The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray ...
Tereza Školáková +5 more
doaj +1 more source
Preparation and characterization of fenofibrate-loaded zeolitic imidazolate frameworks and their evaluation in dissolution enhancement of the formulation [PDF]
The purpose of this study was to develop zeolitic imidazolate frameworks (ZIFs) incorporated with poorly water-soluble drug fenofibrate (FEN), belonging to Biopharmaceutical Classification System (BCS) class II, to improve drug dissolution, intended to ...
Aziz maleki +5 more
doaj +1 more source
Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine) [PDF]
Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica.
Yousef Javadzadeh +8 more
core +1 more source
ENHANCEMENT OF DISSOLUTION AND THE ANTIINFLAMMATORY EFFECT OF NIMESULIDE, USING LIQUISOLID COMPACT FOR ORAL APPLICATION [PDF]
Nimesulide is a poorly soluble drug, the rate of its oral absorption is often controlled bythe dissolution rate in the gastrointestinal tract. There are several techniques to enhance thedissolution of poorly soluble drugs.
H. El-Saghir, M. Hassan
doaj +1 more source
Casein phosphopeptide (CPP) has been widely used as micronutrient supplementation for certain populations. However, its solubility performance is far from satisfying.
Jian Zhu +5 more
doaj +1 more source
Development and assessment of a USP Apparatus 3 dissolution test method for sustained-release Nevirapine matrix tablets [PDF]
Dissolution testing is a quality control tool used to assess batch-to-batch performance of dosage forms, thereby providing continued assurance of product quality.
Mwila, Chiluba +2 more
core +1 more source
Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification [PDF]
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance is highly or poorly soluble.
Raimar Löbenberg +13 more
core +1 more source
Moving and Union Dissolution [PDF]
This paper examines the effect of migration and residential mobility on union dissolution among married and cohabiting couples. Moving is a stressful life event, and a large, multidisciplinary litera-ture has shown that family migration often benefits ...
Cooke, T. +11 more
core +2 more sources
Dual-barrel conductance micropipet as a new approach to the study of ionic crystal dissolution kinetics [PDF]
A new approach to the study of ionic crystal dissolution kinetics is described, based on the use of a dual-barrel theta conductance micropipet. The solution in the pipet is undersaturated with respect to the crystal of interest, and when the meniscus at ...
Massimo Peruffo +11 more
core +1 more source
Dissolution Profile of Nimesulide from Pharmaceutical Preparations for Oral Use
Nimesulide belongs to the group of semi-selective COX-2 inhibitors, widely used in solid oral formulations. In the present work the influence of surfactants among other drug excipients, as well as particle size of the active substance and the effects of ...
Biljana Tubić +3 more
doaj +1 more source

