Results 21 to 30 of about 5,482,491 (310)
Pharmaceutics, 2021 The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej +8 more
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Triboelectrification and dissolution property enhancements of solid dispersions [PDF]
, 2015 The use of solid dispersion techniques to modify physicochemical properties and improve solubility and dissolution rate may result in alteration to electrostatic properties of particles.
Conway, Barbara R +12 more
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Dissolution Kinetics of Meloxicam Formulations Co-Milled with Sodium Lauryl Sulfate
Pharmaceutics, 2022 Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required.
Jan Patera +2 more
doaj +1 more source
Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]
, 2008 Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core +1 more source
Experimental determination of plagioclase dissolution rates as a function of its composition and pH at 22°C. [PDF]
, 2014 The steady-state, far-from-equilibrium dissolution rates of nine distinct plagioclases ranging in composition from An2 to An89 were measured in mixed flow reactors at 22 ± 2 C and pH from 2 to 11.
Gudbrandsson S., Wolff-Boenisch D., Gislason S. R. and Oelkers E. H.
core +1 more source
Surface‐Volume Scaling Controlled by Dissolution Regimes in a Multiphase Flow Environment
Geophysical Research Letters, 2023 Fluid‐rock dissolution occurs ubiquitously in geological systems. Surface‐volume scaling is central to predicting overall dissolution rate R involved in modeling dissolution processes.
Chen‐Xing Zhou +5 more
doaj +1 more source
Rate controls on silicate dissolution in cementitious environments
RILEM Technical Letters, 2017 The dissolution rate of silicate minerals and glasses in alkaline environments is of importance in cementitious systems due to its influences on: (a) early-age reactivity that affects the rate of strength gain and microstructure formation, and/or, (b ...
Tandre Oey +6 more
doaj +1 more source
The Alkaline Dissolution Rate of Calcite [PDF]
The Journal of Physical Chemistry Letters, 2016 Due to the widespread presence of calcium carbonate on Earth, several geochemical systems, among which is the global CO2 cycle, are controlled to a large extent by the dissolution and precipitation of this mineral. For this reason, the dissolution of calcite has been thoroughly investigated for decades. Despite this intense activity, a consensual value
openaire +2 more sources
Dissolution rate and recrystallization of sodium-molybdenum-phosphorus oxide glasses [PDF]
E3S Web of ConferencesPhosphate glasses have been able to establish themselves and have received renewed interest from several research teams around the world. The interest shown in our laboratory contributes to the valorisation of Moroccan phosphates and brings added value ...
Abbas Lahbib +3 more
doaj +1 more source
Sensitivity of dissolution rate to location in the paddle dissolution apparatus
Journal of Pharmacy and Pharmacology, 2002 Abstract The aim of the present study was to determine the apparent diffusion boundary layer and dissolution rate constant for various surfaces of compacts and at various locations in the USP paddle dissolution apparatus. Benzoic acid compacts were coated with paraffin wax leaving only the surface under investigation free for dissolution.
A M, Healy +3 more
openaire +2 more sources