Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors.
V. I. Zozina +3 more
doaj
Acyl-Coenzyme A:Cholesterol Acyltransferase Inhibition Ameliorates Proteinuria, Hyperlipidemia, Lecithin-Cholesterol Acyltransferase, SRB-1, and Low-Denisty Lipoprotein Receptor Deficiencies in Nephrotic Syndrome [PDF]
Nosratola D. Vaziri, Kuo-huan Liang
openalex +1 more source
Anticoagulation Overdose When Receiving Vitamin K Antagonists Combined with Coenzyme Q10: Review of the World's Medicine [PDF]
Si Dung Chu, Minh Thi Tran
openalex +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source

