Results 11 to 20 of about 177,103 (312)

Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide

open access: yesInternational Journal of Nanomedicine, 2012
Kwang-Ho Cha,1,3 Kyung-Jin Cho,3 Min-Soo Kim,4 Jeong-Soo Kim,3 Hee Jun Park,1,3 Junsung Park,1,3 Wonkyung Cho,1,3 Jeong-Sook Park,3 Sung-Joo Hwang1,21Yonsei Institute of Pharmaceutical Sciences, 2College of Pharmacy, Yonsei University, Incheon, Republic ...
Cha KH   +8 more
doaj   +1 more source

On methods of expressing dissolution rate data

open access: yesJournal of Pharmacy and Pharmacology, 1978
Abstract The value of the Weibull, logarithmic-logistic, and logarithmic-normal plots in expressing dissolution rate data is considered for the combinations of zero and first-order release with sink and non-sink conditions, and for actual dissolution rate data of diazepam from tablets in a medium of pH 2.
J A, Goldsmith, N, Randall, S D, Ross
openaire   +3 more sources

Preparation and characterization of fenofibrate-loaded zeolitic imidazolate frameworks and their evaluation in dissolution enhancement of the formulation [PDF]

open access: yesشیمی کاربردی روز, 2021
The purpose of this study was to develop zeolitic imidazolate frameworks (ZIFs) incorporated with poorly water-soluble drug fenofibrate (FEN), belonging to Biopharmaceutical Classification System (BCS) class II, to improve drug dissolution, intended to ...
Aziz maleki   +5 more
doaj   +1 more source

Preparation and Characterization of Instant Casein Phosphopeptide by Supercritical Fluid Assisted Atomization

open access: yesFoods, 2021
Casein phosphopeptide (CPP) has been widely used as micronutrient supplementation for certain populations. However, its solubility performance is far from satisfying.
Jian Zhu   +5 more
doaj   +1 more source

Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods

open access: yesPharmaceutics, 2019
The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray ...
Tereza Školáková   +5 more
doaj   +1 more source

ENHANCEMENT OF DISSOLUTION AND THE ANTIINFLAMMATORY EFFECT OF NIMESULIDE, USING LIQUISOLID COMPACT FOR ORAL APPLICATION [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2011
Nimesulide is a poorly soluble drug, the rate of its oral absorption is often controlled bythe dissolution rate in the gastrointestinal tract. There are several techniques to enhance thedissolution of poorly soluble drugs.
H. El-Saghir, M. Hassan
doaj   +1 more source

Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine) [PDF]

open access: yes, 2007
Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica.
Yousef Javadzadeh   +8 more
core   +1 more source

Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification [PDF]

open access: yes, 2017
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance is highly or poorly soluble.
Raimar Löbenberg   +13 more
core   +1 more source

Moving and Union Dissolution [PDF]

open access: yes, 2008
This paper examines the effect of migration and residential mobility on union dissolution among married and cohabiting couples. Moving is a stressful life event, and a large, multidisciplinary litera-ture has shown that family migration often benefits ...
Cooke, T.   +11 more
core   +1 more source

Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

open access: yesPharmaceutics, 2021
The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej   +8 more
doaj   +1 more source

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