Results 71 to 80 of about 22,944 (196)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Electrochemical Detection of Codeine in Pharmaceutical Tablets Using a Tungsten Oxide Nanoparticles and Carbon Nanotubes Modified Electrode

International Journal of Electrochemical Science, 2016
An electrochemical sensor with a glassy carbon electrode (GCE) decorated with a composite of carbon nanotubes (CNTs) and tungsten oxide (WO3) was prepared for the quantification of codeine. The crystal structure of the CNT-WO3 composite was characterized
Qian Yu, Xianhui Yang, Yan Chen
doaj   +1 more source

Opioid use, disability, and patient‐reported cognitive impairment in migraine: Multi‐country results from the Chronic Migraine Epidemiology and Outcomes—International Study

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Opioids are widely used to treat migraine despite being contrary to clinical guidelines. In the Chronic Migraine Epidemiology and Outcomes–International (CaMEO‐I) Study, a large, international survey of people with migraine, opioid users were more likely than nonusers to experience moderate or severe migraine‐related disability ...
Elizabeth Leroux, Dawn C. Buse, Michel Lanteri‐Minet, Fumihiko Sakai, Manjit Matharu, Zaza Katsarava, Kristina M. Fanning, Karen Carr, Nicole Naccara, Janette Contreras‐De Lama, Richard B. Lipton   +10 more
wiley   +1 more source

Real‐world diagnosis and treatment of individuals with migraine in the United States: The Migraine Insights in Diagnosis and Treatment (MIND) study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to describe the real‐world diagnosis and treatment patterns of individuals newly diagnosed with migraine in the United States (US). Background Over 10% of adults in the US are living with migraine.
Fred Cohen, Vincent Martin, Avani Patel, Shelby L. Corman, Katie B. Tellor, Meghan Fajardo, D. Cortney Hayflinger, Simon Dagenais   +7 more
wiley   +1 more source

Postoperative Sequelae and Complications of Alveolar Ridge Augmentation With Simultaneous Implant Placement. A Retrospective Cohort‐Based Predictive Risk Modelling

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims To quantify the incidence and develop predictive models for postoperative sequelae and complications (POSC) and the need for additional grafting after alveolar ridge augmentation with simultaneous implant placement (SARA). Methods This longitudinal retrospective cohort included adults with ridge deficiencies who underwent SARA with ...
Muhammad H. A. Saleh, Hend Abulatifa, Francesco Fanelli, Abdusalam E. Alrmali, Asmaa W. Issa, Hom‐Lay Wang, Giuseppe Troiano   +6 more
wiley   +1 more source

Trends in opioid dispensing to injured workers following codeine scheduling changes in Australia: a retrospective cohort study

BMJ Open
Objectives To describe the prevalence and patterns of opioid analgesic and pain medicine dispenses, and the impact of up-scheduling of low-dose (≤15 mg) codeine-containing products to Australians with accepted workers’ compensation time loss claims for ...
Alex Collie, Christopher Maher, Ting Xia, Giovanni E Ferreira, Christina Abdel Shaheed, Stephanie Mathieson, Yonas Getaye Tefera, Michael F Di Donato   +7 more
doaj   +1 more source

Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Introduction Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep‐related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long‐term use. Despite these risks, Canada lacks standardized prescribing guidelines for older adults with
Anum Ali, Mina Tadrous, Chizaram Eje, Laleh Rashidian, Arrani Senthinathan, Cherry Chu, Kerry Kuluski, Sara J. T. Guilcher   +7 more
wiley   +1 more source

Clinical practices in the management of cervical Hansen type I intervertebral disc herniation among veterinary neurologists in North America and Europe

Journal of Small Animal Practice, EarlyView.
Objectives To describe current clinical practices in the management of cervical Hansen type I intervertebral disc herniation among American College of Veterinary Internal Medicine/European College of Veterinary Neurology neurologists. Materials and Methods An anonymous web‐based survey was distributed via professional listservs between October and ...
A. Mondino, M. Riobó, N. J. Olby, S. Moore, P. J. Early   +4 more
wiley   +1 more source

Evidence for peripheral and central actions of codeine to dysregulate swallowing in the anesthetized cat

Frontiers in Neurology
Systemic administration of opioids has been associated with aspiration and swallow dysfunction in humans. We speculated that systemic administration of codeine would induce dysfunctional swallowing and that this effect would have a peripheral component ...
Donald C. Bolser, Tabitha Y. Shen, M. Nicholas Musselwhite, Melanie J. Rose, John A. Hayes, Teresa Pitts   +5 more
doaj   +1 more source

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

Journal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen, B. D. X. Lascelles, B. P. Monteiro, J. C. Murrell, S. A. Robertson, P. V. Steagall, B. Wright   +6 more
wiley   +1 more source