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Coeliac disease in childhood

BMJ, 2009
An 11 year old boy explains how coeliac disease affects him, and his parents tell of the obstacles to the ...
Henry W M, Willis   +4 more
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Coeliac disease and malignancies

Acta Paediatrica, 1996
When compared with the general population, patients with coeliac disease (CD) have an increased risk of developing enteropathy‐associated T‐cell lymphoma (EATCL), esophageal and pharyngeal squamous carcinomas and small intestinal adenocarcinomas. The prevalence of histologically confirmed CD in Edinburgh and the Lothians in 1979 was 61 per 100000.
A, Ferguson, K, Kingstone
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Diagnosis of coeliac disease

Best Practice & Research Clinical Gastroenterology, 2005
The diagnosis of coeliac disease depends on the finding of characteristic, though not specific changes, of intraepithelial lymphocytosis, crypt hyperplasia and various degrees of villous height reduction identified in duodenal biopsies of individuals ingesting a gluten containing diet, together with symptomatic and histologic improvement on gluten ...
Peter H R, Green   +2 more
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Coeliac disease in children

BMJ, 2018
### What you need to know A 3 year old boy is brought to his general practitioner by his mother. She is worried he is waking at night complaining of abdominal pain. He has smelly stools that float in the toilet, and has a cousin with coeliac disease. His growth has fallen from the 25th to the second centile for height and weight. On examination he has
Philippa C, Thomas   +2 more
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Hypoalbuminaemia and coeliac disease

Gut, 2008
A 23-year-old woman was diagnosed with coeliac disease with positive serology and typical duodenal histology. A gluten-free diet was instituted. About 9 months later, she presented with bipedal oedema that developed overnight, associated with a fall in …
Gibson, PR   +5 more
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Coeliac disease in children

Best Practice & Research Clinical Gastroenterology, 2005
Although coeliac disease (CD) can present at any age, including the elderly, typical cases often manifest in early childhood. The clinical spectrum in children is wide and includes: (1) typical cases presenting early in life with signs of intestinal malabsorption (chronic diarrhea, weight loss, abdominal distention, etc); (2) atypical cases showing ...
Alessio, Fasano, Carlo, Catassi
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Advances in coeliac disease

Current Opinion in Gastroenterology, 2014
To summarize the recent advances in coeliac disease.Details of the polygenic nature of coeliac disease with the human leukocyte antigen (HLA) locus as the dominating genetic element have been uncovered. The existence of a large number of non-HLA coeliac disease genes, only partly shared by each individual patient, suggests the genetic heterogeneity of ...
Lundin KEA, Sollid LM
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The prevention of coeliac disease

Best Practice & Research Clinical Gastroenterology, 2015
Primary prevention of coeliac disease is currently not possible. Previously, a 'window of opportunity' was suggested for primary prevention, by introducing gluten between four and six months of age. However, results from recent prospective studies establish that the timing of gluten introduction and the duration or maintenance of breastfeeding do not ...
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A History of Coeliac Disease

Digestive Diseases, 2008
Coeliac disease may have an ancient history dating back to the 1st and 2nd centuries AD. The first clear description was given by Samuel Gee in 1888. He suggested that dietary treatment might be of benefit. In the early 20th century various diets were tried, with some success, but without clear recognition of the toxic components.
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Coeliac Disease

Scottish Medical Journal, 1970
A, Ferguson, A S, McNeish
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