Results 71 to 80 of about 1,107,083 (308)
Codon usage and the origin of P elements [PDF]
Molecular Biology and Evolution, 1996 Uploaded by Plazi for TaxoDros. We do not have abstracts.
J R, Powell, J M, Gleason
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Codon usage in twelve species of Drosophila [PDF]
BMC Evolutionary Biology, 2007 AbstractBackgroundCodon usage bias (CUB), the uneven use of synonymous codons, is a ubiquitous observation in virtually all organisms examined. The pattern of codon usage is generally similar among closely related species, but differs significantly among distantly related organisms, e.g., bacteria, yeast, andDrosophila.
Vicario S, Moriyama EN, Powell JR
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Scaled codon usage similarity index: A comprehensive resource for crop plants
Journal of Genetic Engineering and BiotechnologyOver the past three decades species-specific codon usage bias has been used to optimize heterologous gene expression in the target host. However, synthesizing codon optimized gene for multiple species is not achievable due to the prohibitive expense of ...
Taniya Bargoti +5 more
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Analysis of transcriptome data reveals multifactor constraint on codon usage in Taenia multiceps
BMC Genomics, 2017 Background Codon usage bias (CUB) is an important evolutionary feature in genomes that has been widely observed in many organisms. However, the synonymous codon usage pattern in the genome of T. multiceps remains to be clarified.
Xing Huang +6 more
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Intron Length and Codon Usage [PDF]
Journal of Molecular Evolution, 2001 The correlation was shown between the length of introns and the codon usage of the coding sequences of the corresponding genes, which in some cases can be related to the level of gene expression. The link is positive in the unicellular organisms, i.e., genes with the longer introns show the higher bias of codon usage.
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A general model of codon bias due to GC mutational bias.
PLoS ONE, 2010 BackgroundIn spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been lacking.
Gareth A Palidwor +2 more
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, 2016 Codon usage and codon—anticodon recognition pattern for tRNA in Utricularia reniformis cp genome.
Alessandro M. Varani (3233757) +7 more
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