Results 11 to 20 of about 24,711 (245)

Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study [PDF]

open access: goldBMJ Open, 2020
Objective Severity of coeliac disease depends in part on the extent of small intestinal mucosa injury. Patients with the most abnormal pathology have loss of duodenal villi CYP3A4, a drug-metabolising enzyme that inactivates many drugs.
Marc L Chretien   +6 more
doaj   +2 more sources

Is mass screening for coeliac disease a wise use of resources? A health economic evaluation

open access: yesBMC Gastroenterology, 2021
Background Living with undiagnosed symptomatic coeliac disease is connected with deteriorated health, and persons with coeliac disease often wait a long time for their diagnosis. A mass screening would lower the delay, but its cost-effectiveness is still
Fredrik Norström   +8 more
doaj   +1 more source

Coeliac disease: no difference in milk and dairy products consumption in comparison with controls

open access: yesBMJ Nutrition, Prevention & Health, 2020
Background Nutritional deficiencies are common in patients with coeliac disease and they can cause osteopenia among other associated diseases. Reduced consumption of milk and dairy products may play a major role in determining low bone mass in patients ...
Carolina Ciacci   +3 more
doaj   +1 more source

Jejunojejunal Intussusception as Initial Presentation of Coeliac Disease: A Case Report and Review of Literature

open access: yesEuropean Medical Journal Gastroenterology, 2021
Intussusception as the initial presentation of coeliac disease has been rarely reported, with an incidence of 1% in all coeliac disease presentations.
Melissa Kyriakos Saad   +5 more
doaj   +1 more source

The global burden of childhood coeliac disease: a neglected component of diarrhoeal mortality? [PDF]

open access: yesPLoS ONE, 2011
OBJECTIVES: Coeliac disease has emerged as an increasingly recognised public health problem over the last half-century, and is now coming to be seen as a global phenomenon, despite a profound lack of globally representative epidemiological data.
Peter Byass   +2 more
doaj   +1 more source

Population-Based Screening for Coeliac Disease in Lithuanian Children from 2009 to 2014

open access: yesMedicina, 2023
Background and Objectives. Coeliac disease is an autoimmune disorder provoked by a dietary group of proteins called gluten in genetically predisposed individuals.
Vaidotas Urbonas   +2 more
doaj   +1 more source

Diagnostic Delay in Coeliac Disease: A Survey among Danish Patients

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2022
Background. Coeliac disease affects around 1% of the population, although many cases remain undiagnosed. Underdiagnosis and diagnostic delay in coeliac disease may cause health complications and be a burden for both the patient and society.
Line Lund Kårhus   +3 more
doaj   +1 more source

Celiac disease in the COVID-19 pandemic

open access: yesJournal of Translational Autoimmunity, 2021
Background: The COVID-19 pandemic has had an impact on global health. Design: The impact of the COVID-19 pandemic on patients with coeliac disease was assessed in the present review.
Gabriel Samasca, Aaron Lerner
doaj   +1 more source

Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping

open access: yesNature Communications, 2019
High-throughput sequencing and analyzes of antibody repertoire provide important information on immune responses, but current methodologies are limited in sequence assembly precision and haplotype inference validity.
Moriah Gidoni   +12 more
doaj   +1 more source

Severity of coeliac disease and clinical management study when using a non-metabolised medication: a phase I pharmacokinetic study

open access: yesBMJ Open, 2023
Objective The non-metabolised antihistamine fexofenadine has oral absorption resulting from transporter activity. Uptake by enterocyte organic anion transporting polypeptides and efflux by an ATP-binding cassette transporter (P-glycoprotein) are primary ...
Marc L Chretien   +6 more
doaj   +1 more source

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