Patterns of clinical presentation of adult coeliac disease in a rural setting
Nutrition Journal, 2006 Background In recent years there has been increasing recognition that the pattern of presentation of coeliac disease may be changing. The classic sprue syndrome with diarrhoea and weight loss may be less common than the more subtle presentations of ...
D'Souza Charles +2 more
doaj +1 more source
Multiple-instance-learning-based detection of coeliac disease in histological whole-slide images
Journal of Pathology Informatics, 2022 We present a multiple-instance-learning-based scheme for detecting coeliac disease, an autoimmune disorder affecting the intestine, in histological whole-slide images (WSIs) of duodenal biopsies.
J. Denholm +11 more
doaj +1 more source
Random duodenal biopsy to exclude coeliac disease as a cause of anaemia is not cost‑efective and should be replaced with universally performed pre‑endoscopy serology in patients on a suspected cancer pathway [PDF]
, 2018 Background: Random duodenal biopsy to exclude coeliac disease during upper gastrointestinal endoscopy for the investigation of iron defciency anaemia remains a common procedure, but is expensive and time-consuming.
Herrod, Philip, Lund, Jonathan N.
core +2 more sources
GastroenterologyBACKGROUND & AIMS Current international guidelines recommend duodenal biopsies to confirm the diagnosis of coeliac disease in adult patients. However, growing evidence suggests that IgA anti-tissue transglutaminase (tTg) antibody levels ≥10 times the ...
Mohamed G. Shiha +9 more
semanticscholar +1 more source
Persistent changes in circulating and intestinal γδ T cell subsets, invariant natural killer T cells and mucosal-associated invariant T cells in children and adults with coeliac disease. [PDF]
PLoS ONE, 2013 Coeliac disease is a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals. The only current therapy is a lifelong gluten free diet.
Margaret R Dunne +6 more
doaj +1 more source
Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo [PDF]
, 2019 Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from Rothia mucilaginosa, a natural ...
Darwish, Ghassan +4 more
core +1 more source
Diagnostic Utility of Coeliac Disease: A Descriptive Study in a Tertiary Care Hospital, Oman
Oman Medical Journal, 2013 Objectives: The prevalence of coeliac disease in Oman is unknown. We aim to estimate the prevalence of coeliac disease in at-risk subjects, describe the clinical characteristics and laboratory findings associated with coeliac disease and the validity of ...
Safana Salim Al Saidi +2 more
doaj +1 more source
Serum Citrulline and Ornithine: Potential Markers of Coeliac Disease Activity
Acta Medica, 2023 Introduction: To date, there is not generally accepted and universal indicator of activity, and functional integrity of the small intestine in patients with coeliac disease.
Ladislav Douda +15 more
doaj +1 more source
The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile [PDF]
, 2018 The study evaluated the symptoms, acceptance, and digestibility of bread made from transgenic low-gliadin wheat, in comparison with gluten free bread, in Non-coeliac gluten sensitivity (NCGS) patients, considering clinical/sensory parameters and gut ...
Comino Montilla, Isabel María +10 more
core +1 more source
Gut, 2019 Objective Higher gluten intake, frequent gastrointestinal infections and adenovirus, enterovirus, rotavirus and reovirus have been proposed as environmental triggers for coeliac disease.
K. Lindfors +16 more
semanticscholar +1 more source