Results 71 to 80 of about 47,580 (219)

A European multicentre drug utilisation study of the impact of regulatory measures on prescribing of codeine for pain in children [PDF]

open access: yes, 2019
Purpose: In June 2013, following recommendations from the World Health Organization (WHO) and Food and Drug Administration (FDA), the European Medicines Agency agreed updates to the codeine product information regarding use for pain in children younger ...
Arlett, Peter   +10 more
core   +2 more sources

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort   +8 more
wiley   +1 more source

Pharmacokinetics, adverse effects and effects on thermal nociception following administration of three doses of codeine to horses

open access: yesBMC Veterinary Research, 2022
Background In humans, codeine is a commonly prescribed analgesic that produces its therapeutic effect largely through metabolism to morphine. In some species, analgesic effects of morphine have also been attributed to the morphine-6-glucuronide (M6G ...
Heather K. Knych   +4 more
doaj   +1 more source

Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]

open access: yes, 2011
The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena   +5 more
core   +2 more sources

Insights from a 6‐year hair drug analysis compendium in drug‐facilitated sexual assault cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated sexual assault (DFSA) may involve a diverse array of substances, including illicit drugs, prescription medications, and over‐the‐counter pharmaceuticals. Hair analysis has emerged as a valuable forensic tool, offering an extended window of detection spanning several months. However, interpreting drug concentrations in hair can
Amandine Fort   +8 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

open access: yesAnaesthesia, EarlyView.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe   +2083 more
wiley   +1 more source

Comprehensive Analysis of Detection Methods for Over-the-counter Codeine: A Systematic Review

open access: yesJournal of Forensic Science and Medicine
Concerns have been raised about how readily available over-the-counter (OTC) codeine formulations may be contributing to the expanding opioid epidemic.
Anagha Ravindran   +2 more
doaj   +1 more source

PEPFAR Public Health Evaluation-Care and Support -Phase I Kenya [PDF]

open access: yes, 2009
Phase 1, a survey of 120 care facilities in Kenya and Uganda, found that over 90% of facilities provided some level of clinical, psychological,and preventive care. Pain control was very limited with paracetamol often the only analgesic.
Eve Namisango   +9 more
core  

The clinical meaning of histamine skin reactivity [PDF]

open access: yes, 2015
The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
core   +1 more source

Laparoscopically guided transversus abdominis plane block versus local wound infiltration analgesia in laparoscopic surgery for peritoneal endometriosis: A prospective randomized controlled double‐blinded LTAP‐trial

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
No statistically significant difference in the mean or median opioid consumption between laparoscopically guided transversus abdominis plane block (LTAP) and local wound infiltration analgesia (LWI) (control) analgesia for laparoscopic peritoneal endometriosis surgery.
Anna M. Terho   +6 more
wiley   +1 more source

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