Dual-barrel conductance micropipet as a new approach to the study of ionic crystal dissolution kinetics [PDF]
A new approach to the study of ionic crystal dissolution kinetics is described, based on the use of a dual-barrel theta conductance micropipet. The solution in the pipet is undersaturated with respect to the crystal of interest, and when the meniscus at ...
Massimo Peruffo +11 more
core +1 more source
Dissolution Profile of Nimesulide from Pharmaceutical Preparations for Oral Use
Nimesulide belongs to the group of semi-selective COX-2 inhibitors, widely used in solid oral formulations. In the present work the influence of surfactants among other drug excipients, as well as particle size of the active substance and the effects of ...
Biljana Tubić +3 more
doaj +1 more source
Dissolution Kinetics of Meloxicam Formulations Co-Milled with Sodium Lauryl Sulfate
Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required.
Jan Patera +2 more
doaj +1 more source
Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]
Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core +1 more source
Surface‐Volume Scaling Controlled by Dissolution Regimes in a Multiphase Flow Environment
Fluid‐rock dissolution occurs ubiquitously in geological systems. Surface‐volume scaling is central to predicting overall dissolution rate R involved in modeling dissolution processes.
Chen‐Xing Zhou +5 more
doaj +1 more source
Experimental determination of plagioclase dissolution rates as a function of its composition and pH at 22°C. [PDF]
The steady-state, far-from-equilibrium dissolution rates of nine distinct plagioclases ranging in composition from An2 to An89 were measured in mixed flow reactors at 22 ± 2 C and pH from 2 to 11.
Gudbrandsson S., Wolff-Boenisch D., Gislason S. R. and Oelkers E. H.
core +1 more source
Rate controls on silicate dissolution in cementitious environments
The dissolution rate of silicate minerals and glasses in alkaline environments is of importance in cementitious systems due to its influences on: (a) early-age reactivity that affects the rate of strength gain and microstructure formation, and/or, (b ...
Tandre Oey +6 more
doaj +1 more source
The Alkaline Dissolution Rate of Calcite [PDF]
Due to the widespread presence of calcium carbonate on Earth, several geochemical systems, among which is the global CO2 cycle, are controlled to a large extent by the dissolution and precipitation of this mineral. For this reason, the dissolution of calcite has been thoroughly investigated for decades. Despite this intense activity, a consensual value
openaire +2 more sources
Sensitivity of dissolution rate to location in the paddle dissolution apparatus
Abstract The aim of the present study was to determine the apparent diffusion boundary layer and dissolution rate constant for various surfaces of compacts and at various locations in the USP paddle dissolution apparatus. Benzoic acid compacts were coated with paraffin wax leaving only the surface under investigation free for dissolution.
A M, Healy +3 more
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Dissolution rate and recrystallization of sodium-molybdenum-phosphorus oxide glasses [PDF]
Phosphate glasses have been able to establish themselves and have received renewed interest from several research teams around the world. The interest shown in our laboratory contributes to the valorisation of Moroccan phosphates and brings added value ...
Abbas Lahbib +3 more
doaj +1 more source

