Results 71 to 80 of about 5,784 (241)
ABSTRACT Auto‐inflammatory diseases can exhibit a wide variety of clinical symptoms, which often result in delays in diagnosis and treatment for patients. Intestinal inflammation is a clinical symptom frequently observed in auto‐inflammatory syndromes.
Maryam Khalesi +5 more
wiley +1 more source
The sea urchin, Strongylocentrotus purpuratus has seven described populations of distinct coelomocytes in the coelomic fluid that are defined by morphology, size, and for some types, by known functions. Of these subtypes, the large phagocytes are thought
Megan A. Barela Hudgell +2 more
doaj +1 more source
Echinoderm Immunology: Bacterial clearance by the sea urchin, Strongylocentrotus purpuratus [PDF]
Characteristics of bacterial clearance were investigated in the purple sea urchin, Strongylocentrotus purpuratus (Echinodermata: Echinoidea). Primary clearance kinetics were determined for three bacteria, a marine Gram negative motile rod, a marine Gram ...
Bayne, Christopher J., Yui, Mary A.
core +1 more source
Sea stars have remarkable regenerative capabilities. A peptide, KASH2, identified in the biofluid of the common sea star Asterias rubens appears to be involved with the wound‐healing response in the organism. Here, we show the 3D structure of KASH2 adopts a disulfide‐directed β‐hairpin fold, a fold only previously found in arachnids, and does not show ...
Rozita Takjoo +10 more
wiley +1 more source
Comparative DNA damage and repair in echinoderm coelomocytes exposed to genotoxicants. [PDF]
The capacity to withstand and repair DNA damage differs among species and plays a role in determining an organism's resistance to genotoxicity, life history, and susceptibility to disease.
Ameena H El-Bibany +2 more
doaj +1 more source
Detection of vitellogenin in a subpopulation of sea urchin coelomocytes [PDF]
Sea urchin vitellogenin is a high molecular weight glycoprotein, which is the precursor of the major yolk protein present in the unfertilized egg. Vitellogenin processing into the major yolk protein and its further enzymatic cleavage during sea urchin ...
ARIZZA, Vincenzo +4 more
core
Selection Over Small and Large Spatial Scales in the Face of High Gene Flow
ABSTRACT Local adaptation represents the balance of selection and gene flow. Increasingly, studies find that adaptation can occur on spatial scales much smaller than the scale of dispersal, resulting in balanced polymorphisms within populations.
Camille Rumberger +7 more
wiley +1 more source
The first determination of presence and biodistribution of PFOA in ninety specimens of sea urchin Paracentrotus lividus from two differently contaminated sites along Palermo’s coastline (Sicily) is reported.
Dario Savoca +7 more
doaj +1 more source
Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process [PDF]
© The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology of the Cell 26 (2015): 887-900, doi:10.1091/mbc.E14-07-1244.Recent studies have ...
Brown, Briana L. +8 more
core +1 more source
HSP110 is a modulator of amyloid beta (Aβ) aggregation and proteotoxicity
To prevent proteotoxicity, the cell has evolved a proteostasis network comprised of molecular chaperones and proteolytic pathways. HSP110 is a poorly characterized chaperone that has recently been implicated in Alzheimer's disease. In vitro studies have shown that human HSP110 can inhibit Aβ1‐42 fibril formation either alone or with other chaperones ...
Sabrina Montresor +13 more
wiley +1 more source

