Results 91 to 100 of about 133,360 (260)

Nitrogen and carbon flows in a microbial mat involving anaerobic oxidation of methane in northwestern Black Sea: perspectives from nitrogen and carbon isotopic composition of coenzyme F430 and its biosynthetic pathway

Progress in Earth and Planetary Science
Coenzyme F430, a nickel-containing tetrapyrrole, serves as a cofactor for methyl-coenzyme M reductase (MCR), which catalyzes both the final step of methanogenesis and the initial step of anaerobic oxidation of methane (AOM).
Masanori Kaneko, Yoshinori Takano, Yuta Isaji, Nanako O. Ogawa, Yoshito Chikaraishi, Naoto F. Ishikawa, Hiroyuki Imachi, Yoshihiro Takaki, Miyuki Ogawara, Fumie Kabashima, Martin Krüger, Naohiko Ohkouchi   +11 more
doaj   +1 more source

“Coenzyme Q10” (Coenzym Q10) [PDF]

IIC - International Review of Intellectual Property and Competition Law, 2016
openaire   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

CoQ10 mitigates BPA-induced cardiotoxicity by maintaining cellular antioxidant levels and Na+/K+-ATPase and Ca2+-ATPase activities

Scientific African
Background: Bisphenol A is an endocrine disruptor widely used by humans, and has diverse toxic effects, such as cardiotoxicity. The cardiotoxic effect of Bisphenol A is multifaceted and includes the depletion of cellular antioxidants and impairment of Na+
W.A. Saka, A.A. Oladipo, C.A. Adegbola, O.E. Adelowo, P.A. Oyedokun, O.R. Kolawole, M.T. Owoeye, T.M. Akhigbe, A.Y. Onaolapo, R.E. Akhigbe   +9 more
doaj   +1 more source

An all‐in‐one fucosylated gold nanocluster probe enables NIR‐II imaging and multi‐mechanistic therapy of acute kidney injury

BMEMat, EarlyView.
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang, Boning Tan, Suqing Feng, Beibei Gu, Ting Feng, Haiguang Zhu, Jianping Xie, Xun Yuan   +7 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Rationales for the Choice of Metals for Super‐Reduced Biological Metal Centers: Cobalt in Cobalamin Versus Nickel in F430

Chemistry – A European Journal, EarlyView.
DFT calculations on porphyrin, corrin, and corphin complexes of cobalt, rhodium, iron, manganese, or nickel, and QM/MM calculations on enzyme models, explore the factors controlling the availably of super‐reduced metal(I) states. True metal(I) states are seen in corrin only for cobalt, in corphin only for nickel, and not at all in porphyrin.
Radu‐Ioan Onija, Sergiu‐Raul Cosma, Adrian M. V. Brânzanic, Radu Silaghi‐Dumitrescu   +3 more
wiley   +1 more source

Examining Effects of Metformin and Coenzyme Q10 on Doxorubicin-Induced Oxidative Hepatotoxicity in Rats [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Cancer is considered one of the most common causes of mortality, in today’s world. A growing body of evidence has demonstrated that the global cancer burden is expected to rise significantly in the years to come.
Mohammad Bahrami, Pouria Sobhi, Faraz Mahdizadeh, Shiva Rahimi, Lida Khodaei, Masoud Ojarudi, Aliakbar Fazaeli, Ramin Salimnejad, Lotfollah Rezagholizadeh   +8 more
doaj  

ISOLATION OF COENZYME A

Journal of Biological Chemistry, 1950
F, LIPMANN, N O, KAPLAN, G D, NOVELLI, L C, TUTTLE, B M, GUIRARD   +4 more
openaire   +2 more sources

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

Chemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić, Roy Steneker, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov   +4 more
wiley   +1 more source