The Omnicausal Model Reveals the Highly Polyfactorial Nature of Complex Diseases
ABSTRACT Mendelian randomization (MR) is a human genetics method for inferring causal relationships between risk factors and diseases. A common focus of MR studies has been on the causal inference of a single risk factor on a single disease. This has led to the successful discovery of numerous causal risk factors for disease.
Carla Márquez‐Luna +4 more
wiley +1 more source
Feasibility and performance of minimal-volume capillary blood screening for type 1 diabetes and coeliac disease autoantibodies across all age groups: the UNISCREEN population study. [PDF]
Marzinotto I +16 more
europepmc +1 more source
Association of Childhood Acute Leukemia With Autoimmune Diseases
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka +4 more
wiley +1 more source
Machine Learning Achieves Pathologist-Level Coeliac Disease Diagnosis. [PDF]
Jaeckle F +9 more
europepmc +1 more source
ABSTRACT Background Data on the global prevalence of alarm features in the general population and among individuals with disorders of gut–brain interaction (DGBI) are limited. Methods We analysed data from the Rome Foundation Global Epidemiology Study to estimate the prevalence of fourteen self‐reported alarm features in the global population and among
Jessica Sjölund +7 more
wiley +1 more source
Faecal biomarkers in children with coeliac disease: A way forward? [PDF]
Kivelä L +4 more
europepmc +1 more source
The oscillatory response of the electroretinogram and neuronal adaptation
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley +1 more source
<i>BTN2A1</i> and <i>BTN3A1</i> as Novel Coeliac Disease Risk Loci: An In Silico Analysis. [PDF]
Luu Hoang KN +8 more
europepmc +1 more source
ABSTRACT Aim To assess the proportion of children with Down syndrome (DS) with creatinine levels above standard paediatric reference ranges in a single‐centre Irish outpatient cohort. Methods We performed a retrospective cross‐sectional study of children aged 0–16 years attending the DS Clinic at Children's Health Ireland, Tallaght, between June 2022 ...
C. Broderick Farrell +6 more
wiley +1 more source
Research Communication: Prevalence of Acute Reactions After Gluten Ingestion in Patients With Coeliac Disease-A Retrospective Study. [PDF]
Avino G +6 more
europepmc +1 more source

