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Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source
Gastrointestinal microbiome and gluten in celiac disease
Coeliac disease (CD), also known as gluten sensitive enteropathy, is an autoimmune intestinal disease induced by gluten in genetically susceptible individuals.
Xingxing Wu+4 more
doaj +1 more source
Epilepsy and coeliac disease [PDF]
A number of neurological disorders have been described in association with coeliac disease, including epilepsy. A review of 177 patients with coeliac disease failed to show an increased prevalence of epilepsy. This is contrary to the findings of other workers, and requires further investigation.
JG Hanly+3 more
openaire +3 more sources
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song+16 more
wiley +1 more source
This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in 69 patients who underwent R0 salvage surgery for esophageal squamous cell carcinoma. Of note, abdominal LN metastases had a negative impact on survival in our series.
Kotaro Sugawara+9 more
wiley +1 more source
Genetics of coeliac disease [PDF]
Coeliac disease is one of the most common gastrointestinal disorders. The clinical features of the disease are protean, possibly due to heterogeneity. A familial basis for coeliac disease is well recognized, and although a strong HLA association is seen, this cannot entirely account for the increased risk seen in relatives of affected cases. A gene (or
D. Ford, Richard S. Houlston
openaire +3 more sources
This multi‐institutional, randomized, phase II trial aimed to investigate the long‐term survival outcomes of two versus three courses of DCF for locally advanced esophageal squamous cell carcinoma (ESCC). The 5‐year overall survival and progression‐free survival rates for the three and two course groups were 70.7% vs. 63.8% (hazard ratio (HR) = 0.91, p
Takahito Sugase+19 more
wiley +1 more source
Objective The environmental trigger behind the increasing prevalence of coeliac disease is not known. One suggested cause is iron deficiency, which is common in coeliac disease. We aimed to evaluate this possible association with Mendelian randomisation (
Isabel A Hujoel+1 more
doaj +1 more source
The Russian consensus on diagnosis and treatment of coeliac disease in children and adults
Accepted at 42nd Scientific Session of the Central Research Institute of Gastroenterology, Moscow, March 2-3, 2016.The consensus has been developed by the leading experts in gastroenterology and pediatrics of Russia. It is based on the guidelines "Gluten
Editorial article
doaj +1 more source
Our present study reveals that surgical step recognition performs moderately well when trained on video data from a single institution and applied to an external institution's data. Nevertheless, our model substantially improves its prediction capabilities when trained on the same amount of data from multiple institutions.
James S. Strong+8 more
wiley +1 more source