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Autoimmune Diseases, 2014 Coeliac disease is an autoimmune enteropathy triggered by the ingestion of gluten-containing cereals, such as wheat, rye and barley. It is estimated to occur in one per cent of people of European ancestry, and in 0.3% of black Africans. Coeliac disease has a strong genetic component as nearly all patients with the disease share the same genetic ...
NENNA, RAFFAELLA +3 more
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Nature Reviews Disease Primers, 2019 Coeliac disease is an immune-mediated enteropathy against dietary gluten present in wheat, rye and barley and is one of the most common lifelong food-related disorders worldwide. Coeliac disease is also considered to be a systemic disorder characterized by a variable combination of gluten-related signs and symptoms and disease-specific antibodies in ...
Lindfors K. +8 more
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British Medical Bulletin, 2008 Coeliac disease is a common but often under diagnosed condition with important complications. It is due to immune-mediated gluten intolerance and may present in a number of ways. It has become more frequently diagnosed due to the recognition of the atypical presentations.
John S, Leeds +2 more
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Best Practice & Research Clinical Gastroenterology, 2002 Increased awareness of non-classical presentations and more reliable screening tests have led to higher detection rates for coeliac disease in elderly adults. Clinical presentations are influenced largely by the long-standing course of the subclinical disease before diagnosis.
Hugh, Freeman +2 more
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Annals of Nutrition and Metabolism, 1977 In coeliac disease there is an abnormality of the intestinal mucosa which is caused by ingesting gluten. The intestinal lesion affects predominantly the proximal small intestine and the ileum is either normal or less severely involved than the jejunum. In some cases adaptive changes occur in the ileum, producing enhanced absorption in that region when ...
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The Lancet, 1997 Coeliac disease, or gluten sensitive enteropathy is a common disorder and results from exposure to gluten in the diet of genetically susceptible individuals. Environmental factors may influence both the age of presentation and the severity of symptoms.
M, Mäki, P, Collin
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Giardiasis and coeliac disease [PDF]
Archives of Disease in Childhood, 1973 The incidence of Giardia lamblia infestation, as shown by examination of the stools, is the same in normal and coeliac children. 93 patients who were suspected of having coeliac disease had upper intestinal biopsies examined for giardia infestation. These patients usually had at least one stool and/or duodenal juice sample examined for G. lamblia.
T. A. McAllister +2 more
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Epilepsy and coeliac disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1982 A number of neurological disorders have been described in association with coeliac disease, including epilepsy. A review of 177 patients with coeliac disease failed to show an increased prevalence of epilepsy. This is contrary to the findings of other workers, and requires further investigation.
JG Hanly +3 more
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Lymphadenopathy in coeliac disease [PDF]
Gut, 1981 We present two cases of adult coeliac disease whose major clinical feature was marked lymphadenopathy. One patient also displayed a peripheral lymphocytosis which varied with treatment of the underlying disease.
F D Rosenthal, J P Simmonds
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Genetics of coeliac disease [PDF]
QJM, 1996 Coeliac disease is one of the most common gastrointestinal disorders. The clinical features of the disease are protean, possibly due to heterogeneity. A familial basis for coeliac disease is well recognized, and although a strong HLA association is seen, this cannot entirely account for the increased risk seen in relatives of affected cases. A gene (or
D. Ford, Richard S. Houlston
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