Results 1 to 10 of about 148,988 (166)

Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness [PDF]

open access: yesPharmaceutics
Background/Objectives: In the past, many drug release models have been presented which attempt to describe the interaction of drugs and excipients in a formulation.
Amelie Marie Mattusch   +3 more
doaj   +2 more sources

Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal [PDF]

open access: yesPharmaceutics
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam   +6 more
doaj   +2 more sources

Impact of Tablet Shape on Drug Dissolution Rate Through Immediate Released Tablets [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2020
Purpose: The aim of this study was to evaluate the influence of the geometric shape on the dissolution rate of the domperidone, a drug model for immediate release dosage form.
Fatima Molavi   +2 more
doaj   +2 more sources

Experimental analysis on dissolution characteristics of carbonate rocks in Liaoshan tunnel of Emei−Hanyuan expressway in Sichuan Province

open access: yesZhongguo dizhi zaihai yu fangzhi xuebao, 2021
The Liaoshan tunnel is one of the controlling projects of the E-han expressway, the karst geological conditions in the tunnel site area are complex. In order to deeply study the characteristics of carbonate dissolution in the field, this paper takes the ...
Huaming LI   +4 more
doaj   +1 more source

Pharmaceutical cocrystal and their role in improving solid state properties of active pharmaceutical ingredients

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Cocrystallization is an emerging approach for improving physico-chemical characteristics of an active pharmaceutical ingredient (API) for instance dissolution rate, solubility, stability in addition to mechanical properties without affecting their ...
Ameera A Radhi   +3 more
doaj   +1 more source

Enhance dissolution rate and solubility of solid drugs through pharmaceutical deep eutectic solvents

open access: yesZanco Journal of Pure and Applied Sciences, 2021
Pharmaceutical active ingredients are usually sold in the markets in the form of solid drugs. These drugs are often associated with some problems like polymorphism, bioavailability and low solubility.
Idrees Bakr Qader
doaj   +1 more source

Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis

open access: yesScientific Reports, 2021
The purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US
Mohammad Sofiqur Rahman   +5 more
doaj   +1 more source

Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media

open access: yesPharmaceutics, 2020
The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine.
Alexandra Teleki   +2 more
doaj   +1 more source

INTERACTION OF 1,4-BENZODIAZEPINES WITH CERTAIN MACROMOLECULES: I- EFFECT OF NON-IONIC SURFACTANTS ON THE DISSOLUTION RATE OF TEMAZEPAM [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1985
A recycling and automatic recording system was adopted for studying the dissolution of Temazepam via dispersed particulate and intrinsic dissolution methods. The study involves the effect of concentrations below and above CMC of polysorbates and Myris on
S. Ahmed   +3 more
doaj   +1 more source

DEVELOPMENT OF NITROFURAN DERIVATIVE: COMPOSITION AND TECHNOLOGY OF EFFERVESCENT TABLETS WITH SOLID DISPERSIONS

open access: yesФармация и фармакология (Пятигорск), 2022
Taking into account the current Product specification file, the aim of the work was to develop the composition and technology for obtaining effervescent tablets based on solid dispersions of furazolidone in the form of an aqueous solution for external ...
A. O. Elagina   +10 more
doaj   +1 more source

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