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Enzymatic activity of albumin shown by coelenterazine chemiluminescence
Luminescence, 2012ABSTRACTBioluminescence, the emission of light from live organisms, occurs in 18 phyla and is the major communication system in the deep sea. It has appeared independently many times during evolution but its origins remain unknown. Coelenterazine bioluminescence discovered in luminous jellyfish is the most common chemistry causing bioluminescence in ...
Anthony Campbell +2 more
exaly +3 more sources
Oxygen Activation of Apo‐obelin–Coelenterazine Complex
ChemBioChem, 2013AbstractCa2+‐regulated photoproteins use a noncovalently bound 2‐hydroperoxycoelenterazine ligand to emit light in response to Ca2+ binding. To better understand the mechanism of formation of active photoprotein from apoprotein, coelenterazine and molecular oxygen, we investigated the spectral properties of the anaerobic apo‐obelin–coelenterazine ...
Zhi-Jie Liu +2 more
exaly +4 more sources
Coelenterazine: a two-stage antioxidant in lipid micelles
Free Radical Biology and Medicine, 2004Coelenterazine is a luciferin found in many marine bioluminescent organisms. This luciferin also possesses high antioxidant properties and an exceptional ability to protect cells exposed to oxidative stress. It has been suggested that coelenterazine's antioxidative mechanisms include the formation of an oxidation product, coelenteramine, also endowed ...
Jacqueline Marchand-Brynaert +1 more
exaly +3 more sources
Three Efficient Methods for Preparation of Coelenterazine Analogues
Chemistry - A European Journal, 2016AbstractThe growing popularity of bioluminescent assays has highlighted the need for coelenterazine analogues possessing properties tuned for specific applications. However, the structural diversity of known coelenterazine analogues has been limited by current syntheses. Known routes for the preparation of coelenterazine analogues employ harsh reaction
Thomas Kirkland, Thomas Machleidt
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Coelenterazine-dependent luciferases
Biochemistry (Moscow), 2015Bioluminescence is a widespread natural phenomenon. Luminous organisms are found among bacteria, fungi, protozoa, coelenterates, worms, molluscs, insects, and fish. Studies on bioluminescent systems of various organisms have revealed an interesting feature - the mechanisms underlying visible light emission are considerably different in representatives ...
S V, Markova, E S, Vysotski
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Organic Preparations and Procedures International, 2001
(2001). SYNTHESIS OF COELENTERAZINE. Organic Preparations and Procedures International: Vol. 33, No. 5, pp. 477-485.
Maciej Adamczyk +4 more
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(2001). SYNTHESIS OF COELENTERAZINE. Organic Preparations and Procedures International: Vol. 33, No. 5, pp. 477-485.
Maciej Adamczyk +4 more
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Light-emitters involved in the luminescence of coelenterazine
Luminescence, 2000Coelenterazine emits light by chemi-and bioluminescence reactions, decomposing into coelenteramide and CO(2). To ascertain the light emitters involved, the fluorescence of coelenteramide and five analogues were studies in four kinds of solvent. The results showed that coelenteramides can form five kinds of light emitters, ie unionized (lambda(max) 386 ...
O, Shimomura, K, Teranishi
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ChemInform Abstract: Synthesis of Coelenterazine.
ChemInform, 2002AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Maciej Adamczyk +4 more
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Synthetic Bioluminescent Coelenterazine Derivatives
2016The development of coelenterazine (CTZ) derivatives resulting in superior optical characteristics is an efficient method to extend the range of its possible applications. Here, we describe the synthesis of three C-6 substituted CTZ derivatives retaining the recognition by Renilla luciferase (RLuc) and its derivatives.
Ryo, Nishihara +2 more
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Concise Synthesis ofv-Coelenterazines
Organic Letters, 2015A novel synthetic method for v-coelenterazine (v-CTZ), which is a vinylene-bridged analog of native CTZ with a large red-shifted luminescence property, is described. The synthesis was achieved in a concise way through the use of three sequential cross-coupling reactions and ring-closing metathesis (RCM).
Takamitsu, Hosoya +6 more
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