Results 161 to 170 of about 18,552 (255)

Genome‐Wide Association Study Elucidates the Genetic Architecture of Manganese Tolerance in Brassica napus

Plant, Cell &Environment, EarlyView.
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman, Zetao Bai, Brett McVittie, Sourav Mukherjee, Hugh D. Goold, Yuanyuan Zhang, Nay Chi Khin, Yu Qiu, Nawar Shamaya, Shengyi Liu, Regine Delourme, Barry J. Pogson, Sureshkumar Balasubramanian, Rosy Raman   +13 more
wiley   +1 more source

Unconventional codon usage bias mediates mRNA translational dynamics in macrophages. [PDF]

PLoS Biol
Luo S, Wang Q, Chen A, Huang L, Liu Y, Zong X, Mao Y.   +6 more
europepmc   +1 more source

UV signature mutation hyperhotspots as genomic dosimeters

Photochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon, Alejandro García‐Ruiz, Susan Neveu, Brenda Cartmel, Leah M. Ferrucci, Meg Palmatier, Christine Ko, Kenneth Y. Tsai, Mio Nakamura, Sa Rang Kim, Michael Girardi, Karl Kornacker, Douglas E. Brash   +12 more
wiley   +1 more source

Natural Selection Drives Codon Usage Bias in the Mitochondrial Genome of <i>Ligula intestinalis</i> (Linnaeus, 1758) Gmelin, 1790 (Cestoda: Diphyllobothriidea): Insights from Comparative Genomics and Optimal Codon Identification. [PDF]

Animals (Basel)
Wang SJ, Zeng SM, Liu FC, Hu JN, Wang SH, Zhang L, Yue C, Hao CL.   +7 more
europepmc   +1 more source

Letermovir in Refractory and Resistant CMV After Lung Transplantation: Therapeutic Potential and Emergence of Resistance

Transplant Infectious Disease, EarlyView.
Letermovir use for active R/R CMV infection was associated with treatment‐emergent resistance in approximately one‐third of patients, particularly in those with high baseline viral loads and delayed virological response. These findings support careful patient selection, close virological monitoring, and early resistance testing.
Tobias Veit, Stefan Trost, Teresa Kauke, Nina Engels, Gabriela Leuschner, Michael Gerckens, Carlo Mümmler, Sebastian Michel, Michael Zoller, Valeria Hackemann, Jürgen Behr, Nikolaus Kneidinger   +11 more
wiley   +1 more source

Codon Usage Bias Analysis in the Chloroplast Genome of <i>Actinostemma tenerum</i> (Cucurbitaceae). [PDF]

Curr Issues Mol Biol
Mu JJ, Zhang JS.
europepmc   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Codon Usage Bias of the Polyphenol Oxidase Genes in <i>Camellia sinensis</i>: A Comprehensive Analysis. [PDF]

Plants (Basel)
Aktürk Dizman Y.
europepmc   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2719-2737, December 2026.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Comprehensive analysis of 73 Aconitum chloroplast genomes reveals their structure, codon usage bias, and phylogenetic relationships within family Ranunculaceae. [PDF]

Sci Rep
Kakkar RA, Sharma G.
europepmc   +1 more source