Results 91 to 100 of about 25,706 (245)

Preventing another Codeine debacle? Pharmacist management of analgesia

, 2017
The announcement that OTC codeine-containing products will be up-scheduled to Prescription Only in 2018 may have come as a surprise to many pharmacists. However, rather than simply bemoaning the decision, we should look at how, as a profession, we might ...
Hall, Tony, Lau, Esther, Nissen, Lisa
core  

Codeine References in Rap Music Increase after Codeine Availability Decreases

, 2019
Increased consumption of “purple drank,” a combination of codeine cough syrup and soda, is linked to more frequent listening to rap music. In 2014, combined promethazine/codeine was pulled from the over-the-counter market.
Roberts, Emilee, Byars, Kara
core  

Pharmacists role in codeine dependence treatment [PDF]

, 2017
Kodein je najčešće korišteni opijat diljem svijeta te se u posljednjem desetljeću bilježi porast potražnje od 27%. Brojna istraživanja su ukazala na povezanost bezreceptnih kodeinskih analgetika i nuspojava te razvoja ovisnosti.
Radovanović, Tessa
core  

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

‘Codeine is my companion’: misuse and dependence on codeine containing medicines in Ireland [PDF]

Objectives: Global concern around over the counter availability of codeine containing products and risk of misuse, dependence and related harms are evident.
Santlal, K, Bergin, M, Van Hout, MC, Rich, E, Horan, A   +4 more
core   +1 more source

Inhibition of Brain CYP2D Lowers Codeine-induced Analgesia in Rats

, 2012
CYP2D6 metabolizes codeine to morphine, the active analgesic metabolite. Variation in brain CYP2D6 activity may affect brain morphine levels after codeine administration and thereby influence analgesia. We investigate the effect of inhibiting brain CYP2D
Zhou, Kaidi
core   +1 more source

Prediction of codeine toxicity in infants and their mothers using a novel combination of maternal genetic markers

, 2012
Substantial variation exists in response to standard doses of codeine ranging from poor analgesia to life-threatening central nervous system (CNS) depression.
Sistonen, J, Carleton, B C, Yazdanpanah, M, Lee, J W, Nauta, M, Hayden, M R, Madadi, P, Landsmeer, M L A, Koren, G, Ross, C J   +9 more
core   +1 more source

Antitussive codeine medicines in Ukraine: clinical and pharmacological, marketing, regulatory aspects, and forecasts

Annals of Mechnikov's Institute
Introduction. The circulation and use of codeine-containing medicines require careful regulation to ensure effective treatment of pain and cough and minimize the risks of misuse. In Ukraine, the availability of such medicines is the subject of regulatory
Oleksandr Nevzghoda, Alina Osyntseva, Valentyn Shapovalov, Viktoriia Shapovalova, Oleksandr Veits   +4 more
doaj   +1 more source

Essential medications in palliative care: an updated survey of Australian and New Zealand medical practitioners practising palliative care

Internal Medicine Journal, EarlyView.
Abstract Background Palliative care patients experience complex symptoms requiring varied pharmacological management. Medication choice depends on the underlying aetiology of symptoms, guideline recommendations, clinician preference and medication availability.
Jack Power, Tim Luckett, Richard McNeill, David Currow, Amanda Landers, Gregory B. Crawford, Slavica Kochovska, Philip Good, Jessica Boyley, Sungwon Chang, Lisa Mounsey   +10 more
wiley   +1 more source