 more
openaire +3 more sources
Apremilast Cocrystals with Phenolic Coformers
MoleculesApremilast (APR) is an anti-inflammatory drug commonly used in the treatment of psoriasis. In efforts to enhance its solubility, several cocrystals with similar structural features have been developed. This study investigates the cocrystallization of APR with four phenolic-type coformers: phenol, catechol, pyrogallol, and hydroxyquinol. These coformers
Yelizaveta Naumkina +3 more
openaire +3 more sources
Silybin Cocrystals with Improved Solubility and Bioavailability
PharmaceuticalsBackgroud/Objectives: Silymarin, an extract from milk thistle, is widely recognized for its therapeutic potential in treating liver disorders. However, its clinical utility is limited by the poor solubility and low bioavailability of its key active ...
Bingqing Zhu +4 more
doaj +1 more source
Diels−Alder Topochemistry via Charge-Transfer Crystals: Novel (Thermal) Single-Crystal-to-Single-Crystal Transformations [PDF]
, 2001 The solid-state [4+2] cycloaddition of anthracene to bis(N-ethylimino)-1,4-dithiin occurs via a unique single-phase topochemical reaction in the intermolecular (1:1) charge-transfer crystal.
Hubig, S. M. +3 more
core +1 more source