Results 11 to 20 of about 149,798 (265)
Preparation and characterization of fenofibrate-loaded zeolitic imidazolate frameworks and their evaluation in dissolution enhancement of the formulation [PDF]
شیمی کاربردی روز, 2021 The purpose of this study was to develop zeolitic imidazolate frameworks (ZIFs) incorporated with poorly water-soluble drug fenofibrate (FEN), belonging to Biopharmaceutical Classification System (BCS) class II, to improve drug dissolution, intended to ...
Aziz maleki +5 more
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Foods, 2021 Casein phosphopeptide (CPP) has been widely used as micronutrient supplementation for certain populations. However, its solubility performance is far from satisfying.
Jian Zhu +5 more
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Pharmaceutics, 2019 The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray ...
Tereza Školáková +5 more
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ENHANCEMENT OF DISSOLUTION AND THE ANTIINFLAMMATORY EFFECT OF NIMESULIDE, USING LIQUISOLID COMPACT FOR ORAL APPLICATION [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2011 Nimesulide is a poorly soluble drug, the rate of its oral absorption is often controlled bythe dissolution rate in the gastrointestinal tract. There are several techniques to enhance thedissolution of poorly soluble drugs.
H. El-Saghir, M. Hassan
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Pharmaceutics, 2021 The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej +8 more
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Dissolution Profile of Nimesulide from Pharmaceutical Preparations for Oral Use
Acta Chimica Slovenica, 2016 Nimesulide belongs to the group of semi-selective COX-2 inhibitors, widely used in solid oral formulations. In the present work the influence of surfactants among other drug excipients, as well as particle size of the active substance and the effects of ...
Biljana Tubić +3 more
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Dissolution Kinetics of Meloxicam Formulations Co-Milled with Sodium Lauryl Sulfate
Pharmaceutics, 2022 Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required.
Jan Patera +2 more
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Surface‐Volume Scaling Controlled by Dissolution Regimes in a Multiphase Flow Environment
Geophysical Research Letters, 2023 Fluid‐rock dissolution occurs ubiquitously in geological systems. Surface‐volume scaling is central to predicting overall dissolution rate R involved in modeling dissolution processes.
Chen‐Xing Zhou +5 more
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Rate controls on silicate dissolution in cementitious environments
RILEM Technical Letters, 2017 The dissolution rate of silicate minerals and glasses in alkaline environments is of importance in cementitious systems due to its influences on: (a) early-age reactivity that affects the rate of strength gain and microstructure formation, and/or, (b ...
Tandre Oey +6 more
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The Alkaline Dissolution Rate of Calcite [PDF]
The Journal of Physical Chemistry Letters, 2016 Due to the widespread presence of calcium carbonate on Earth, several geochemical systems, among which is the global CO2 cycle, are controlled to a large extent by the dissolution and precipitation of this mineral. For this reason, the dissolution of calcite has been thoroughly investigated for decades. Despite this intense activity, a consensual value
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