Results 161 to 170 of about 36,066 (191)
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Synonymous codon usage bias in Oryza sativa
Plant Science, 2004By using 1860 cDNA sequences containing complete coding sequence (CDS), a detailed analysis of the effects of several factors on codon usage in rice was performed. The results showed that axis 1 coordinates were significantly positively correlated with GC3s and GC content (r=0.993 and 0.954, respectively ...
Qingpo Liu +4 more
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Codon Usage Bias and tRNA Abundance in Drosophila
Journal of Molecular Evolution, 1997Codon usage bias of 1,117 Drosophila melanogaster genes, as well as fewer D. pseudoobscura and D. virilis genes, was examined from the perspective of relative abundance of isoaccepting tRNAs and their changes during development. We found that each amino acid contributes about equally and highly significantly to overall codon usage bias, with the ...
E N, Moriyama, J R, Powell
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An Evaluation of Measures of Synonymous Codon Usage Bias
Journal of Molecular Evolution, 1998Synonymous codons are not generally used at equal frequencies, and this trend is observed for most genes and organisms. Several methods have been proposed and used to estimate the degree of the nonrandom use of the different synonymous codons. The estimates obtained by these methods, however, show different levels of both precision and dispersion when ...
J M, Comeron, M, Aguadé
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Codon usage bias in metagenomes
2008Codon usage (CU) bias is an effect predominant in prokaryotes whereby synonymous codons are used with different frequencies between different species and even between genes within a single genome. This effect is related to tRNA abundance and can be used to predict expressivity of proteins by comparing their CU with that of a reference set of ...
Vlahoviček, Kristian, Lucić, Vedran
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Nucleotide composition and codon usage bias of SRY gene
Andrologia, 2017The SRY gene is present within the sex-determining region of the Y chromosome which is responsible for maleness in mammals. The nonuniform usage of synonymous codons in the mRNA transcript for encoding a particular amino acid is the codon usage bias (CUB). Analysis of codon usage pattern is important to understand the genetic and molecular organisation
M N, Choudhury, A, Uddin, S, Chakraborty
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Codon usage bias in metagenomes
2009Codon usage (CU) bias is an effect predominant in prokaryotes whereby synonymous codons are used with different frequencies between different species and even between genes within a single genome. This effect is related to tRNA abundance and can be used to predict expressivity of proteins by comparing their CU with that of a reference set of ...
Lucić, Vedran +3 more
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Reduced Selection for Codon Usage Bias in Drosophila miranda
Journal of Molecular Evolution, 2007Biased codon usage in many species results from a balance among mutation, weak selection, and genetic drift. Here I show that selection to maintain biased codon usage is reduced in Drosophila miranda relative to its ancestor. Analyses of mutation patterns in noncoding DNA suggest that the extent of this reduction cannot be explained by changes in ...
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The expanding world of tRNA modifications and their disease relevance
Nature Reviews Molecular Cell Biology, 2021Tsutomu Suzuki
exaly