Results 131 to 140 of about 5,297,063 (270)

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

open access: yesBMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han   +9 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Quantitative characterization of the 3D self-organization of PDAC tumor spheroids reveals cell type and matrix dependence through advanced microscopy analysis

open access: yesAPL Bioengineering
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant tumor-associated stroma composed from pancreatic stellate cells, which play a critical role in tumor progression.
Soraya Hernández-Hatibi   +5 more
doaj   +1 more source

Cellular Layer-by-Layer Coculture Platform Using Biodegradable, Nanoarchitectured Membranes for Stem Cell Therapy

open access: yes, 2017
Stem cells are regulated in vivo through interactions with the surrounding microenvironments in a three-dimensional (3D) manner. A coculture of stem cells with desired cell types, which recapitulates the complex in vivo cell cell communications, has been
Kim, Byung-Soo   +16 more
core   +1 more source

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

open access: yesBMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang   +11 more
wiley   +1 more source

30. MONTE CARLO TECHNIQUES

open access: yes, 2008
Monte Carlo techniques are often the only practical way to evaluate difficult integrals or to sample random variables governed by complicated probability density functions.
Monte Carlo Techniques
core  

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

open access: yesElectron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary   +5 more
wiley   +1 more source

Beyond Conventional PDOs: Organoids for Tumorigenesis for Gut Cancer Modeling and Fast Clinical Decision

open access: yesGut Medicine, EarlyView.
ABSTRACT Reproducing tumor biology in vivo using three‐dimensional organoids remains a debated topic in the cancer organoid field, despite the new FDA framework for evaluating cancer drugs with organoid models. Compared with patient‐derived organoids (PDOs), which offer a humanized model for testing cancer therapies, organoids derived from normal stem ...
Chong Gao
wiley   +1 more source

Sustainable Blue Foods from Rice–Animal Coculture Systems

open access: yes
Global interest grows in blue foods as part of sustainable diets, but little is known about the potential and environmental performance of blue foods from rice–animal coculture systems.
LongLong Xia (18154060)   +9 more
core   +2 more sources

To really know them you have to grow them

open access: yesBioingeniøren, 2017
Background: Only a small fraction of bacteria in complex environmental samples, such as soil, water and sediments can at present be grown on synthetic media under laboratory conditions.
Colin Charnock   +2 more
doaj  

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