Results 31 to 40 of about 5,768,654 (309)

Dual-barrel conductance micropipet as a new approach to the study of ionic crystal dissolution kinetics [PDF]

open access: yes, 2013
A new approach to the study of ionic crystal dissolution kinetics is described, based on the use of a dual-barrel theta conductance micropipet. The solution in the pipet is undersaturated with respect to the crystal of interest, and when the meniscus at ...
Massimo Peruffo   +11 more
core   +1 more source

Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

open access: yesPharmaceutics, 2021
The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej   +8 more
doaj   +1 more source

Triboelectrification and dissolution property enhancements of solid dispersions [PDF]

open access: yes, 2015
The use of solid dispersion techniques to modify physicochemical properties and improve solubility and dissolution rate may result in alteration to electrostatic properties of particles.
Conway, Barbara R   +13 more
core   +1 more source

Dissolution Profile of Nimesulide from Pharmaceutical Preparations for Oral Use

open access: yesActa Chimica Slovenica, 2016
Nimesulide belongs to the group of semi-selective COX-2 inhibitors, widely used in solid oral formulations. In the present work the influence of surfactants among other drug excipients, as well as particle size of the active substance and the effects of ...
Biljana Tubić   +3 more
doaj   +1 more source

Dissolution Kinetics of Meloxicam Formulations Co-Milled with Sodium Lauryl Sulfate

open access: yesPharmaceutics, 2022
Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required.
Jan Patera   +2 more
doaj   +1 more source

Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

open access: yes, 2023
The objective of this study was to investigate the implications of changing dissolution parameters, including pH ramp time, absence and presence of simulated intestinal fluid (SIF), and the addition of a partitioning phase, using an automated dissolution-
Anette Müllertz   +9 more
core   +1 more source

Surface‐Volume Scaling Controlled by Dissolution Regimes in a Multiphase Flow Environment

open access: yesGeophysical Research Letters, 2023
Fluid‐rock dissolution occurs ubiquitously in geological systems. Surface‐volume scaling is central to predicting overall dissolution rate R involved in modeling dissolution processes.
Chen‐Xing Zhou   +5 more
doaj   +1 more source

Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions [PDF]

open access: yes, 2008
Dissolution studies have become matter of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process.
Noelia L. Gonzalez Vidal   +8 more
core   +1 more source

Rate controls on silicate dissolution in cementitious environments

open access: yesRILEM Technical Letters, 2017
The dissolution rate of silicate minerals and glasses in alkaline environments is of importance in cementitious systems due to its influences on: (a) early-age reactivity that affects the rate of strength gain and microstructure formation, and/or, (b ...
Tandre Oey   +6 more
doaj   +1 more source

The Alkaline Dissolution Rate of Calcite [PDF]

open access: yesThe Journal of Physical Chemistry Letters, 2016
Due to the widespread presence of calcium carbonate on Earth, several geochemical systems, among which is the global CO2 cycle, are controlled to a large extent by the dissolution and precipitation of this mineral. For this reason, the dissolution of calcite has been thoroughly investigated for decades. Despite this intense activity, a consensual value
openaire   +2 more sources

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