Results 71 to 80 of about 27,730 (240)
Quantitative Measurements of Codeine and Fentanyl on a Surface-Enhanced Raman-Active Pad
Molecules, 2019 The USA is in the midst of an opioid crisis that included over 60,000 overdose fatalities in 2017, mostly unintentional. This is due to excessive use of prescription opioids and the use of very strong synthetic opioids, such as fentanyl, mixed with ...
Chetan Shende +4 more
doaj +1 more source
Gender &History, EarlyView.ABSTRACT A new archive of oral history interviews from LGBTQIA‐identified alumni, faculty and staff reveals the complex ways that queer and transgender students understood, experienced and remembered the long transition from single‐sex to coeducation at Princeton University.
Ezelle Sanford III +2 more
wiley +1 more source
BMC Veterinary Research, 2022 Background In humans, codeine is a commonly prescribed analgesic that produces its therapeutic effect largely through metabolism to morphine. In some species, analgesic effects of morphine have also been attributed to the morphine-6-glucuronide (M6G ...
Heather K. Knych +4 more
doaj +1 more source
Journal of Forensic Sciences, EarlyView.Abstract Novel psychoactive substances (NPS) are compounds emerging as alternatives to more established drugs of abuse. They are constantly changing and being modified, which makes their detection difficult. The study objective was to determine the prevalence of NPS in selected clinical specimens. Deidentified urine specimen remnants were analyzed that
Jillian R. Neifeld +2 more
wiley +1 more source
Frontiers in PharmacologyObjectivesCodeine, a prodrug used as an opioid agonist, is metabolized to the active product morphine by CYP2D6. This study aimed to establish physiologically based pharmacokinetic (PBPK) models of codeine and morphine and explore the influence of CYP2D6
Yujie Yang +5 more
doaj +1 more source
Human Resource Management Journal, EarlyView.ABSTRACT Problematic substance use (PSU) is a significant, inadequately managed people management challenge. Drawing on the conflicting outcomes and mutual losses perspectives on HRM and employee wellbeing, and using Job Demands‐Resources theory to explain underlying strain‐driven loss cycles, we examine factors shaping PSU and help‐seeking among 575 ...
Karen Maher +4 more
wiley +1 more source
Addiction, EarlyView.Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke +5 more
wiley +1 more source
CODEINE ANALGESIA IS DUE TO CODEINE‐6‐GLUCURONIDE, NOT MORPHINE
International Journal of Clinical Practice, 2000 SUMMARYEighty per cent of codeine is conjugated with glucuronic acid to codeine‐6‐glucuronide. Only 5% of the dose is O‐demethylated to morphine, which in turn is immediately glucuronidated at the 3‐ and 6‐ position and excreted renally. Based on the structural requirement of the opiate molecule for interaction with the μ‐receptor to result in ...
Vree, T.B. +2 more
openaire +3 more sources
Scientists want to figure out the best way to use codeine – without getting addicted to it.
, 2014 Researchers in Waterford Institute of Technology are trying to figure out how to get the best out of codeine – without getting addicted to it. The €2 million project, launched this week, will look into codeine use, misuse and dependence in Ireland, the ...
core
A Case of Codeine Induced Anaphylaxis via Oral Route. [PDF]
, 2014 Codeine is widely prescribed in clinical settings for the relief of pain and non-productive coughs. Common adverse drug reactions to codeine include constipation, euphoria, nausea, and drowsiness. However, there have been few reports
Shin, YS +7 more
core +1 more source