Results 1 to 10 of about 148,988 (166)
Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness [PDF]
Background/Objectives: In the past, many drug release models have been presented which attempt to describe the interaction of drugs and excipients in a formulation.
Amelie Marie Mattusch +3 more
doaj +2 more sources
Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal [PDF]
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam +6 more
doaj +2 more sources
Impact of Tablet Shape on Drug Dissolution Rate Through Immediate Released Tablets [PDF]
Purpose: The aim of this study was to evaluate the influence of the geometric shape on the dissolution rate of the domperidone, a drug model for immediate release dosage form.
Fatima Molavi +2 more
doaj +2 more sources
The Liaoshan tunnel is one of the controlling projects of the E-han expressway, the karst geological conditions in the tunnel site area are complex. In order to deeply study the characteristics of carbonate dissolution in the field, this paper takes the ...
Huaming LI +4 more
doaj +1 more source
Cocrystallization is an emerging approach for improving physico-chemical characteristics of an active pharmaceutical ingredient (API) for instance dissolution rate, solubility, stability in addition to mechanical properties without affecting their ...
Ameera A Radhi +3 more
doaj +1 more source
Enhance dissolution rate and solubility of solid drugs through pharmaceutical deep eutectic solvents
Pharmaceutical active ingredients are usually sold in the markets in the form of solid drugs. These drugs are often associated with some problems like polymorphism, bioavailability and low solubility.
Idrees Bakr Qader
doaj +1 more source
The purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US
Mohammad Sofiqur Rahman +5 more
doaj +1 more source
The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine.
Alexandra Teleki +2 more
doaj +1 more source
INTERACTION OF 1,4-BENZODIAZEPINES WITH CERTAIN MACROMOLECULES: I- EFFECT OF NON-IONIC SURFACTANTS ON THE DISSOLUTION RATE OF TEMAZEPAM [PDF]
A recycling and automatic recording system was adopted for studying the dissolution of Temazepam via dispersed particulate and intrinsic dissolution methods. The study involves the effect of concentrations below and above CMC of polysorbates and Myris on
S. Ahmed +3 more
doaj +1 more source
Taking into account the current Product specification file, the aim of the work was to develop the composition and technology for obtaining effervescent tablets based on solid dispersions of furazolidone in the form of an aqueous solution for external ...
A. O. Elagina +10 more
doaj +1 more source

