Results 181 to 190 of about 16,526 (214)

Exploring cocrystal–cocrystal reactivity via liquid-assisted grinding: the assembling of racemic and dismantling of enantiomeric cocrystals

Chem. Commun., 2006
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav, Fabian, Laszlo, Burley, Jonathan C., Jones, William, Motherwell, W. D. Samuel   +4 more
openaire   +3 more sources

Achieving High-Temperature Phosphorescence by Organic Cocrystal Engineering.

Angewandte Chemie
Organic phosphors offer a promising alternative in optoelectronics, but their temperature-sensitive feature has restricted their applications in high-temperature scenarios, and the attainment of high-temperature phosphorescence (HTP) is still challenging.
Manjeet Singh, Kang Shen, Wenpeng Ye, Yanhua Gao, Anqi Lv, Kun Liu, Huili Ma, Zhengong Meng, Huifang Shi, Zhongfu An   +9 more
semanticscholar   +1 more source

Cocrystal Strategy toward Multifunctional 3D‐Printing Scaffolds Enables NIR‐Activated Photonic Osteosarcoma Hyperthermia and Enhanced Bone Defect Regeneration

Advanced Functional Materials, 2020
Malignant bone tumors are one of the major serious diseases in clinic. Inferior reconstruction of new bone and rapid propagation of residual tumor cells are the main challenges to surgical intervention.
Huijing Xiang, Qianhao Yang, Youshui Gao, Daoyu Zhu, Shanshan Pan, Tianming Xu, Yu Chen   +6 more
semanticscholar   +1 more source

In-silico methods of cocrystal screening: A review on tools for rational design of pharmaceutical cocrystals

, 2021
Pharmaceutical cocrystals represent a distinctive class of crystal engineered multicomponent systems consisting an API and a crystal former non-covalently linked together in the same crystal lattice.
Arun Kumar, A. Nanda
semanticscholar   +1 more source

Anion-Counterion Strategy toward Organic Cocrystal Engineering for Near-Infrared Photothermal Conversion and Solar-Driven Water Evaporation.

Angewandte Chemie
An anion-counterion strategy is proposed to construct organic mono-radical charge-transfer cocrystals for near-infrared photothermal conversion and solar-driven water evaporation.
Mengmeng Zhang, Shunli Chen, Anran Bao, Yanqi Chen, Hui Liang, Shaomin Ji, Jiecheng Chen, Bowei Ye, Qingwei Yang, Yuli Liu, Jiayu Li, Wenbin Chen, Xinda Huang, Shaofei Ni, Li Dang, Ming-de Li   +15 more
semanticscholar   +1 more source

Celecoxib–Nicotinamide Cocrystal Revisited: Can Entropy Control Cocrystal Formation?

Crystal Growth & Design, 2017
The cocrystal of celecoxib–nicotinamide has been revisited to reveal its crystal structure and unusual formation properties. Gibbs free energy and enthalpy of formation at 25 °C were determined by solubility and thermal analysis. The formation of celecoxib–nicotinamide was found to be an endothermic process and driven by entropy, a mechanism different ...
Si-Wei Zhang, Andrew P. J. Brunskill, Eric Schwartz, Shuwen Sun   +3 more
openaire   +1 more source

Production of curcumin-resveratrol cocrystal using cocrystallization with supercritical solvent

, 2021
Bioactive compounds curcumin and resveratrol have been appointed to have potential for prevention and treatment of several diseases, replacing synthetic compounds with limited action.
Camila Dal Magro, A. E. Santos, Marcela M. Ribas, G. P. Aguiar, Carolin R.B. Volfe, M. Lopes, A. Siebel, L. Müller, A. Bortoluzzi, M. Lanza, J. V. Oliveira   +10 more
semanticscholar   +1 more source

Deep insight into the charge transfer interactions in 1,2,4,5-tetracyanobenzene-phenazine cocrystal

, 2021
A new charge transfer cocrystal of 1,2,4,5-tetracyanobenzene (TCNB)-phenazine (PTC) was prepared by solvent evaporation method. The donor and acceptor molecules of cocrystal are stacked face to face with a mixed-stacking, implying a strong charge ...
Hong Wu, Yajing Sun, Lingjie Sun, Liwei Wang, Xiaotao Zhang, Wenping Hu   +5 more
semanticscholar   +1 more source

In Vitro-In Vivo Correlation in Cocrystal Dissolution: Consideration of Drug Release Profiles Based on Coformer Dissolution and Absorption Behavior.

Molecular Pharmaceutics, 2021
This study assessed the in vitro-in vivo correlation in cocrystal dissolution based on the coformer behavior. 4-Aminobenzoic acid (4ABA) was used as a coformer.
M. Kataoka, Keiko Minami, T. Takagi, G. Amidon, S. Yamashita   +4 more
semanticscholar   +1 more source

Pharmaceutical cocrystals: walking the talk

Chemical Communications, 2016
From Saridon to Entresto: the journey of pharmaceuticals from the first drug–drug combination of propyphenazone and pyrithyldione in 1937 (left) to the most recent monosodium sacubitril and disodium valsartan in 2015 (right).
Geetha, Bolla, Ashwini, Nangia
openaire   +2 more sources