Results 151 to 160 of about 8,500 (189)
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Chemistry – A European Journal, 2023
AbstractOrganic spintronics has caused a huge revolution in creating highly efficient low‐power circuits. Spin manipulation in organic cocrystals has become a promising strategy to uncover more chemicophysical properties for diverse applications. In this Minireview, we summarize the recent advancements of spin properties in organic charge‐transfer ...
Cheng Zhang +4 more
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AbstractOrganic spintronics has caused a huge revolution in creating highly efficient low‐power circuits. Spin manipulation in organic cocrystals has become a promising strategy to uncover more chemicophysical properties for diverse applications. In this Minireview, we summarize the recent advancements of spin properties in organic charge‐transfer ...
Cheng Zhang +4 more
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Pharmaceutical cocrystals: An overview
International Journal of Pharmaceutics, 2011Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved physicochemical properties, which has attracted increased interests from both industrial and academic researchers. In this paper a brief and systematic overview of pharmaceutical cocrystals is provided, with particular focus on cocrystal design strategies, formation ...
Qiao, N. +5 more
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Color-Tunable Upconversion-Emission Switch Based on Cocrystal-to-Cocrystal Transformation
Journal of the American Chemical Society, 2023Cocrystal engineering, involving the assembly of two or more components into a highly ordered solid-state superstructure, has emerged as a popular strategy for tuning the photophysical properties of crystalline materials. The reversible co-assembly and disassembly of multicomponent cocrystals and their reciprocal transformation in the solid state ...
Yu Wang +6 more
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Nutraceutical cocrystals: utilizing pterostilbene as a cocrystal former
CrystEngComm, 2010The nutraceutical compound pterostilbene is investigated for its propensity to form cocrystalline materials with active pharmaceutical ingredients. Three cocrystals of a 1 : 1 stoichiometric molar ratio of pterostilbene with caffeine (two polymorphs, Form I and Form II) and carbamazepine were prepared and characterized by crystallographic (XRPD, single-
Nate Schultheiss +2 more
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Development and Evolution of Energetic Cocrystals
Accounts of Chemical Research, 2021In spite of the importance of energetic materials to a broad range of military (munitions, missiles) and civilian (mining, space exploration) technologies, the introduction of new chemical entities in the field occurs at a very slow pace. This situation is understandable considering the stringent requirements for cost and safety that must be met for ...
Jonathan C. Bennion, Adam J. Matzger
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Chem. Commun., 2006
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
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The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
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Stability screening of pharmaceutical cocrystals
Pharmaceutical Development and Technology, 2021An efficient protocol for assessing both the chemical and physical stability of cocrystalline forms of active pharmaceutical ingredients (APIs) is proposed. In this protocol, the cocrystalline material is used to prepare two standard formulations, mimicking wet granulations, to make low-dose tablets.
Kenneth C, Waterman +5 more
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International Journal of Pharmaceutics, 2012
Cocrystals (CCs) used in the pharmaceutical industry are defined as complex crystals formed by reaction between an API and a cocrystal former (CCF); unlike salts, CCs do not show proton transfer. Recently, pharmaceutical CCs have been used to improve the drug-likeness of APIs, such as solubility and stability.
Katsuhiko, Yamamoto +2 more
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Cocrystals (CCs) used in the pharmaceutical industry are defined as complex crystals formed by reaction between an API and a cocrystal former (CCF); unlike salts, CCs do not show proton transfer. Recently, pharmaceutical CCs have been used to improve the drug-likeness of APIs, such as solubility and stability.
Katsuhiko, Yamamoto +2 more
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Three cocrystals and a cocrystal salt of pyrimidin-2-amine and glutaric acid
Acta Crystallographica Section C Structural Chemistry, 2015Four new cocrystals of pyrimidin-2-amine and propane-1,3-dicarboxylic (glutaric) acid were crystallized from three different solvents (acetonitrile, methanol and a 50:50 wt% mixture of methanol and chloroform) and their crystal structures determined. Two of the cocrystals, namely pyrimidin-2-amine–glutaric acid (1/1), C4H5N3·C6H8O4, (I) and (II), are ...
Isaac, Odiase +5 more
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Polymorphs and Polymorphic Cocrystals of Temozolomide
Chemistry – An Asian Journal, 2008AbstractCrystal polymorphism in the antitumor drug temozolomide (TMZ), cocrystals of TMZ with 4,4′‐bipyridine‐N,N′‐dioxide (BPNO), and solid‐state stability were studied. Apart from a known X‐ray crystal structure of TMZ (form 1), two new crystalline modifications, forms 2 and 3, were obtained during attempted cocrystallization with carbamazepine and 3‐
N Jagadeesh, Babu +3 more
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